Humanising nanotoxicology: replacement of animal-derived products in the application of integrated approaches to testing and assessment of nanomaterial inhalation hazard by Roma Fraser, Keira Campbell, Pawel Pokorski, Eve MacKinnon, Katie McAllister, Karla B. Neves, Fiona Murphy

“…This has prompted the design of Novel Approach Methods (NAMs) to streamline risk assessment and predict human hazards without relying on animal testing. …”
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Solution-Based Ultraviolet Photodiode with ZnO Nanoparticle/Poly(3,4-Ethylenedioxythiophene) Polystyrene Sulfonate Heterojunction and Negative Capacitance by Jin Li, Xin Chang, Shunpu Li, Yi Zhang, Daping Chu

“…The demand for high-performance UV detectors with low cost and easy fabrication drives the development of novel materials and structures such as wide-bandgap semiconductors, polymers, photodiodes, and phototransistors. …”
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Climate Impact on Evapotranspiration in the Yellow River Basin: Interpretable Forecasting with Advanced Time Series Models and Explainable AI by Sheheryar Khan, Huiliang Wang, Umer Nauman, Rabia Dars, Muhammad Waseem Boota, Zening Wu

“…This study also introduces novel algorithms for Explainable AI (XAI) and SHAP (SHapley Additive exPlanations), enhancing the interpretability of model predictions and improving understanding of how climate variables affect ET. …”
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Flanking monomer repeats define lower context complexity of sites containing single nucleotide polymorphisms in the human genome by N. S. Safronova, M. P. Ponomarenko, I. I. Abnizova, G. V. Orlova, I. V. Chadaeva, Y. L. Orlov

“…We have developed and applied novel statistical computational methods to analyze genetic text based on its complexity. …”
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Oligomeric procyanidins combined with Parabacteroides distasonis ameliorate high-fat diet-induced atherosclerosis by regulating lipid metabolism, inflammation reaction and bile aci... by Mingjuan Xu, Cheng Lü, Yiqing Hu, Mo Zhang, Jinxin Shen, Chunyi Liu, Qun Lu, Rui Liu

“…In summary, PPC attenuated HFD-induced AS in ApoE-/- mice, which provides new insights into the design of novel and efficient anti-atherosclerotic strategies to prevent AS based on probiotics and prebiotics.…”
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ISU201 Enhances the Resolution of Airway Inflammation in a Mouse Model of an Acute Exacerbation of Asthma by Yuka Hiroshima, Linda Garthwaite, Kenneth Hsu, Hyouna Yoo, Sang-Ho Park, Carolyn L. Geczy, Rakesh K. Kumar, Cristan Herbert

“…Using a murine model of an acute exacerbation of asthma, we assessed the ability of ISU201, a novel protein drug, to suppress the inflammatory response when administered after induction of an exacerbation. …”
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Multifaceted properties of Ni and Zn codoped MgO nanoparticles by A. Chithra Mohan, A. Athira, Bindu P. Nair, G. Sivasubramanian, K. M. Sreekanth, Gopinathan Anoop, Sreeprasanth Pulinthanathu Sree, K. M. Sreedhar

“…Abstract Recent advancements in material science have aimed to create novel nanomaterials with unique properties and potential applications across diverse domains. …”
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The OXT rs6133010 variant modulates susceptibility to psychiatric symptoms during withdrawal in patients with alcohol dependence by Guanghui Shen, Wei Wang, Yuyu Wu, Xinguang Luo, Kexin Wang, Yu-Hsin Chen, Yimin Kang, Yanlong Liu, Fan Wang, Li Chen

“…Conclusion This study presents novel evidence that OXT rs6133010 specifically modulates psychiatric symptoms in AD. …”
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Ultrasound-assisted extraction of phenolic compounds from ear mushrooms (Auricularia auricula-judae): Assessing composition and antioxidant activity during fruiting body developmen... by Albert Nugraha, Asadin Briliantama, M Umar Harun, Li Sing-Chung, Chin Xuan Tan, Vuanghao Lim, Amir Husni, Widiastuti Setyaningsih

“…This study introduces a novel ultrasound-assisted extraction technique to quantify phenolic compounds and assess antioxidant activity in ear mushrooms. …”
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Prognostic Utility of Prechemoradiotherapy Albumin-to-Alkaline Phosphatase Ratio in Unresectable Locally Advanced Pancreatic Carcinoma Patients by Veysel Haksoyler, Erkan Topkan

