Drug Clues for the Treatment of Fungal Catheter-Related Bloodstream Infection With Antifungal Lock Therapy by Li X, Yu B, Li H, Liu Z, Fu X, Jiao P, Wang L

“…This will facilitate the development of novel treatments for catheter-related fungal infections, thereby improving clinical outcomes.Keywords: antifungal lock therapy, catheter-related bloodstream infections, Candida…”
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High-speed FSO-5G wireless communication system with enhanced loss compensation using high-power EDFA by Stotaw Talbachew Hayle, Hua-Yi Hsu, Chia-Peng Wang, Hai-Han Lu, Jia-Ming Lu, Wei-Wen Hsu, Yu-Chen Chung, Yu-Yao Bai, Kelper Okram

“…Abstract In this paper, we demonstrated a novel bidirectional high-speed transmission system integrating a free-space optical (FSO) communication with a 5G wireless link, utilizing a high-power erbium-doped fibre amplifier (EDFA) for enhanced loss compensation. …”
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Enhancing the photocatalytic performance and chemical durability of AZ31 magnesium alloy by incorporating two types of nanoparticles through plasma electrolytic oxidation by Mosab Kaseem, Abdullah H. Alluhayb, Talitha Tara Thanaa, Arash Fattah-alhosseini, Mohammad Alkaseem

“…The difficulty in achieving a balance between photocatalytic efficiency and chemical robustness has been a barrier to the broad use of MgO as a versatile material, mainly because of its restricted surface activity. To overcome this, a novel surface modification technique is proposed. …”
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Inhibition of zinc dendrite growth by a preferential crystal surface modulation strategy by Weihua Zhou, Junrun Feng, Zhuo Chen, Ziming Wan, Haoyu Feng, Lin Sheng, Zhuo Peng, Wenyuan Zhang, Zhangxiang Hao

“…Compared to traditional methods which stabilize the interface by constructing artificial/in-situ formed interphases, we propose a novel method to selectively adjust the array of stripes on the Zn surface without altering the chemical composition. …”
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Influence of graphene nanoplatelets (GNPs) and aluminum-carbon layered double hydroxides (Al-C LDH) in polypropylene matrix of hybrid composite structures on the microstructure and... by R. Daulath Banu, R. Karunanithi, S. Sivasankaran, B. Subramanian, Abdullah A. Alhomidan

“…In this study, a polypropylene (PP) matrix was reinforced with ultra-fine graphene nanoplatelets (GNPs), aluminum-carbon layered double hydroxides (Al-C LDHs), and calcium carbonate (CaCO3) as hybrid reinforcements, along with polypropylene grafted maleic anhydride (PP-g-MA) compatibilizers to create a novel thermoplastic-based hybrid composite polymer. …”
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Noninvasive in vivo imaging of macrophages: understanding tumor microenvironments and delivery of therapeutics by Prakash Gangadaran, Akanksha Onkar, Ramya Lakshmi Rajendran, Anshika Goenka, Ji Min Oh, Fatima Khan, ArulJothi Kandasamy Nagarajan, Sathish Muthu, Anand Krishnan, Chae Moon Hong, Byeong-Cheol Ahn

“…The integration of multimodal imaging approaches and the continued development of novel contrast agents hold promise for overcoming current limitations and expanding the applications of macrophage imaging. …”
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Nationwide incidence of central retinal artery occlusion in Japan: an exploratory descriptive study using the National Database of Health Insurance Claims (2011–2015) by Hiroshi Tamura, Akitaka Tsujikawa, Masahiro Miyake, Ai Kido, Hanako Ohashi Ikeda, Shusuke Hiragi

“…Aims The latest evidence in the incidence of central retinal artery occlusion (CRAO) is needed to support the development of novel treatments as orphan drugs. However, up-to-date information on the incidence of CRAO in the ageing or aged population is limited. …”
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Clinical and Cost Burden of Primary Sjögren’s Syndrome: Descriptive Analysis Using a US Administrative Claims Database by Sue Perera, Liyuan Ma, Raj Punwaney, Sulabha Ramachandran

“…**Conclusion:** Patients with pSS experience a high disease burden despite treatment. This study provides novel insights in to the extent of the burden on healthcare resources among patients with pSS, in particular for patients with extra-glandular disease manifestations, when compared with sicca-free subjects.…”
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Association between metabolic dysfunction associated steatotic liver disease and gallstones in the US population using propensity score matching by Yingying Zhang, Jingjing Zhang, Dan Yu, Fan Tu, Jun Liu, Bing Han, Binghua Li, Yihang Yuan, Chaobo Chen, Mingli Zhou

“…Abstract The novel diagnostic term Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) requires at least one cardiovascular risk factor for diagnosis. …”
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Pre-injection of exosomes can significantly suppress ovarian cancer growth by activating the immune system in mice by Yuanyuan Wang, Changyi Zhang, Huimin Zeng, Liangliang Wang, Zanhong Wang, Zhiqiang Han

