Predicting breast cancer recurrence using deep learning by Deepa Kumari, Mutyala Venkata Sai Subhash Naidu, Subhrakanta Panda, Jabez Christopher

“…This study introduces the BCR-HDL (Breast Cancer Recurrence using Hybrid Deep Learning) framework, a novel approach designed to predict breast cancer recurrence with high accuracy and interpretability. …”
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Unravelling the TCRβ repertoire: a key to unlocking the immunopathogenesis and precision medicine in SLE by Qiao Zhou, Li Zeng, Zhixin Zhang, Jian Liu, Yichen Zhang, Yang An, Lijing Yang, Tianzuo Lan, Pengming He, Xueping Wen, Shaoping Deng

“…The identified hub genes may serve as novel biomarkers for SLE, and the findings contribute to the understanding of the immunopathogenesis of the disease.…”
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Deep Learning Framework for Advanced De-Identification of Protected Health Information by Ahmad Aloqaily, Emad E. Abdallah, Rahaf Al-Zyoud, Esraa Abu Elsoud, Malak Al-Hassan, Alaa E. Abdallah

“…This paper introduces a novel approach, leveraging a Bi-LSTM-CRF model to achieve accurate and reliable PHI de-identification, using the i2b2 dataset sourced from Harvard University. …”
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Single Nucleotide Polymorphisms in PPARD Associated with Systemic Lupus Erythematosus in Chinese Populations by Yuan-yuan Qi, Ya-ling Zhai, Xin-ran Liu, Xiao-xue Zhang, Ya-fei Zhao, Xiang-hui Ning, Zhan-Zheng Zhao

“…In conclusion, our study identified a novel association between PPARD rs4713853 and SLE susceptibility in Chinese populations. …”
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Copper homeostasis and neurodegenerative diseases by Yuanyuan Wang, Daidi Li, Kaifei Xu, Guoqing Wang, Feng Zhang

“…Ultimately, we collate evidence that copper homeostasis may function in the underlying etiology of several neurodegenerative diseases and offer novel insights into the potential prevention and treatment of these diseases based on copper homeostasis.…”
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The mirror preference test: A reverse translational approach to study anomalous subjective experience in rats by Daria Chestnykh, Liubov S. Kalinichenko, Stephan von Hörsten, Johannes Kornhuber, Christian P. Müller

“…We propose that limited visual perception that meets brain monoamine sensitization may trigger visual illusions as part of a psychotic-like state in rats. This novel approach can be utilized to test intervention strategies for psychosis in rats.…”
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Caveolin-1 Knockdown Decreases SMMC7721 Human Hepatocellular Carcinoma Cell Invasiveness by Inhibiting Vascular Endothelial Growth Factor-Induced Angiogenesis by Zhi-Bo Zhang, Zheng Shi, Lan-Fang Yang, Hong-Bin Gao

“…Conclusion. Our results reveal a novel mechanism, whereby caveolin-1 positively regulates human HCC cell invasiveness by coordinating VEGF-induced angiogenesis.…”
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Metabolic reprogramming of naïve regulatory T cells by IL-7 and IL-15 promotes their persistence and performance upon adoptive transfer by Jessica Filoni, Arianna Ferrari, Tatiana Jofra, Anna Rita Putignano, Lorenzo Da Dalt, Susanna Cesarano, Carla Di Dedda, Fabrizia Bonacina, Federica Marchesi, Danilo Norata, Chiara Bonini, Lorenzo Piemonti, Paolo Monti

“…However, the final Treg product has limited survival once infused in patients, potentially affecting therapeutic effectiveness. Here, we tested a novel expansion protocol in which highly purified naïve Tregs were expanded with a combination of IL-7 and IL-15, in the absence of IL-2. …”
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Design and synthesis of antiproliferative 2-oxoindolin-3-ylidenes incorporating urea function with potential VEGFR-2 inhibitory properties by Dalia R. Aboshouk, M. Adel Youssef, Siva S. Panda, Benson M. Kariuki, Mohamed S. Bekheit, Ahmed R. Hamed, Walid Fayad, Ahmed A. F. Soliman, Adel S. Girgis

“…The current study is directed towards synthesis of novel antiproliferative 2-oxoindolin-3-ylidenes incorporating urea function with VEGFR-2 properties. …”
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Multi-Temporal Analysis and Techno-Economic Evaluation of Offshore Wind Energy Integration to the Western Interconnection by Li He, Shahnawaz Siddiqui, Sameer Nekkalapu, Sohom Datta, Travis Douville, Konstantinos Oikonomou, Manisha Maharjan