“…The present results proposed that the pretreatment AAPR<0.46 was a novel independent indicator of adverse PFS and OS in unresectable LAPAC patients undergoing definitive CCRT.…”
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Exploration of Digital Twin Design Mechanism of the Deep in Situ Rock Insulation Coring Device by Bo Yu, Heping Xie, Ling Chen, Wu Zhao, Zhiqiang He

“…The exploration of the novel design model combined digital twin technology with innovative design theory. …”
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Identification of Ferroptosis-Associated Long Noncoding RNA Prognostic Model and Tumor Immune Microenvironment in Thyroid Cancer by Yongjian Lin, Fu Gan, Xiaoyu He, Huachu Deng, Yong Li

“…Conclusion. We constructed a novel ferroptosis-associated lncRNA nomogram that could highly predict the prognosis of TC patients. …”
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Elliptical FRP-Concrete-Steel Double-Skin Tubular Columns under Monotonic Axial Compression by Bing Zhang, Gui-Sen Feng, Yan-Lei Wang, Cong-Cong Lai, Chen-Chen Wang, Xia-Min Hu

“…Hybrid FRP-concrete-steel double-skin tubular columns (hybrid DSTCs) are a novel form of hollow columns consisting of an outer FRP tube, an inner steel tube, and an annular layer of concrete between the two tubes. …”
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New Perspectives on Canned Fish Quality and Safety on the Road to Sustainability by Antónia Juliana Pais-Costa, António Marques, Helena Oliveira, Amparo Gonçalves, Carolina Camacho, Helga Coelho Augusto, Maria Leonor Nunes

“…It also examines emerging trends in product development, particularly novel formulations aimed at optimizing nutritional value while maintaining safety standards without compromising sustainability. …”
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Increased Depth of Cellular Imaging in the Intact Lung Using Far-Red and Near-Infrared Fluorescent Probes by Abu-Bakr Al-Mehdi, Mita Patel, Abu Haroon, Darla Reed, B. Ohlsson-Wilhelm, K. Muirhead, Brian D. Gray

“…The maximum depth of cell visualization was significantly improved with the novel dyes (36.4±1 μm from the pleural surface) compared with GFP (30.1±0.5 μm; p=0.01; n=50). …”
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Facies-Constrained Kriging Interpolation Method for Parameter Modeling by Zhenbo Nie, Bo Feng, Huazhong Wang, Chengliang Wu, Rongwei Xu, Chao Ning

“…This article introduces seismic facies information into the Kriging method and proposes a novel parameter modeling method named the facies-constrained Kriging (FC-Kriging) method. …”
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NF-κB-94ins/del ATTG Genotype Contributes to the Susceptibility and Imbalanced Th17 Cells in Patients with Immune Thrombocytopenia by Jie Yu, Mingqiang Hua, Xueyun Zhao, Rui Wang, Chaoqing Zhong, Chen Zhang, Ruiqing Wang, Guosheng Li, Na He, Ming Hou, Daoxin Ma

“…The NF-κB-94ins/del ATTG genotype might serve as a novel biomarker and potential target for ITP.…”
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Diagnosis of Coxiella burnetii endocarditis by using nanopore targeted sequencing: a case report by Xinsheng Yan, Qimei Wei, Tingting Liu, Dong Wang, Zhenlu Zhang

“…Conclusion This case study demonstrates the accurate diagnosis and treatment of C. burnetii endocarditis through NTS analysis of blood samples. As a novel technology, NTS may play an important role in the diagnosis of culture-negative infections caused by unidentified pathogens.…”
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Development of Modified-Release Diclofenac Sodium Capsules Using Blends of Pectin-Clay Multiparticulate Hybrid Systems as Release Retardants by Ofosua Adi-Dako, Frederick William Akuffo Owusu, Isaac Yaw Attah, Doris Kumadoh, Prince George Acquah Jnr, Issaka Nelson, Nii Odartey Hutton-Mills, Karen Yaa Yeboaa Obese, Joseph Adusei Sarkodie, Benoit Banga N’guessan, Awo Afi Kwapong, Christina Osei-Asare, Emmanuel Adase, Mary-Ann Archer

“…A combination of inorganic and organic hybrid systems is of high research interest as they provide novel hybrid systems for the improvement of existing properties, overcoming limitations of the parent materials, and for the optimization of their controlled release potential. …”
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Cell-associated flagella enhance the protection conferred by mucosally-administered attenuated Salmonella Paratyphi A vaccines. by Orit Gat, James E Galen, Sharon Tennant, Raphael Simon, William C Blackwelder, David J Silverman, Marcela F Pasetti, Myron M Levine

“…The virulence of the resulting isogenic strains was examined using a novel mouse LD(50) model to accommodate the human-host restricted S. …”
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