Measuring Visual Function Using the MultiQuity System: Comparison with an Established Device by Patrycja Smolarek-Kasprzak, John M. Nolan, Stephen Beatty, Jessica Dennison, Kwadwo Owusu Akuffo, Robert Kuchling, Jim Stack, Graham O’Regan

“…Corrected distance VA (CDVA) and CS were measured in the right eye of 73 subjects, on an established system (Thompson Xpert) and a novel system (MiQ 720). Regression was used to convert MiQ scores into the Thompson scale. …”
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Maytansinoids in cancer therapy: advancements in antibody–drug conjugates and nanotechnology-enhanced drug delivery systems by Matteo Perra, Ines Castangia, Matteo Aroffu, Federica Fulgheri, Rita Abi-Rached, Maria Letizia Manca, Hernán Cortés, María Luisa Del Prado-Audelo, Carla Nomura-Contreras, Alejandra Romero-Montero, Dietrich Büsselberg, Gerardo Leyva-Gómez, Javad Sharifi-Rad, Daniela Calina

“…Ongoing research aims to enhance the safety and efficacy of AMCs, integrate nanotechnology for drug delivery, and identify novel therapeutic targets. These advancements hold potential to transform maytansinoid-based cancer treatments in the future.…”
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Development of Nutrient-Rich Injera Using Amaranthus Leaf/Grain and Teff Flours: A Study on Nutritional Value, Sensory Characteristics, and Storage Stability by Betelhem Abera, Ramesh Duraisamy, Tewodros Birhanu, Beyene Gurbo, Ketemaw Salelign

“…Furthermore, lower proportions of Amaranthus grain flour (2, 4, and 6 g blending) and leaf flour (2–10 g blending) significantly extended the storage period of blended flatbread up to 6–7 days, where higher proportions of Amaranthus grain (8 and 10 g blending) are expected to preserve the flatbread Injera up to 9–10 days, surpassing the 3–4 days of the control (100 g teff flour). Therefore, novel teff–Amaranthus blended food can be produced by means of a cost-effective and easy-to-produce new integrated teff–Amaranthus blended food that can enhance the nutritional value and shelf life of the existing teff Injera.…”
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Anatomical and physiological contributions of nasal turbinate vessels and lymphatics to the pathogenesis of nasal congestion in recurrent headaches: a pilot study by Jacob M. Chmielecki, Aishwarya Vemula, Joyce G. Schwartz, Jonathan A. Gelfond, William T. Phillips

“…This research highlights a novel diagnostic use of the whole-body blood pool scan for the assessment of nasal turbinate vasodilation as well as a possible new target for the treatment of recurrent headaches.…”
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Adaptive modification of antiviral defense systems in microbial community under Cr-induced stress by Dan Huang, Jingqiu Liao, Jose Luis Balcazar, Mao Ye, Ruonan Wu, Dongsheng Wang, Pedro J. J. Alvarez, Pingfeng Yu

“…These findings advance our understanding of microbial adaptation in stressful environments and may inspire novel approaches for microbiome manipulation and bioremediation. …”
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Predictive Ability of Visit-to-Visit Variability of HbA1c Measurements for the Development of Diabetic Kidney Disease: A Retrospective Longitudinal Observational Study by Yunyi Yan, Nozomi Kondo, Kentaro Oniki, Hiroshi Watanabe, Tadashi Imafuku, Yuki Sakamoto, Takuro Shigaki, Akari Maruyama, Hitomi Nakazawa, Tetsuya Kaneko, Ayami Morita, Akira Yoshida, Hitoshi Maeda, Toru Maruyama, Hideaki Jinnouchi, Junji Saruwatari

“…Visit-to-visit variability of HbA1c was an independent risk factor of microalbuminuria in association with oxidative stress among type 2 diabetes mellitus patients. HbA1c-AUC, a novel index of HbA1c variability, may be a potent prognostic indicator in predicting the risk of microalbuminuria.…”
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Iranian Pediatric COVID-19 Epidemiology and Clinical Characteristics by Shahnaz Armin, Mohammadreza Mirkarimi, Zahra Pourmoghaddas, Marjan Tariverdi, Azadeh Jafrasteh, Noushin Marhamati, Armin Shirvani, Abdollah Karimi, Sedigheh Rafiei Tabatabaei, Roxana Mansour Ghanaei, SeyedAlireza Fahimzad, Fariba Shirvani, Seyedeh Mahsan Hoseini-Alfatemi

“…Thus, this study aims to evaluate the epidemiological features, laboratory and imaging findings, and the type of treatments in children with novel coronavirus 2019 (COVID-19). Method. This study is conducted from March 2020–March 2021 by using the medical records of hospitalized confirmed COVID-19 children younger than 18 years in five cities of Iran: Tehran, Ahwaz, Isfahan, Bandar-Abbas, and Khorramabad. …”
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Noninvasive release of tendons using MRI guided focused ultrasound: a hybrid therapy using long-pulse focused ultrasound followed by thermal ablation by William Chu Kwan, Imogen den Otter-Moore, Ari Partanen, Karolina Piorkowska, Unni Narayanan, Adam C. Waspe, James M. Drake

“…We evaluated the safety profile of a novel hybrid protocol that minimizes thermal spread by combining long-pulse focused ultrasound followed by thermal ablation.Methods In-vivo Achilles tendons (hybrid N = 15, thermal ablation alone N = 21) from 15 to 20 kg Yorkshire pigs were randomly assigned to 6 treatment groups in two studies. …”
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Ideas of Multipolarity in the Conceptual Frame of the Soviet Diplomacy during the Final Phases of the Great Patriotic war (1943–1945) by I. E. Magadeev