“…Three generation and transmission scenarios across two future representations of the Western Interconnection (WI) are modeled, and detailed production cost modeling (PCM) and power flow (PF) models of each topology were constructed. A novel multi-terminal high voltage direct current (MTDC) model was developed and utilized, and its performance is compared with conventional high voltage direct current (HVDC) radial topology. …”
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β-Glucan-modified nanoparticles with different particle sizes exhibit different lymphatic targeting efficiencies and adjuvant effects by Wen Guo, Xinyue Zhang, Long Wan, Zhiqi Wang, Meiqi Han, Ziwei Yan, Jia Li, Ruizhu Deng, Shenglong Li, Yuling Mao, Siling Wang

“…The results also indicate that β-glucan-modified MSN, with a particle size of ∼100 nm, has a great potential as a vaccine delivery vehicle and immune adjuvant and offers a novel approach for the delivery of multiple therapeutic agents that target other lymph-mediated diseases.…”
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The inhibition of ORMDL3 prevents Alzheimer's disease through ferroptosis by PERK/ATF4/HSPA5 pathway by Yankun Shao, Yilin Xu, Huang Di, Xinxiu Shi, Yingying Wang, Hongyu Liu, Lina Song

“…Collectively, these data suggested that ORMDL3 promoted oxidative response and ferroptosis in a model of AD by the PERK/ATF4/HSPA5 pathway, which might be a novel target spot mechanism of ferroptosis in AD and may serve as a regulator of AD‐induced ferroptosis.…”
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Efficacy and Safety of New Oral Anticoagulants versus Warfarin in the Resolution of Atrial Fibrillation with Left Atrial/Left Atrial Appendage Thrombus: A Systematic Review and Met... by Guan-lian Mo, Jing Wen, Yu-yu Ye, Yong-qi Lu, Tian-ming Gan, Ying-jie Yang, Jin-yi Li

“…Background: To compare the efficacy and safety of novel oral anticoagulants (NOACs) and vitamin K antagonists (VKAs) in nonvalvular atrial fibrillation (NVAF) patients with left atrial/left atrial thrombosis through a systematic review and meta-analysis. …”
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Multi-study fMRI outlooks on subcortical BOLD responses in the stop-signal paradigm by Scott Isherwood, Sarah A Kemp, Steven Miletić, Niek Stevenson, Pierre-Louis Bazin, Birte Forstmann

“…We merge five such datasets, using a novel aggregatory method allowing the unification of raw fMRI data across sites. …”
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The relationship between bats and human coronavirus: An exploratory review by Sajal BHATTACHARYA, Shakya SINHA, Rina TILAK, Sugeng Juwono MARDIHUSODO

“…This may eventually cause viral spillover to humans and other ani- mal hosts due to forced proximity, leading to outbreaks of novel diseases. Although bats are considered likely reservoirs of most of the human coronaviruses causing epidemics, yet they cannot be considered as a public health threat as the transmission dynamics is influenced by human behavior/ activities. …”
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Tackling Disinformation Through Public Administration Recommendations –The Czech Experience by Tomáš Svoboda

“…Originality/Value: The topic can be considered novel, given the limited attention it has received in the literature. …”
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A compact and highly isolated integrated 8-port MIMO antenna for sub-6 GHz and mm-wave 5G-NR applications by Manumula Srinubabu, Nuthakki Venkata Rajasekhar

“…The design features a novel elliptical-shaped monopole antenna with a CPW-fed structure for sub-6 GHz frequencies. …”
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Accurate Needle Localization in the Image Frames of Ultrasound Videos by Mohammad I. Daoud, Samira Khraiwesh, Rami Alazrai, Mostafa Z. Ali, Adnan Zayadeen, Sahar Qaadan, Rafiq Ibrahim Alhaddad

“…This paper introduces a novel machine learning-based method to localize the needle in ultrasound videos. …”
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Preparation of Molecularly Imprinted Electrochemical Sensors and Analysis of the Doping of Epinephrine in Equine Blood by Zhao Wang, Yanqi Li, Xiaoxue Xi, Qichao Zou, Yuexing Zhang

“…In this paper, a novel molecularly imprinted polymer membrane modified glassy carbon electrode for electrochemical sensors (MIP-OH-MWCNTs-GCE) for epinephrine (EP) was successfully prepared by a gel-sol method using an optimized functional monomer oligosilsesquioxane-Al₂O₃ sol-ITO composite sol (ITO-POSS-Al₂O₃). …”
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The Discrete Ueda System and Its Fractional Order Version: Chaos, Stabilization and Synchronization by Louiza Diabi, Adel Ouannas, Amel Hioual, Giuseppe Grassi, Shaher Momani

“…This research introduces a novel fractional discrete Ueda system based on <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mi mathvariant="normal">Y</mi></semantics></math></inline-formula>-th Caputo fractional difference and thoroughly investigates its chaotic dynamics via commensurate and incommensurate orders. …”
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