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16281
Mapping global annual urban land cover fractions (2001–2020) derived with multi-objective deep learning
Published 2025-02-01“…Accordingly, this study proposes a novel deep learning unmixing algorithm, Normalized Non-negative Multi-objective Residual T-ConvLSTM (NNMRT) model, with strong encoding and recognition capacities for extracting GAULCF. …”
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16282
Easy Direct Functionalization of 2D MoS2 Applied in Covalent Hybrids with PANI as Dual Blend Supercapacitive Materials
Published 2025-01-01“…These findings demonstrate the potential of similar covalent composites to work as active components for novel, innovative energy storage technologies. At the same time, the successful synthesis marks the efficacy of direct covalent grafting of conductive polymer on the surface of 2D TMDCs for stable functional materials.…”
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16283
Influence of Mesalazine on Ferroptosis-Related Gene Expression in In Vitro Colorectal Cancer Culture
Published 2025-01-01“…Consequently, significant emphasis has been directed towards exploring novel types of cell death, particularly ferroptosis. …”
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16284
Social learning in bonobos: Learning of individual food preferences and copying despite better knowledge
Published 2015-03-01“…The results from experiment 1 followed our predictions and are in accordance with the literature on social learning and social facilitation of acceptance of novel foods. The results from experiment 2 showed that longer exposure was necessary in order to achieve a similar result, indicating that the ‘reverse social learning’ task was more difficult for the bonobos to manage. …”
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16285
Proximity Labeling-Based Identification of MGAT3 Substrates and Revelation of the Tumor-Suppressive Role of Bisecting GlcNAc in Breast Cancer via GLA Degradation
Published 2025-01-01“…Gene ontology analysis revealed that the enriched proteins were predominantly localized in the exosome, endoplasmic reticulum, and Golgi apparatus, consistent with subcellular localization of MGAT3 substrates. Notably, four novel substrates, GOLM2, CCDC134, ASPH, and ERO1A, were confirmed to bear bisecting GlcNAc modification, validating the utility of the proximity labeling method. …”
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16286
Development and validation of a nomogram to predict recurrence in epithelial ovarian cancer using complete blood count and lipid profiles
Published 2025-02-01“…Grade, International Federation of Gynecology and Obstetrics (FIGO) stage, platelet-to-lymphocyte ratio, red blood cell distribution width-coefficient of variation, triglycerides, and human epididymal protein 4 were identified as independent prognostic factors. The novel nomogram displayed a good predictive performance, with a concordance index (C-index) of 0.787 in the training group and 0.807 in the validation group. …”
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16287
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16288
Exploring Clec9a in dendritic cell-based tumor immunotherapy for molecular insights and therapeutic potentials
Published 2025-02-01“…Additionally, this review explores the potential of Clec9a-targeted approaches to enhance the immunogenicity of tumor vaccines and addresses the utilization of Clec9a as a delivery target for specific agonists (such as STING agonists and αGC) to enhance their therapeutic effects. This novel approach leverages Clec9a’s capacity to improve the precision and efficacy of these immunomodulatory molecules in tumor treatment. …”
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16289
New Resinogalea species from Araucaria araucana resin in Chile and reclassification of the genus in the Cryptocaliciomycetidae
Published 2023-08-01“…The recent emergence of a novel canker disease on A. araucana has emphasised the importance of fungi associated with these iconic trees and has resulted in the discovery of various new species. …”
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16290
Accurate pulse time distribution determination using MLEM algorithm in integral experiments
Published 2025-02-01“…This study presents a novel approach to accurately determine pulse time distribution in integral experiments conducted with pulsed accelerators. …”
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16291
Case report: Successful therapy with recombinant human vascular endostatin in an elderly man with colon telangiectasia and idiopathic thrombocytopenic purpura
Published 2025-01-01“…In this case, a vascular endothelial growth factor (VEGF) inhibitor was successfully applied to treat a refractory and rare GI bleeding, which may offer a novel therapeutic approach for similar cases.…”
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16292
Forecasting epidemic spread of SARS-CoV-2 using ARIMA model (Case study: Iran)
Published 2020-08-01“…Currently, the pandemic caused by a novel coronavirus, namely severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is one of the most serious issues worldwide. …”
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16293
CausalXtract, a flexible pipeline to extract causal effects from live-cell time-lapse imaging data
Published 2025-01-01“…We showcase the use of CausalXtract to uncover novel causal effects in a tumor-on-chip cellular ecosystem under therapeutically relevant conditions. …”
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16294
A qualitative study exploring depressed participants’ experiences of receiving Augmented Depression Therapy (ADepT)
Published 2025-02-01“…Objectives The current study aimed to explore participants’ views on the acceptability, impact and mechanisms of change of Augmented Depression Therapy (ADepT), a novel wellbeing-focused and recovery-oriented psychological therapy for depression.Design A semi-structured qualitative interview design was used, with data analysed using the framework approach.Participants 20 participants with anhedonic depression who had received up to 20 sessions of ADepT, sampled from a pilot randomised controlled trial of ADepT versus Cognitive Behavioural Therapy (CBT).Setting A primary care psychological therapy clinic in Devon, UK, with interviews occurring between May 2018 and February 2020.Results Participants found the wellbeing focus of ADepT acceptable. …”
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16295
The Role of Inflammatory Cytokines and lncRNAs in the Pathogenesis of Atherosclerosis and Other Inflammatory Diseases: Focus on Sarcoidosis and Alzheimer’s Disease
Published 2025-01-01“…Materials and Methods Through a systematic review of recent studies, we identify key pathways and discuss translational implications for novel interventions. Description of the State of Knowledge Inflammatory cytokines, including interleukin-1β (IL-1β), tumor necrosis factor-α (TNF-α), and interleukin-6 (IL-6), orchestrate immune responses that exacerbate endothelial dysfunction, foam cell formation, and plaque instability. …”
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16296
Elucidating the relationship between burnout and sleep disturbances among firefighters: a network analysis
Published 2025-01-01“…Network analysis offers novel perspectives for understanding the interactions of psychopathological variables. …”
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16297
circHUWE1 Exerts an Oncogenic Role in Inducing DDP-Resistant NSCLC Progression Depending on the Regulation of miR-34a-5p/TNFAIP8
Published 2021-01-01“…Conclusion. circHUWE1 functioned as a promoter in DDP-resistant NSCLC by interaction with miR-34a-5p-TNFAIP8 networks, providing novel insight into DDP-resistant NSCLC diagnosis and treatment.…”
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16298
EN The combined effect of heating zone length and inclination angle on start-up, transient and operational characteristics of pulsating heat pipe
Published 2024-09-01“…Pulsating heat pipes (PHP) are novel heat transfer devices which have wide prospects of application in energy, refrigeration, cryogenic systems and electronics cooling because of simple design and high efficiency of heat transfer. …”
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16299
Innovative Equation for Determining the Geochemical Background Values of Chromium Based on Major Components in Rock–Soil–Sediment Systems
Published 2024-12-01“…In this study, we introduce a novel equation to calculate the geochemical background value of Cr, based on the premise that major elements can effectively delineate the geochemical background for trace elements. …”
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16300
Distal Radial Artery Access in comparison to Forearm Radial Artery Access for Cardiac Catheterization: A Randomized Controlled Trial (DARFORA Trial)
Published 2022-01-01“…The distal radial artery (DRA) access site has recently emerged as a novel technique in cardiac procedures. Objectives. …”
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