GFA-Net: Geometry-Focused Attention Network for Six Degrees of Freedom Object Pose Estimation by Shuai Lin, Junhui Yu, Peng Su, Weitao Xue, Yang Qin, Lina Fu, Jing Wen, Hong Huang

“…To overcome these limitations, we introduce the Geometry-Focused Attention Network (GFA-Net), a novel framework designed for more comprehensive feature extraction by analyzing critical geometric and textural object characteristics. …”
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C3AR1 as a target for preeclampsia: from bioinformatics and network pharmacology to experimental validation by Yongfeng Hu, Shaoqiang Li, Yunhui Hong, Dongxian Peng

“…It is crucial for cellular functions and inflammation, with future studies aiming to leverage this for novel preeclampsia treatments. Clinical trial Not applicable.…”
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Single-ion gel-polymer electrolyte for improving the performances of Li-ion batteries by Radu Dorin Andrei, Giorgian Cosmin Ungureanu, Luisa Roxana Mandoc, Soha Aldroubi, Nicolas Louvain, Julian Richard Tolchard, Mihaela Buga

“…In this work, we suggest a completely new strategy to deal with these issues: creating a Solid Molecular Ionic Composite Electrolyte (SMICE), an entirely novel type of gel-polymer electrolyte. This new membrane exhibits outstanding ionic conductivity at room temperature (3.3 mS·cm-1). …”
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Delving into biomarkers and predictive modeling for CVD mortality: a 20-year cohort study by Zhen Wu, Abdullahi Mohamud Hilowle, Ying Zhou, Changlin Zhao, Shuo Yang

“…The integration of cardiac biomarkers, lipid profiles, and inflammatory markers significantly improves the accuracy of predictive models for CVD-related mortality. This novel approach offers enhanced prognostication, with potential for further optimization through the inclusion of additional clinical and lifestyle data.…”
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Enhanced intestinal epithelial co-culture model with orbital mechanical stimulation: a proof-of-concept application in food nanotoxicology by Mattia Santoni, Giovanni Piccinini, Giovanni Piccinini, Giovanni Liguori, Maria Roberta Randi, Massimo Baroncini, Liliana Milani, Francesca Danesi

“…Here, we developed an enhanced Caco-2/HT29-MTX-E12 co-culture model incorporating orbital mechanical stimulation to better replicate intestinal conditions and investigate nanoparticle interactions.MethodsWe established co-cultures under static and dynamic conditions, evaluating their development through multiple approaches including barrier integrity measurements, gene expression analysis, and confocal microscopy. We introduced novel quantitative analysis of dome formation as a differentiation marker and demonstrated the model application by investigating cellular responses to titanium dioxide (TiO₂) nanoparticles in a digested food matrix.ResultsDynamic conditions accelerated epithelial differentiation, achieving functional barrier properties by day 14 rather than day 21, with enhanced mucin production and more organized three-dimensional structure. …”
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Natural Eutectic Solvent-Based Temperature-Controlled Liquid–Liquid Microextraction and Nano-Liquid Chromatography for the Analysis of Herbal Aqueous Samples by Álvaro Santana-Mayor, Giovanni D’Orazio, Miguel Ángel Rodríguez-Delgado, Bárbara Socas-Rodríguez

“…In this work, two novel (-)-menthol-based hydrophobic natural eutectic solvents with vanillin and cinnamic acid were prepared and applied as extraction solvents. …”
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If Music is Ongoing Experience, What Might Music Theory Be? . A Suggestion from the Drastic by Christopher F. Hasty

“…If we take experience as essentially predetermined by the musical work or, in cognitivist information processing terms, by rule-governed mechanisms for manipulating internal representations (be these rules syntactic or semantic) we shall not be able to account for the creativity of music and the production of novel meaning. The complexity or messiness of such production may seem an impediment to understanding music – it would seem to lead to the vagaries of the merely subjective, to mere appearance, or to a hopeless relativism that would in the end leave us speechless. …”
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An automated adaptive trading system for enhanced performance of emerging market portfolios by Cristiana Tudor, Robert Sova

“…We conclude that with the right investment tools, EMs continue to offer compelling opportunities that should not be overlooked. The novel AATS proposed in this study is such a tool, providing active EM investors with substantial value-added through its ability to generate abnormal returns, and can help to enhance the resilience of EMs by mitigating the cost of crises for those countries.…”
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Association between the triglyceride glucose body mass index and asthma: evidence from NHANES 2011–2018 by Sijia Yu, Shiping Wu, Shouxin Wei

