Autophagy: An Overview of Molecular Mechanisms and Its Therapeutic Implications for Health and Disease by Hourolein Arab, Mohammad Reza Mofid, Mahboube Rahmati, Elahe Gharehkhani, Armin Mokhtariye, Mohammad Shokrzadeh

“…This review provides a comprehensive analysis of the mechanisms and functions of autophagy, exploring its association with various human diseases. It presents a novel perspective on the potential clinical applications of autophagy, highlighting its role in the development of therapeutic strategies and deepening our understanding of this essential cellular process.…”
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Personalized medicine: An alternative for cancer treatment by Devendra Singh, Vinay Kumar Dhiman, Minakshi Pandey, Vivek Kumar Dhiman, Avinash Sharma, Himanshu Pandey, Sunil Kumar Verma, Rajeev Pandey

“…Ongoing research seeks to detect gene modifications in diverse cancer types, produce novel diagnostic tools, and develop treatments that particularly target these genetic changes. …”
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The genomes of Scedosporium between environmental challenges and opportunism by Francesco Venice, Federica Spina, Domenico Davolos, Stefano Ghignone, Giovanna Cristina Varese

“…However, unlike other fungal pathogens, little is known about the genome evolution of these organisms. We sequenced two novel genomes of Scedosporium aurantiacum and Scedosporium minutisporum isolated from extreme, strongly anthropized environments. …”
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STFCropNet: A Spatiotemporal Fusion Network for Crop Classification in Multiresolution Remote Sensing Images by Wei Wu, Yapeng Liu, Kun Li, Haiping Yang, Liao Yang, Zuohui Chen

“…To address the issue, we propose a novel approach termed spatiotemporal fusion-based crop classification network (STFCropNet), which integrates high-resolution (HR) images with medium-resolution time-series (TS) images. …”
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Extracellular Vesicles and Tunnelling Nanotubes as Mediators of Prostate Cancer Intercellular Communication by Jessica K. Heatlie, Joanna Lazniewska, Courtney R. Moore, Ian R. D. Johnson, Bukuru D. Nturubika, Ruth Williams, Mark P. Ward, John J. O’Leary, Lisa M. Butler, Doug A. Brooks

“…Overexpression assays of a newly designed androgen receptor (AR) plasmid revealed its novel localization in PCa cellular vesicles, which were also transferred to neighbouring cells. …”
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Molecular Mechanisms and Therapeutic Prospects of Immunotherapy and Targeted Therapy in Primary Central Nervous System Lymphoma by Lin Zhong MM, Anqing Lu MB, Xiyue Lu MM, Xiaoyin Liu MD, Lujia Cao MM, Shihong Zhu MM, SiJun Diao MM, Xu Cheng MM, Hongwei Wu MB, Jing Chen MD

“…These therapies have paved the way for novel treatment strategies in PCNSL, representing a highly promising field. …”
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Low Profile Planar Inverted-L Antenna (PILA) for UHF RFID Tag on Signal Absorption and Reflection Surfaces by Minh-Tan Nguyen, Yi-Fang Lin, Chien-Hung Chen, Hoang-Son Luong, Hua-Ming Chen

“…In this study, we propose a novel design incorporating six Planar Inverted-L Antennas (PILAs) to miniaturize Ultra-High Frequency Radio Frequency Identification (UHF-RFID) tags, thereby enhancing tag efficiency when mounted on various conductive surfaces. …”
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Comparative Study on the Evolution of Airflow Temperature and Valid Ventilation Distance Under Different Cooling Strategies in High-Temperature Tunnels for Mining Thermal Energy by Fangchao Kang, Jinlong Men, Binbin Qin, Guoxi Sun, Ruzhen Chen, Weikang Zhang, Jiamei Chen, Zhenpeng Ye

“…In this paper, we introduce a novel cooling strategy that integrates thermal insulation layers and heat exchangers aligned along the tunnel axis (TIL-HE strategy). …”
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4-Methoxycarbonyl Curcumin: A Unique Inhibitor of Both Inflammatory Mediators and Periodontal Inflammation by Ying Gu, Hsi-Ming Lee, Nicole Napolitano, McKenzie Clemens, Yazhou Zhang, Timo Sorsa, Yu Zhang, Francis Johnson, Lorne M. Golub

“…In the current study, we demonstrate that a novel CMC (CMC 2.5: 4-methoxycarbonyl curcumin) has significant inhibitory effects, better than the parent compound curcumin, on proinflammatory cytokines and MMPs in in vitro, in cell culture, and in an animal model of periodontal inflammation. …”
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Quad-Band 3D Rectenna Array for Ambient RF Energy Harvesting by Fatima Khalid, Warda Saeed, Nosherwan Shoaib, Muhammad U. Khan, Hammad M. Cheema

