Potential prebiotic effects of nonabsorptive components of Keemun and Dianhong black tea: an in vitro study by Wenjing Liao, Wenjiao Li, Suyu Liu, Dong Tang, Yunxi Chen, Yijun Wang, Zhongwen Xie, Jinbao Huang

“…In summary, the nonabsorptive components of KBT and DBT could serve as novel prebiotics, the underlying mechanisms of which are quite different from those of FOS.…”
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Immune and Inflammation in Acute Coronary Syndrome: Molecular Mechanisms and Therapeutic Implications by Haiming Wang, Zifan Liu, Junjie Shao, Lejian Lin, Min Jiang, Lin Wang, Xuechun Lu, Haomin Zhang, Yundai Chen, Ran Zhang

“…We also provide a “from bench to bedside” perspective of a novel and promising personalized strategy in RIR intervention and therapeutic approaches for the treatment of ACS.…”
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Teaching undergraduate medical students virtual consultation skills: a mixed-methods interventional before-and-after study by Edie Booth, Kate McFetridge, Evelyn Ferguson, Catherine Paton

“…Objectives To evaluate the impact and transferability of a novel teaching method on virtual communication skills for final year medical students.Design Mixed-methods, interventional before-and-after study.Setting NHS Lanarkshire, Scotland.Participants 21 final year medical students on their obstetrics and gynaecology (O&G) placement from September to December 2020.Interventions A two-part teaching session on virtual communication skills.Main outcome measures Self-reported confidence in conducting consultations preteaching and post-teaching, exposure to virtual consultations, usefulness of teaching and transferability to primary care. …”
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An interactive, online decision aid assessing patient goals and preferences for treatment of aortic stenosis to support physician-led shared decision-making: Early feasibility pilo... by Megan Coylewright, Diana Otero, Brian R Lindman, Melissa M Levack, Aaron Horne, Long H Ngo, Melissa Beaudry, Hannah V Col, Nananda F Col

“…We assessed the feasibility and impact of a novel decision aid for severe aortic stenosis at point-of-care.…”
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Metformin in COVID-19: a magical role beyond the hyperglycemia by Gaurav Kumar Chaubey, Rahul Dilawari, Radheshyam Modanwal, Sharmila Talukdar, Asmita Dhiman, Manoj Raje

“…Researchers confront a worrying situation to rapidly develop effective strategies to combat this novel infection and its long-term aftereffects. To date, there have been myriad reports ranging from the repurposing of the classical antimalarial drug hydroxychloroquine to several other antiviral and anti-bacterial agents like remdesivir, favipiravir, and most recently azithromycin, which has entered clinical use in many countries for combating COVID-19 infections. …”
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Rapid Detection of microRNA-122 in Serum and Finger Blood Using a Lateral Flow Nucleic Acid Biosensor by Min Zhang, Meijing Ma, Jiahui Wang, Yurui Zhou, Xueji Zhang, Guodong Liu

“…In this paper, we present a novel rapid testing method utilizing a lateral flow nucleic acid biosensor (LFNAB) for the sensitive and time-efficient detection of miR-122. …”
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Network Representation Based on the Joint Learning of Three Feature Views by Zhonglin Ye, Haixing Zhao, Ke Zhang, Zhaoyang Wang, Yu Zhu

“…Based on the above two optimization approaches, we propose a novel network representation learning algorithm, Network Representation learning algorithm based on the joint optimization of Three Features (TFNR). …”
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Aberrant DNA Methylation of FTH-1 and SHOX2 Contributes to Lung Cancer Progression by Salar Tahmasbi, Armin Sadeghi, Habib Zarredar, Milad Asadi, Shahryar Hashemzadeh, Venus Zafari, Hamed Sabbagh-Jadid, Mortaza Raeisi

