20(S)-Ginsenoside Rg3 Protects Kidney from Diabetic Kidney Disease via Renal Inflammation Depression in Diabetic Rats by Tong Zhou, Lin Sun, Shuo Yang, You Lv, Yue Cao, Xiaokun Gang, Guixia Wang

“…The results of the current study suggest that 20(S)-Rg3 could potentially be used as a novel treatment against DKD.…”
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Potential of emodepside for vector-borne disease control by Pattarapon Khemrattrakool, Thitipong Hongsuwong, Theerawit Phanphoowong, Patchara Sriwichai, Kittiyod Poovorawan, Joel Tarning, Kevin C. Kobylinski

“…Emodepside induced mortality in An. dirus does suggest that the SLO-1 channel could be a potential target for novel vector control and may warrant further investigation.…”
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Structural insights on anti-biofilm mechanism of heated slightly acidic electrolyzed water technology against multi-resistant Staphylococcus aureus biofilm on food contact surface by Pianpian Yan, Ramachandran Chelliah, Kyoung Hee Jo, Xiuqin Chen, Akanksha Tyagi, Hyeon Yeong Jo, Fazle Elahi, Nam Chan Woo, Min Seung Wook, Deog Hwan Oh

“…Slightly acidic electrolyzed water (SAEW) has proven to be an efficient and novel sanitizer in food and agriculture field. This study assessed the efficacy of SAEW (30 mg/L) at 40 ℃ on the inactivation of foodborne pathogens and detachment of multi-resistant Staphylococcus aureus (MRSA) biofilm. …”
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Optimization of photocatalytic degradation of Eriochrome Black T from aqueous solution using TiO2-biochar composite by Mohammednur Abdu, Solomon Tibebu, Saeideh Babaee, Abebe Worku, Titus A.M. Msagati, Jemal Fito Nure

“…This study aims to optimize the photocatalytic degradation of Eriochrome Black T dye in aqueous solutions using a novel composite of TiO2 and biochar (BC) as a photocatalyst under UV irradiation. …”
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Carbon finance for forest resilience in California by Micah Elias, Ethan Yackulic, Katharyn Duffy, Katharyn Duffy, Phil Saksa, Daniel L. Sanchez, Nicholas Pevzner, Spencer Plumb, Jillian Dyszynski, Carina Bracer

“…This study shows that carbon revenue from traditional markets or novel carbon contribution programs can help close the funding gap for forest restoration in California while underscoring the need for innovative conservation finance mechanisms to support ecosystem resilience and climate mitigation goals.…”
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Fabrication of hafnium-based nanoparticles and nanostructures using picosecond laser ablation by Abhishek Das, Mangababu Akkanaboina, Jagannath Rathod, R. Sai Prasad Goud, Kanaka Ravi Kumar, Raghu C. Reddy, Ratheesh Ravendran, Katia Vutova, S. V. S. Nageswara Rao, Venugopal Rao Soma

“…Hf ablated in toluene and anisole demonstrated the formation of core–shell NPs of HfC with a graphitic shell. All NPs exhibited novel optical reflectance properties. Reflectance measurements revealed that the fabricated NPs had a very high and broad optical absorption throughout the UV–vis–NIR range. …”
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A multicenter study on TROP2 as a potential targeted therapy for extramammary Paget disease in Japan by Takamichi Ito, Yuka Tanaka, Dai Ogata, Haruto Nishida, Tatsushi Shiomi, Ryo Tanaka, Aya Kawaguchi, Azusa Miyashita, Satoshi Fukushima, Naoko Shojiguchi, Hiroyuki Goto, Yaei Togawa, Takahiro Kiyohara, Yoshinao Oda, Takeshi Nakahara

