Dual-hybrid intrusion detection system to detect False Data Injection in smart grids. by Saad Hammood Mohammed, Mandeep S Jit Singh, Abdulmajeed Al-Jumaily, Mohammad Tariqul Islam, Md Shabiul Islam, Abdulmajeed M Alenezi, Mohamed S Soliman

“…This paper addresses this gap by proposing a novel IDS that utilizes hybrid feature selection and deep learning classifiers to detect FDIAs in smart grids. …”
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Effects of Retinol, Natural Pea Peptide and Antioxidant Blend in a Topical Formulation: In Vitro and Clinical Evidence by Brian Cook, Melanie Riggs, K. C. Holley, Helen Knaggs, Ganesh Diwakar, Edwin D. Lephart

“…The present study assessed the effectiveness of a novel topical formulation, referred to as retinol topical formulation (RTF), to improve the quality of skin health. …”
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Calpain 2 regulates IL-1α secretion and inhibits tumor development via modulating calpain 1 expression in the tumor microenvironment by Zuhairah Binte Hanafi, Yu Mei, Huey Yee Teo, Ying Zhu, Chew Chin Yong Lionel, Jing Wen Chiu, Jinhua Lu, Haiyan Liu

“…Collectively, these results suggest that calpain 2 modulates calpain 1 expression, and therefore IL-1α secretion through the induction of FoxO3, offering novel potential therapeutic targets for cancer treatment.…”
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Comparison of different developmental stages of jujube (Ziziphus jujuba) fruit and identification of Hub genes by Li Yalan, Ren Tian, Qu Siyu, Hao Qing, Fan Dingyu, Alimire Alimu

“…Based on the results, a total of 3448 unannotated novel genes were identified. The number of DEGs in the four group comparisons WM vs FE, ER vs WM, FR vs ER and FR vs FE groups were 1576, 8561, 1073 and 7884 DEGs, respectively, and mainly involved in biological processes such as stimulation, defence, immunity, ADP binding, DNA-binding transcription factor activity, secondary active transmembrane transporter activity, etc. …”
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Extracellular domain of TREM2 possess two distinct ligand recognition sites: Insights from machine-learning guided docking and all-atoms molecular dynamics simulations by Sarbani Mishra, Preety Sthutika Swain, Sanghamitra Pati, Budheswar Dehury

“…Our knowledge-based and machine-learning guided docking and physics-based simulations study unveils deep insights into the endogenous ligand recognition by the positive surface ligand binding site and distant core site pave the way for exploration of other small molecules towards development of novel therapeutics against Alzheimer's disease.…”
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Immunobridging Trials: An Important Tool to Protect Vulnerable and Immunocompromised Patients Against Evolving Pathogens by Pedro Cruz, Jie Min Lam, Jehad Abdalla, Samira Bell, Jola Bytyci, Tal Brosh-Nissimov, John Gill, Ghady Haidar, Michael Hoerger, Yasmin Maor, Antonio Pagliuca, Francois Raffi, Ffion Samuels, Dorry Segev, Yuxin Ying, Lennard Y. W. Lee

“…Recently, this method has also been employed to authorise novel drugs, such as COVID-19 vaccines, and this article explores the concepts behind immunobridging trials, their advantages, issues, and significance in the context of COVID-19 and other infectious diseases. …”
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Structural insights into how Cas9 targets nucleosomes by Reina Nagamura, Tomoya Kujirai, Junko Kato, Yutaro Shuto, Tsukasa Kusakizako, Hisato Hirano, Masaki Endo, Seiichi Toki, Hiroaki Saika, Hitoshi Kurumizaka, Osamu Nureki

“…These findings will contribute to the development of novel genome editing tools in chromatin.…”
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Hydrogen Sulfide Increases Nitric Oxide Production and Subsequent S-Nitrosylation in Endothelial Cells by Ping-Ho Chen, Yaw-Syan Fu, Yun-Ming Wang, Kun-Han Yang, Danny Ling Wang, Bin Huang

“…Elevated gaseous NO levels were observed by a novel and specific fluorescent probe, 5-amino-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid methyl ester (FA-OMe), and quantified by flow cytometry. …”
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Spatiotemporal patterns of annual clear-cutting distribution in tropical and subtropical regions of China with time series Landsat and CCDC by Mingxing Zhou, Guiying Li, Dengsheng Lu, Cong Xu, Zhipeng Li, Dengqiu Li

“…This research leveraged dense time-series Landsat images (1986–2022) and a novel approach combining Continuous Change Detection and Classification (CCDC) with Random Forest to produce the first annual 30 m resolution clear-cutting map for the China’s subtropical and tropical regions. …”
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The Therapeutic Targets of miRNA in Hepatic Cancer Stem Cells by Sabrina Bimonte, Maddalena Leongito, Antonio Barbieri, Vitale del Vecchio, Michela Falco, Aldo Giudice, Raffaele Palaia, Vittorio Albino, Raimondo Di Giacomo, Antonella Petrillo, Vincenza Granata, Francesco Izzo

“…In this review, we synthesize the latest findings on therapeutic regulation of HCSCs by miRNAs, in order to highlight the perspective of novel miRNA-based anticancer therapies for HCC treatment.…”
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Rationale and design of the CardioMEMS Post‐Market Multinational Clinical Study: COAST by Martin R. Cowie, Pascal deGroote, Scott McKenzie, Marie‐Elena Brett, Philip B. Adamson, the CardioMEMS Post‐Market Study Investigators