“…Ferritin heavy chain 1 (FTH-1) and SHOX homeobox 2 (SHOX2) DNA methylation were investigated in non-small cell lung cancer (NSCLC) as novel epigenetic biomarkers.Method: In this case-control study, we initially evaluated the diagnostic value of FTH-1 and SHOX2 DNA methylation, and the Cancer Genome Atlas (TCGA) data on the methylation profile of NSCLC was analyzed. …”
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Characterising SRD5A2 Gene Variants in 37 Indonesian Patients with 5-Alpha-Reductase Type 2 Deficiency by Nanis S. Marzuki, Firman P. Idris, Hannie D. Kartapradja, Alida R. Harahap, Jose R. L. Batubara

“…Twelve variants in the SRD5A2 gene were identified, and 6 of which were novel, namely, c.34–38delGinsCCAGC, p.Arg50His, p.Tyr136∗, p.Gly191Arg, p.Phe194Ile, and p.Ile253Val variants. …”
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Modulation of adiposity and adipocyte inflammation by methanol extracts of Alpinia calcarata leaf in high-fat-diet induced-obese mice: Involvement of COX-2 and PPAR-γ by Imtiaz Ahmad, Maruful Hasan, Dipty Rani Bhowmik, Rahima Begum, Sourav Roy, Md Monirul Islam, Md Abdur Rahman Ripon, Mohammad Salim Hossain

“…Taking it all together, it is noteworthy to report this novel function of A. calcarata leaf in reducing adiposity and adipocyte inflammation.…”
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Progress and application of intelligent nanomedicine in urinary system tumors by Yingming Xiao, Lei Zhong, Jinpeng Liu, Li Chen, Yi Wu, Ge Li

“…The conventional therapeutic approaches against urinary tumors are limited by the lack of targeted drug delivery and significant adverse effects, thereby necessitating novel solutions. Intelligent nanomedicine has emerged as a promising therapeutic alternative for cancer in recent years, and uses nanoscale materials to overcome the inherent biological barriers of tumors, and enhance diagnostic and therapeutic accuracy. …”
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Mitigation of PFOA/PFOS toxicity in zebrafish (Danio rerio) by oxidative stress modulation and gut microbial metabolism through the use of aquatic probiotic Lactobacillus rhamnosus by Chun Wang, Guanyi Li, Sibao Chen, Ruixuan Li, Mengyan Wang, Xia Wang, Ning Ding, Yingxue Sun

“…Notably, through the analysis of metabolic pathway differences, it was observed that the PFOA-exposure group exhibited a higher proportion of Rhodococcus in the PWY-7315 pathway, whereas L. rhamnosus mitigated this trend. These novel findings not only elucidate the mechanism by which L. rhamnosus efficiently reduces PFOS and PFOA toxicity in zebrafish but also provide a theoretical basis and practical recommendations for utilizing probiotics in aquaculture.…”
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Oral Fusobacterium nucleatum resists the acidic pH of the stomach due to membrane erucic acid synthesized via enoyl-CoA hydratase-related protein FnFabM by Xiaocong Li, Shipeng Zhang, Huafang Sheng, Yan Zhen, Buling Wu, Zhuang Li, Dingqiang Chen, Hongwei Zhou

“…These results provide novel insights into the mechanisms underlying the oral bacteria survival in acidic environments and their potential to colonize the intestine; thus, shedding light on the oral-gut axis and its implications on human health.…”
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Chimonanthus nitens Oliv. leaves flavonoids alleviate hyperuricemia by regulating uric acid metabolism and intestinal homeostasis in mice by Wenya Meng, Lingli Chen, Kehui Ouyang, Suyun Lin, Yang Zhang, Jing He, Wenjun Wang

“…Overall, our findings revealed a novel function of CLF as a promising therapeutic candidate for the treatment of hyperuricemia.…”
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Mesenchymal Stem Cells for Cartilage Regeneration of TMJ Osteoarthritis by Dixin Cui, Hongyu Li, Xin Xu, Ling Ye, Xuedong Zhou, Liwei Zheng, Yachuan Zhou