“…Since efficacy of treatments for metastatic or unresectable EMPD remains poor, development of a novel therapeutic approach is strongly desired. However, the lack of EMPD models has hampered investigation of EMPD. …”
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Co-housing with Tibetan chickens improved the resistance of Arbor Acres chickens to Salmonella enterica serovar Enteritidis infection by altering their gut microbiota composition by Qianyun Zhang, Qidong Zhu, Yunqi Xiao, Qinghua Yu, Shourong Shi

“…This study provides a novel approach for Salmonella control in practical poultry production.…”
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Prospective study of change in liver function and fat in patients with colorectal liver metastases undergoing preoperative chemotherapy: protocol for the CLiFF Study by Katharine Cresswell, Juan W Valle, Michael Braun, Kat L Parmar, Derek O'Reilly, Jo H Naish, Steve R Williams, William K Lloyd, Lee Malcomson, Colin Bamford, Andrew G Renehan

“…Over the past two decades, several tests and derived indices have been developed, which have failed to achieve clinical utility, mainly as they were indirect measurements of liver function. Here, we will use a novel test of liver function (the liver maximum capacity (LiMAx) test), and measure liver fat using MRI.Methods and analysis This prospective study will assess changes in liver function longitudinally, measured by the LiMAx test, and liver fat, measured by advanced MRI using both MR spectroscopy and the modified Dixon method, in up to 35 patients undergoing preoperative chemotherapy for CLM. …”
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A review on techno-economic analysis of lignocellulosic biorefinery producing biofuels and high-value products by Ronak Patel, T.S. Rajaraman, Paresh H. Rana, Nikita J. Ambegaonkar, Sanjay Patel

“…Widespread research in the area has resulted in the development of novel conversion technologies of LCB into useful products. …”
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Poor COVID-19 Preventive Practice among Healthcare Workers in Northwest Ethiopia, 2020 by Belayneh Ayanaw Kassie, Aynishet Adane, Eskeziaw Abebe Kassahun, Amare Simegn Ayele, Aysheshim Kassahun Belew

“…Background. The novel coronavirus disease (COVID-19) pandemic outbreak affects the global social, economic, and political context and becomes a significant threat to healthcare providers who are among the exposed groups to acquire and transmit the disease while caring and treating patients. …”
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A Lightweight Network for Ship Detection in SAR Images Based on Edge Feature Aware and Fusion by Yuming Li, Jin Liu, Xingye Li, Xiliang Zhang, Zhongdai Wu, Bing Han

“…To address these issues, we propose a novel lightweight detection method based on edge feature aware and fusion. …”
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RET Inhibitor SPP86 Triggers Apoptosis and Activates the DNA Damage Response Through the Suppression of Autophagy and the PI3K/AKT Signaling Pathway in Melanoma Cells by Zhang Y, Liu H, Wang K, Zheng J, Luan H, Xin M

“…Yuli Zhang,1,2 Haidong Liu,1 Kun Wang,3 Juan Zheng,4 Hong Luan,1 Ming Xin5 1Department of Dermatology, Liaocheng People’s Hospital, Liaocheng, Shandong, People’s Republic of China; 2Department of Endocrinology, The Second Hospital of Shandong University, Jinan, Shandong, People’s Republic of China; 3Department of Endocrinology and Metabology, Liaocheng People’s Hospital, Liaocheng, Liaocheng, Shandong, People’s Republic of China; 4Joint Laboratory for Translational Medicine Research, Liaocheng People’s Hospital, Liaocheng, Shandong, People’s Republic of China; 5The Key Laboratory of Molecular Pharmacology, Liaocheng People’s Hospital, Liaocheng, Shandong, People’s Republic of ChinaCorrespondence: Ming Xin, The Key Laboratory of Molecular Pharmacology, Liaocheng People’s Hospital, Liaocheng, Shandong, People’s Republic of China, Email xinming137@163.com Hong Luan, Department of Dermatology, Liaocheng People’s Hospital, Liaocheng, Shandong, People’s Republic of China, Email lcsrmyy@126.comBackground: Melanoma is a highly lethal form of skin cancer, and effective treatment remains a significant challenge. SPP86 is a novel potential therapeutic drug. Nonetheless, the specific influence of SPP86 on autophagy, particularly its mechanisms in the context of DNA damage and apoptosis in human melanoma cells, remains inadequately understood. …”
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Pleuroparenchymal Fibroelastosis: A New Entity within the Spectrum of Rare Idiopathic Interstitial Pneumonias by Karina Portillo, Ignasi Guasch, Caroline Becker, Felipe Andreo, Maria Teresa Fernández-Figueras, José Ramirez Ruz, Carlos Martinez-Barenys, Samuel García-Reina, Pedro Lopez de Castro, Irene Sansano, Ana Villar, Juan Ruiz-Manzano