“…Additionally, the essay introduces a novel dimension by surveying the viewpoints of other Soviet diplomats (S.A. …”
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Exosomes as Mediators of Cell-to-Cell Communication in Thyroid Disease by Yi Wang, Feng Xu, Jia-Yu Zhong, Xiao Lin, Su-Kang Shan, Bei Guo, Ming-Hui Zheng, Ling-Qing Yuan

“…Concentrated cargoes from parent cells are enveloped in exosomes, which are cell specific and may have functions in the recipient cell, reflecting a novel physiological and pathological mechanism in disease development. …”
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Engineering Magnetic Heterostructures with Synergistic Regulation of Charge‐Transfer and Spin‐Ordering for Enhanced Water Oxidation by Chongyan Hao, Yang Wu, Xiaobo Zheng, Yumeng Du, Yameng Fan, Weikong Pang, Anton Tadich, Shujun Zhang, Thomas Frauenheim, Tianyi Ma, Xiaoning Li, Zhenxiang Cheng

“…Abstract The design of heterojunctions offers a crucial solution for energy conversion and storage challenges, but current research predominantly focuses on charge transfer benefits, often neglecting spin attribute regulation despite the increasing recognition of spin‐sensitivity in many chemical reactions. In this study, a novel magnetic heterostructure, CoFe2O4@CoFeMo3O8, is designed to simultaneously modulate charge and spin characteristics, and systematically elucidated their synergistic impact on the oxygen evolution reaction (OER). …”
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Tissue-specific roles of de novo DNA methyltransferases by Dániel Márton Tóth, Flóra Szeri, Mária Ashaber, Muhyiddeen Muazu, Lóránt Székvölgyi, Tamás Arányi

“…DNMT3A and DNMT3B establish novel methylation patterns maintained by DNMT1 during replication. …”
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Deficient Purposeful Use of Forepaws in Female Mice Modelling Rett Syndrome by Bianca De Filippis, Mattia Musto, Luisa Altabella, Emilia Romano, Rossella Canese, Giovanni Laviola

“…Present results confirm behavioural and brain alterations previously reported in MeCP2-308 males and identify novel endpoints on which the efficacy of innovative therapeutic strategies for RTT may be tested.…”
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Q-learning global path planning for UAV navigation with pondered priorities by Kevin B. de Carvalho, Hiago de O.B. Batista, Leonardo A. Fagundes-Junior, Iure Rosa L. de Oliveira, Alexandre S. Brandão

“…This study introduces a novel approach to offline path planning in static environments, utilizing Q-learning as its foundation. …”
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Microwave-assisted synthesis and swelling behavior of poly lactic acid (PLA) grafted Cordia dichotoma gum-based hydrogels by Jyoti Sinha, Abubakar Hamisu Mijinyawa, Faisal Islam Chowdhury, Muhd Zu Azhan Yahya, Pramod Kumar Singh, Geeta Durga

“…The swelling of CDG-g-PLA in water was measured and found to be significantly lower than CDG, making them novel candidates for drug-delivery and sustainable food packaging applications.…”
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MacSyFinder v2: Improved modelling and search engine to identify molecular systems in genomes by Néron, Bertrand, Denise, Rémi, Coluzzi, Charles, Touchon, Marie, Rocha, Eduardo P.C., Abby, Sophie S.

“…We also introduce the novel macsydata companion tool that enables the easy installation and broad distribution of the models developed for MacSyFinder (macsy-models) from GitHub repositories. …”
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Experimental hypothermia by cold air: a randomized, double-blind, placebo-controlled crossover trial by Ane M. Helland, Sigurd Mydske, Jörg Assmus, Guttorm Brattebø, Øystein Wiggen, Haakon K. Kvidaland, Øyvind Thomassen

“…Shivering was effectively reduced, but not completely inhibited by the drug regimen, and core temperature declined at a rate of − 0.82 °C per hour. Conclusion The novel protocol utilizing cold air as a cooling method and drug-induced suppression of endogenous thermoregulation, is effective and enables future research projects. …”
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The Synergistic Effects of Celastrol in combination with Tamoxifen on Apoptosis and Autophagy in MCF-7 Cells by Lijun Wang, Luqun Tang, Chengyun Yao, Chunyan Liu, Yongqian Shu

“…Considering the urgent need for novel therapeutic strategies in anticancer therapy, this combinatorial approach is worthy of further investigation.…”
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A Weighted Bayesian Kernel Machine Regression Approach for Predicting the Growth of Indoor-Cultured Abalone by Seung-Won Seo, Gyumin Choi, Ho-Jin Jung, Mi-Jin Choi, Young-Dae Oh, Hyun-Seok Jang, Han-Kyu Lim, Seongil Jo

“…To address these challenges, we propose a novel probabilistic machine learning approach based on a Bayesian framework to predict abalone growth by modeling key environmental factors, including water temperature, pH, salinity, nutrient supply, and dissolved oxygen levels. …”
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High-Transmittance Subwavelength Metal Grating with Relief Structure Composed of Multiple Steps by Zhongfei Wang, Dawei Zhang, Qi Wang, Banglian Xu, Qingyong Tang, Yuanshen Huang, Songlin Zhuang

“…The optical performance of the novel structure is evaluated and compared in terms of the transmission efficiency and extinction ratio over the visible and near-infrared wavelength spectrum. …”
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