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16961
Global transcriptional modulation and nutritional status of soybean plants following foliar application of zinc borate as a suspension concentrate fertilizer
Published 2025-01-01“…Furthermore, a gene lacking functional annotation (Glyma.03G180300) emerged as a novel potential marker of B status. Two genes (Glyma.16G118000, Glyma.16G199000) were consistently induced by Zn availability, highlighting their potential as biomarkers for assessing its status in soybean plants. …”
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16962
Natural products targeting RAS by multiple mechanisms and its therapeutic potential in cancer: An update since 2020
Published 2025-02-01“…Natural products, endowed with unique chemical structures and diverse biological activities through long-term natural selection, have emerged as a vital resource for discovering novel RAS-targeted therapeutic drugs. This review focuses on the latest advancements in targeting RAS with natural products and categorizes these natural products based on their mechanisms of action. …”
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16963
RETRACTED ARTICLE: Enhancing MPPT performance for partially shaded photovoltaic arrays through backstepping control with Genetic Algorithm-optimized gains
Published 2024-02-01“…This study introduces a novel approach to enhance the efficiency of photovoltaic systems in Maroua, Cameroon, by tailoring them to the specific solar dynamics of the region. …”
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16964
Antihypertensive effects of whey protein hydrolysate involve reshaping the gut microbiome in spontaneously hypertension rats
Published 2024-07-01“…Novel angiotensin-converting enzyme (ACE) inhibitory peptides were identified from whey protein hydrolysates (WPH) in vitro in our previous study and the antihypertensive abilities of WPH in vivo were further investigated in the current study. …”
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16965
MTIOT: Identifying HPV subtypes from multiple infection data
Published 2025-01-01“…To address these limitations, we introduce MTIOT (Multiple subTypes In One Time), a novel detection method that utilizes machine learning with a new multichannel integration scheme to enhance HPV-DNA analysis. …”
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16966
Rhegmatogenous retinal detachment: current treatment approaches
Published 2020-06-01“…This paper discusses routine and promising surgical techniques for RRD, compare these techniques, and reviews novel technologies and randomized clinical studies that will sign ificantly improve surgical outcomes.…”
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16967
Synthesis of Iron-Modified Biochar Derived from Rice Straw and Its Application to Arsenic Removal
Published 2019-01-01“…A novel iron-modified biochar (FMBC) derived from rice straw was synthesized using FeCl3 modification for efficient As(V) removal from aqueous solution. …”
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16968
Association between D-dimer to lymphocyte ratio and in hospital all-cause mortality in elderly patients with sepsis: a cohort of 1123 patients
Published 2025-01-01“…BackgroundThe D-dimer to lymphocyte ratio (DLR), a novel inflammatory biomarker, had been shown to be related to adverse outcomes in patients with various diseases. …”
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16969
Simulation of Crowd Evacuation in Asymmetrical Exit Layout Based on Improved Dynamic Parameters Model
Published 2025-01-01“…This paper proposes a novel two-dimensional cellular automaton model for multi-exit evacuation, which simplifies evacuee decision-making in an asymmetrical exit layout within dense crowds. …”
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16970
Investigating LiDAR Metrics for Old-Growth Beech- and Spruce-Dominated Forest Identification in Central Europe
Published 2025-01-01“…This study introduces a novel approach for identifying old-growth forests by optimizing a set of selected LiDAR standards and structural metrics. …”
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16971
Simulation study on converter transformer windings stress characteristics under harmonic current and temperature rise effect
Published 2025-04-01“…Finally, the study proposed and validated a novel winding stress calculation model that incorporates the effects of harmonic current and their associated temperature rise. …”
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16972
Anti-Inflammatory and Antinociceptive Activities of Bufalin in Rodents
Published 2014-01-01“…Taken together, bufalin treatment resulted in in vivo anti-inflammatory and analgesic effects, and bufalin may be a novel, potential drug for the treatment of inflammatory diseases.…”
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16973
Dynamics and drivers of the carbonate system: response to terrestrial runoff and upwelling along the Northeastern Colombian Caribbean coast
Published 2025-01-01“…This study provides a novel 6-year time-series dataset for the carbonate system in the Colombian Caribbean, offering a valuable baseline for assessing the impacts of global warming and ocean acidification in the region.…”
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16974
SIX1 aggravates the progression of spinal cord injury in mice by promoting M1 polarization of microglia
Published 2025-01-01“…Overall, the results suggest that SIX1 promotes M1 polarization of microglia following SCI by upregulating the VEGF-C/VEGFR3 axis, whereas the blockade of SIX1 can improve the recovery of locomotor function following SCI, demonstrating a novel strategy for the treatment of SCI.…”
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16975
Stage-specific function of sphingolipid synthases in African trypanosomes
Published 2025-02-01“…This work details the function of each SLS in both bloodstream and insect form parasites. Novel and unexpected sphingolipid dependences are found in each stage. …”
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16976
The association of lipid accumulation product with inflammatory parameters and mortality: evidence from a large population-based study
Published 2025-02-01“…This study aimed to explore the association between a novel marker of lipid accumulation, the abdominal volume index (AVI), inflammatory parameters, and mortality.MethodsThis study enrolled 2,109 older adult senior citizens (aged over 60 years) with hypertension from the National Health and Nutrition Examination Survey. …”
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16977
Genetic insight into dissecting the immunophenotypes and inflammatory profiles in the pathogenesis of Sjogren syndrome
Published 2025-01-01“…Conclusions By providing a novel genetic insight into unveiling the roles of autoimmunity and inflammation in Sjogren syndrome, our findings may potentially lead to identifying new clinical biomarkers for disease monitoring and therapeutic targets that offer more effective alternatives for treating this condition. …”
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16978
Antimicrobial Properties of α-MSH and Related Synthetic Melanocortins
Published 2006-01-01“…Synthetic derivatives, chemically stable and resistant to enzymatic degradation, could form the basis for novel therapies that combine anti-inflammatory and antimicrobial properties.…”
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16979
The association between dolutegravir-based antiretrovirals and high blood pressure among adults with HIV in southern Ethiopia: a cross-sectional study
Published 2024-12-01“…Background: Dolutegravir (DTG), a novel antiretroviral therapy (ART) for HIV, is increasingly adopted across sub-Saharan Africa. …”
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16980
A Simplified Method for Evaluating Chitin-Binding Activity Applied to YKL-40 (HC-gp39, CHI3L1) and Chitotriosidase
Published 2024-12-01“…In this study, we establish a novel chitin-binding affinity evaluation method using a three-step buffer system to assess the binding strength and specificity of chitin-binding proteins and apply it to characterize YKL-40’s binding mechanism. …”
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