“…But in general, we emphasize that in the case of pre-injection, exosomes have great potential to combat the famous “cold tumor”, ovarian cancer, via targeting omentum and activating anti-tumor immunity, offering a novel avenue for overcoming ovarian cancer.…”
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Genome-wide development of simple sequence repeat (SSR) markers at 2-Mb intervals in lotus (Nelumbo Adans.) by Fengluan Liu, Lin Xi, Naifeng Fu

“…Conclusion These SSR markers, which have a density of 1 SSR marker per 1.76 Mb in this study, will act as a bridge connecting lotus phenotypes with the genome. This work reveals a novel and convenient strategy for developing highly polymorphic SSR markers at any location throughout the lotus genome, and it sheds light on the development of SSR molecular markers in other plant species.…”
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Clinical relevance and druggability of sole reciprocal kinase fusions: A large‐scale study by Jiao Feng, Tonghui Ma, Chunyang Wang, Baoming Wang, Qian Liu, Zhengchuang Liu, Houquan Tao, Zaiyuan Ye

“…Conclusion This inaugural multicenter study introduces a novel algorithm for detecting and treating sole reciprocal fusions in advanced cancers, expanding the patient population potentially amenable to KIs.…”
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Exploring how PRIME-Parkinson care is implemented and whether, how and why it produces change, for who and under what conditions: a protocol for an embedded process evaluation with... by Yoav Ben-Shlomo, Sabi Redwood, Judi Kidger, Emma Tenison, Heather Brant, Emily J Henderson, Fiona Lithander, Katherine Lloyd, Safi Smith

“…Given that this intervention is novel and complex, understanding whether and how the intervention will be acceptable, implementable, cost-effective and scalable across contexts are key questions beyond that of whether ‘it works’. …”
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Balancing Privacy and Utility in Split Learning: An Adversarial Channel Pruning-Based Approach by Afnan Alhindi, Saad Al-Ahmadi, Mohamed Maher Ben Ismail

“…This research introduces a novel privacy-preserving split learning approach that integrates: 1) Adversarial learning and 2) Network channel pruning. …”
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Advanced sleep disorder detection using multi-layered ensemble learning and advanced data balancing techniques by Muhammad Mostafa Monowar, S. M. Nuruzzaman Nobel, Maharin Afroj, Md Abdul Hamid, Md Zia Uddin, Md Mohsin Kabir, M. F. Mridha

“…To address these, we propose a novel coordination model aimed at improving detection accuracy and reliability through a multi-model ensemble approach. …”
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Assessing groundwater quality and suitability in Qatar: Strategic insights for sustainable water management and environmental protection by Sarra Aloui, Adel Zghibi, Annamaria Mazzoni, Ahmad S. Abushaikha, Adel Elomri

“…Suitability for use was assessed using the drinking water quality index (DWQI) and a novel integrated irrigation water quality index (IWQI), constructed upon seven standard indices. …”
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Serum Levels of IL-33 and Correlation with IL-4, IL-17A, and Hypergammaglobulinemia in Patients with Autoimmune Hepatitis by Ma Liang, Zhang Liwen, Zhuang Yun, Ding Yanbo, Chen Jianping

“…Our findings highlight the possible role of the IL-33/sST2 axis in the progression of AIH, opening a new door for developing a novel therapeutic strategy for AIH.…”
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Larvicidal Effect of Breadfruit (Artocarpus altilis) Flower Extract Against Aedes aegypti by Ni Wayan Winianti, Putu Indah Budi Apsari, Ni Kadek Meta Jayanti

“…This study attempted an experiment on the novel invention of a naturally sourced larvacide, specifically breadfruit (Artocarpus atilis) flower extract, against Aedes aegepti. 2. …”
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High Frequency Vibration Fatigue Behavior of Ti6Al4V Fabricated by Wire-Fed Electron Beam Additive Manufacturing Technology by P. Wanjara, J. Gholipour, E. Watanabe, K. Watanabe, T. Sugino, P. Patnaik, F. Sikan, M. Brochu

“…Following foreign object damage (FOD), a decision to repair components using novel additive manufacturing (AM) technologies has good potential to enable cost-effective and efficient solutions for aircraft gas turbine engine maintenance. …”
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The Development of a Large-Area Microchannel Plate Photomultiplier Tube with a Gate Function by Ziyu Liu, Hulin Liu, Ping Chen, Kuinian Li, Yonglin Wei, Luanxuan He, Xinnan Zhao, Wei Zhao, Jinshou Tian

“…To meet the application requirements of neutron detectors, a novel large-area microchannel plate photomultiplier tube with a gate function (G-MCP-PMT) was developed in this study. …”
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