“…In this review, we will briefly discuss the pathogenesis of cartilage degeneration in TMJ OA and emphasize the potential sources of MSCs and novel approaches for the cartilage regeneration of TMJ OA, particularly focusing on the MSC-based therapy and tissue engineering.…”
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Vertical Silicon Nanowire Platform for Low Power Electronics and Clean Energy Applications by D.-L. Kwong, X. Li, Y. Sun, G. Ramanathan, Z. X. Chen, S. M. Wong, Y. Li, N. S. Shen, K. Buddharaju, Y. H. Yu, S. J. Lee, N. Singh, G. Q. Lo

“…This paper reviews the progress of the vertical top-down nanowire technology platform developed to explore novel device architectures and integration schemes for green electronics and clean energy applications. …”
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A Trap-Assisted Photomultiplication-Type Organic Photodetector With High Detectivity From Visible to Shortwave Infrared Light by Jingwen Chen, Claire Qing-Ying Huang, Xin Zhang, Sheng Dong, Xiye Yang

“…By easily tunning the donor/acceptor ratio in bulk-heterojunction layer consisting Poly([2,6&#x2019;-4,8-di(5-ethylhexylthienyl)benzo[1,2-b;3,3-b]dithiophene]{3-fluoro-2[(2-ethylhexyl)carbonyl] thieno[3,4-b]thiophenediyl}) (PTB7-Th) and a novel non-fullerene acceptor (NFA) pendant 2,2&#x2019;-(((2,5-bis(2-octyldodecyl)-3,6-dioxo-2,3,5,6-tetrahydropyrrolo [3,4-c]pyrrole-1,4-diyl)bis(thiophene-5,2-diyl))bis(4-oxonaphthalene-3(4H)-yl-1(4H)-ylidene)) dimalononitrile named DPP-QC, the device shows specifically a high external quantum efficiency (EQE) value of 112% and specific detectivity (D*) over <inline-formula> <tex-math notation="LaTeX">$10^{10}$ </tex-math></inline-formula> Jones at 1200 nm at a light intensity of 0.108 mW/cm2. …”
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A Review of Needle Navigation Technologies in Minimally Invasive Cardiovascular Surgeries—Toward a More Effective and Easy-to-Apply Process by Katharina Steeg, Gabriele Anja Krombach, Michael Horst Friebe

“…<b>Conclusions:</b> This review derived the criteria and obstacles an ideal needle navigation system must address before its clinical adoption, along with novel technological approaches that show potential to overcome those challenges. …”
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Molecularly redefining small bowel adenocarcinoma to accelerate precision patient care – protocol of a multicenter observational cohort biomarker study by Rasmus Haunstrup Døssing, Julia Johanna Almer Broman, Colm J. O’Rourke, Elizaveta Mitkina Tabaksblat, Jesper Bøje Andersen, Carsten Palnæs Hansen, Tim Svenstrup Poulsen, Estrid V. S. Høgdall, Jakob Hagen Vasehus Schou, Dan Høgdall

“…Discussion The molecular and clinical characterization of SBA is expected to add novel insights into the heterogeneity of this rare disease. …”
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Advances in Cardiovascular Multimodality Imaging in Patients with Marfan Syndrome by Marco Alfonso Perrone, Sara Moscatelli, Giulia Guglielmi, Francesco Bianco, Deborah Cappelletti, Amedeo Pellizzon, Andrea Baggiano, Enrico Emilio Diviggiano, Maria Ricci, Pier Paolo Bassareo, Akshyaya Pradhan, Giulia Elena Mandoli, Andrea Cimini, Giuseppe Caminiti

“…This review underscores the importance of a comprehensive imaging approach to improve outcomes and guide interventions in MFS patients. It also introduces novel aspects of multimodality approaches, emphasizing their impact on early detection and management of cardiovascular complications in MFS.…”
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