“…That is why better awareness with the clinical and radiologic features can help optimal management by the multidisciplinary team. Novel invasive techniques such as cryobiopsy may become useful tools in these patients as it could spare SLB. …”
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A self-configuration framework for balancing services in the fog of things by Edson Mota, Jurandir Barbosa, Gustavo B. Figueiredo, Maycon Peixoto, Cássio Prazeres

“…Within this context, this paper presents a novel self-organizing environment based on the Fog of Things approach, designed to address these challenges. …”
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Association of Immune Nutrition Indices with the Risk of All-Cause Mortality and Cardiovascular Mortality in Patients with Heart Failure in the NHANES (1999–2018) by Feifei Zhang, Yuetao Xie, Litian Liu, Huiliang Liu, Ohua Feng, Yingxiao Li, Yi Dang

“…Malnutrition is prevalent in patients with HF and disrupts the equilibrium of immune and inflammatory responses, resulting in further deterioration of the HF. Novel indicators emerge as immune nutrition indices, including the prognostic nutritional index (PNI), neutrophil-to-lymphocyte ratio (NLR), Controlling Nutritional Status (CONUT) score, and cholesterol-modified prognostic nutritional index (CPNI). …”
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The XIAP inhibitor AZD5582 improves the treatment effect of microwave ablation on hepatocellular carcinoma by Wenhui Wang, Fuyuan Wu, Zhe Wu, Mengfan Zhang, Qiang Lu

“…However, the residual tumor, resulting from insufficient ablation, led to recurrence and metastasis of liver cancer. Novel combination strategies are urgently needed to enhance efficiency of MWA.MethodsWe detected the expression of XIAP protein after ablation in primary liver cancer patients using immunohistochemistry. …”
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Pioglitazone Attenuates Drug-Eluting Stent-Induced Proinflammatory State in Patients by Blocking Ubiquitination of PPAR by Zhongxia Wang, Tao Zhang, Lizhe Sun, Ruifeng Li, Yuanyuan Wei, Xiaojuan Fan, Zuyi Yuan, Junhui Liu, Tao Chen

“…PIO treatment attenuated DES-induced PPAR loss, NF-κB activation, and proinflammation, indicating that PIO may have a novel direct protective role in modulating proinflammation in DES era.…”
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ReliefF guided variable spiral tuna swarm optimization algorithm with somersault foraging for feature selection by Yu-Cai Wang, Jie-Sheng Wang, Min Zhang, Hao-Ming Song, Jia-Ning Hou, Yu-Liang Qi, Yu-Wei Song

“…Firstly, inspired by the sudden flipping behavior of manta rays when capturing plankton, a novel somersault foraging strategy is introduced to help the TSO algorithm escape from local optima. …”
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Spontaneous tumor regression following COVID-19 vaccination by Hui Dai, Renata Ferrarotto, Myrna Godoy, Diana Bell, Shiaw-Yih Lin, Daniel J McGrail, Luana Guimaraes de Sousa, Kaiyi Li, Mario L Marques-Piubelli, Cipriano Gonzalez, Sammy Ferri-Borgogno, Jared Burks

“…Tumor regression can occur following an intense immune-inflammatory response and novel strategies to treat cancer rely on manipulating the host immune system. …”
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