“…The results may support the more widespread implementation of this novel clinical management approach.…”
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Non-linear enhancement of ultrafast X-ray diffraction through transient resonances by Stephan Kuschel, Phay J. Ho, Andre Al Haddad, Felix F. Zimmermann, Leonie Flueckiger, Matthew R. Ware, Joseph Duris, James P. MacArthur, Alberto Lutman, Ming-Fu Lin, Xiang Li, Kazutaka Nakahara, Jeff W. Aldrich, Peter Walter, Linda Young, Christoph Bostedt, Agostino Marinelli, Tais Gorkhover

“…Our experimental results and Monte Carlo simulations suggest that transient resonances can increase ionic scattering cross sections significantly beyond literature values. This provides a novel avenue towards substantial improvement of the spatial resolution in CDI in combination with sub-femtosecond temporal precision at the nanoscale.…”
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NRBF2 plays a crucial role in the acquisition process of learning and memory, independent of the Vps34 complex by Songfen Wu, Songfen Wu, Songfen Wu, Haicai Zhuang, Haicai Zhuang, Haicai Zhuang, Xidan Zhou, Kuan Li, Kuan Li, Kuan Li

“…Our results suggested that NRBF2 deletion impaired memory acquisition through an autophagy-independent pathway and provided novel insights into the role of NRBF2 in the central nervous system.DiscussionThis study offer new insights into the role of NRBF2 and highlight the potential of targeting NRBF2 as a therapeutic strategy for addressing cognitive deficits associated with various disorders.…”
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Research trends and frontiers in rehabilitation after total knee arthroplasty: based on bibliometric and visualization analysis by Runkai Zhao, Haichao Ren, Pengcheng Li, Menglin Fan, Runzhi Zhao, Te Liu, Yan Wang, Quanbo Ji, Guoqiang Zhang

“…Reference and keyword analyses suggest that remote or home-based rehabilitation, the development of novel prehabilitation techniques, and pain management hold significant research potential, constituting current research hotspots. …”
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A Sensitive, Specific and Fast Electrochemical‐based Nanobiosensor Diagnostic for Xanthomonas albilineans, the Cause of Sugarcane Leaf Scald Disease by Moutoshi Chakraborty, Shamsul Arafin Bhuiyan, Simon Strachan, Muhammad J.A. Shiddiky, Nam‐Trung Nguyen, Narshone Soda, Rebecca Ford

“…This study proposes a novel electrochemical (EC)‐approach, that is relatively easy to use and less expensive to detect Xalb DNA in LS‐infected sugarcane leaves, meristematic tissue, and xylem sap samples. …”
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Fluidization of fine coal particles in an ultrasound enhanced gas-solid fluidized bed by Sayuri Naicker, Neeraj Kuarsingh, Milan Carsky, David Lokhat

“…The reduction in minimum fluidization velocity shows promise for reduced energy consumption, and increased production throughput, of the fine coal particle processing industry. Overall the novel application of ultrasound improved the quality and operability of the fluidization of fine coal particles.…”
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Multi‐Wound Classification: Exploring Image Enhancement and Deep Learning Techniques by Prince Odame, Maxwell Mawube Ahiamadzor, Nana Kwaku Baah Derkyi, Kofi Agyekum Boateng, Kelvin Sarfo‐Acheampong, Eric Tutu Tchao, Andrew Selasi Agbemenu, Henry Nunoo‐Mensah, Dorothy Araba Yakoba Agyapong, Jerry John Kponyo

“…The approaches used included Contrast Limited Adaptive Histogram Equalization (CLAHE) with machine and deep learning models, Discrete Wavelet Transformations (DWT) with a novel Gated Wavelet Convolutional Neural Network (CNN) model, and FixCaps, an improved version of Capsule Networks utilizing Convolutional Block Attention Module (CBAM) to reduce spatial information loss. …”
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Improvement of Presbyopia, Dry Eye, Intraocular Pressure, and Near Vision Through Cassiae Tea Consumption by Mei Fan, Jen-Lin Hung, Shao-Huan Hung, Li-Chai Chen, Chi-Ting Horng

“…<i>Background and Objectives</i>: This study aimed to illustrate a novel method for improving presbyopia by drinking cassiae tea. …”
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Rapidly In Situ Forming Platelet-Rich Plasma Gel Enhances Angiogenic Responses and Augments Early Wound Healing after Open Abdomen by Bo Zhou, Jianan Ren, Chao Ding, Yin Wu, Dong Hu, Guosheng Gu, Jieshou Li

“…Rapidly in situ forming platelet-rich plasma gel promoted remarkable neovascularization and early wound healing after open abdomen and may lead to novel and effective treatments for open abdominal wounds.…”
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Reduced‐Order Probabilistic Emulation of Physics‐Based Ring Current Models: Application to RAM‐SCB Particle Flux by Alfredo A. Cruz, Rashmi Siddalingappa, Piyush M. Mehta, Steven K. Morley, Humberto C. Godinez, Vania K. Jordanova

“…The probabilistic emulator is built upon the methodology developed by Licata and Mehta (2023), https://doi.org/10.1029/2022sw003345. A novel discrete sampling is used to identify 30 simulation periods over 20 years of solar and geomagnetic activity. …”
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