“…In order to maintain stable rectenna output at varying input power levels and load resistances, a novel transmission line based matching network using closed form equations is proposed. …”
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Quantitative Evaluation of Top Coal Caving Methods at the Working Face of Extra-Thick Coal Seams Based on the Random Medium Theory by Shi Jiulin, Zhang Quntao, Gao Xiaojin, Xue Jisheng

“…Accordingly, the optimal caving interval and caving sequences are determined, and a novel interval symmetrical coal caving method is proposed. …”
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An Analysis of Lexical Coherence in Fereydoun Tavallali’s Al-Tafasil from the perspective of functional Linguistics by Gholamreza Salimi, Zahra Rafie, Alireza Biaban Navard Sarvestani

“…He has employed word repetition to enhance the coherence of the overall context in a novel way and has also used Saj' (rhymed prose) to create coherence and cohesion among successive sentences. …”
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An automated privacy-preserving self-supervised classification of COVID-19 from lung CT scan images minimizing the requirements of large data annotation by Sadia Sultana Chowa, Md Rahad Islam Bhuiyan, Mst. Sazia Tahosin, Asif Karim, Sidratul Montaha, Md. Mehedi Hassan, Mohd Asif Shah, Sami Azam

“…Abstract This study presents a novel privacy-preserving self-supervised (SSL) framework for COVID-19 classification from lung CT scans, utilizing federated learning (FL) enhanced with Paillier homomorphic encryption (PHE) to prevent third-party attacks during training. …”
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Experimental Study of H-Shaped Honeycombed Stub Columns with Rectangular Concrete-Filled Steel Tube Flanges Subjected to Axial Load by Jing Ji, Maomao Yang, Zhichao Xu, Liangqin Jiang, Huayu Song

“…Finally, several design guidelines are suggested, which can provide a foundation for the popularization and application of this kind of novel composite column in practical engineering projects.…”
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Hydrostatic Pressure Modulates Intervertebral Disc Cell Survival and Extracellular Matrix Homeostasis via Regulating Hippo-YAP/TAZ Pathway by Yiyang Wang, Baoshuai Bai, Yanzhu Hu, Haoming Wang, Ningyuan Liu, Yibo Li, Pei Li, Guangdong Zhou, Qiang Zhou

“…The current study is aimed at investigating the role of dynamic hydrostatic pressure in regulating biological behavior of the notochordal nucleus pulposus (NP) and fibrocartilaginous inner annulus fibrosus (AF) and its possible mechanism using our novel self-developed hydrostatic pressure bioreactor. …”
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Romidepsin Promotes Osteogenic and Adipocytic Differentiation of Human Mesenchymal Stem Cells through Inhibition of Histondeacetylase Activity by Dalia Ali, Elna P. Chalisserry, Muthurangan Manikandan, Rimi Hamam, Musaad Alfayez, Moustapha Kassem, Abdullah Aldahmash, Nehad M. Alajez

“…Our data indicated that romidepsin is a novel in vitro modulator of adipocytic and osteoblastic differentiation of BMSCs.…”
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Enhancing heat exchanger design using autoencoder model for predicting efficiency and cost in chemical processing by Manimegalai T, Anitha Gopalan, Vanmathi Murugesan, Jayant Giri, Praveen Barmavatu, Praveenkumar T R, Dinesh Mavaluru, Rafath Samrin

“…In this study, the research proposes a novel approach to enhance heat exchanger design using an autoencoder model for predicting both efficiency and cost. …”
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Analysis of differentially expressed genes in hypertension and hypertensive cerebral hemorrhage via RNA-sequencing by Hongwu Qi, Min Qiao, Yansong Liu, Weijun Zeng, Lizhao Zhang, Hongjun Guo

“…Our study may make a contribution for the understanding of the specific mechanisms of HT and HCH and representing a potential novel strategy for HT and HCH treatment.…”
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Epsin3 promotes non-small cell lung cancer progression via modulating EGFR stability by Huiling Su, Jie Shen, Chenzi Gao, Yue Zhao, Wanyu Deng, Bo Qin, Xin Zhang, Juan Lai, Qian Wang, Jie Dou, Min Guo

“…Targeting EPN3 could offer a novel therapeutic strategy to overcome drug resistance in EGFR-driven NSCLC.…”
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Cryopreservation of Bone Marrow Mononuclear Cells Alters Their Viability and Subpopulation Composition but Not Their Treatment Effects in a Rodent Stroke Model by Bing Yang, Kaushik Parsha, Krystal Schaar, Nikunj Satani, Xiaopei Xi, Jaroslaw Aronowski, Sean I. Savitz

“…The systemic administration of autologous bone marrow (BM) derived mononuclear cells (MNCs) is under investigation as a novel therapeutic modality for the treatment of ischemic stroke. …”
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