“…The triglyceride-glucose body mass index (TyG-BMI) is a novel biomarker used to evaluate insulin resistance; however, limited research exists on the relationship between TyG-BMI and asthma. …”
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Use of Minimal Residual Disease Status to Reduce Uncertainty in Estimating Long-term Survival Outcomes for Newly Diagnosed Multiple Myeloma Patients by Naomi van Hest, Peter Morten, Keith Stubbs, Nicola Trevor

“…**Discussion:** Alternative methods to estimate long-term survival outcomes, such as a response-based PSM, can reduce uncertainty in modeling predictions around cost-effectiveness estimates for health technology assessment bodies and payers, thereby supporting faster market access for novel therapies with immature survival data. **Conclusions:** Use of MRD status in a response-based PSM reduces uncertainty in modeling long-term survival in patients with NDMM and provides a greater number of clinically plausible extrapolations compared with a standard PSM.…”
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Review—Recent Progress in Materials Development for Electrochemical Gas Sensors by Kening Lang, Tianyi Liu, Rishi J. Patel, Mark L. Ballentine, Alan J. Kennedy, Wu-Sheng Shih, Adam Scotch, Jiadeng Zhu

“…The unique properties of novel materials, including metal and metal oxides, carbon materials, conducting polymers, their composites, and others, are discussed in detail. …”
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Rare Cell Population Analysis in Early-Stage Breast Cancer Patients by Stefan Schreier, Prapaphan Budchart, Suparerk Borwornpinyo, Lakkana Adireklarpwong, Prakasit Chirappapha, Wannapong Triampo, Panuwat Lertsithichai

“…Design: We evaluated the validity of a multi-rare-cell detection platform and demonstrated the utility of a specific rare cell subset as a novel approach to characterize the breast cancer system. …”
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Coordinated charging of EV fleets in community parking lots to maximize benefits using a three-stage energy management system by Isha Chandra, Navneet Kumar Singh, Paulson Samuel, Mohit Bajaj, Ievgen Zaitsev

“…This paper presents a novel three-stage real-time Energy Management System (EMS) designed to coordinate EV charging in CPLs, integrating solar photovoltaics, wind energy, ESSs, and building backup units. …”
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In Vitro Effects of Strontium on Proliferation and Osteoinduction of Human Preadipocytes by V. Nardone, R. Zonefrati, C. Mavilia, C. Romagnoli, S. Ciuffi, S. Fabbri, G. Palmini, G. Galli, A. Tanini, M. L. Brandi

“…The aim of our study was to evaluate the in vitro effects of a wide range of strontium (Sr2+) concentrations on proliferation, ALP activity, and mineralization of a novel finite clonal hADSCs cell line, named PA20-h5. …”
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Expanding the clinical spectrum of 19p13.3 microduplication syndrome: a case report highlighting nephrotic syndrome and literature review by Wenjie Sun, Hong Yan, Mengxin Sun, Jie Wang, Kunxia Li

“…In this study, we report the case of a patient with 19p13.3 microduplication and novel clinical findings, specifically nephrotic syndrome. …”
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What behavior is important behavior? A systematic review of how wild and zoo-housed animals differ in their time-activity budgets by Robert Kelly, Marianne Freeman, Paul Rose, Paul Rose

“…Other species may adapt to captivity in novel ways, demonstrating flexibility in their behavior patterns without compromising welfare. …”
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Whole exome sequencing enables the correct diagnosis of Frank–Ter Haar syndrome in a Saudi family by Y. N. Khan, M. Imad A.M. Mahmud, N. Othman, H. M. Radzuan, S. Basit

“…Moreover, this study identified a novel homozygous missense variant (c.280C>G; p.R94G) in (NM_001308175.2) the SH3PXD2B gene as a causative variant for autosomal recessive FTHS. …”
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A detoxified TLR4 agonist inhibits tumour growth and lung metastasis of osteosarcoma by promoting CD8+ cytotoxic lymphocyte infiltration by Ryunosuke Oyama, Akira Nabeshima, Makoto Endo, Alexey Novikov, Toshifumi Fujiwara, Capucine Phelip, Nobuhiko Yokoyama, Yoshinao Oda, Martine Caroff, Yoshihiro Matsumoto, Jerome Kerzerho, Yasuharu Nakashima

“…Current immunotherapies show limited efficacy, highlighting the need for novel therapeutic approaches. Systemic immune activation by Toll-like receptor 4 (TLR4) immunostimulants has shown great promise; however, current TLR4 agonists’ toxicity hinders this systemic approach in patients with osteosarcoma. …”
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MEAT-SAM: More Efficient Automated Tongue Segmentation Model by Fudong Zhong, Chuanbo Qin, Yue Feng, Junying Zeng, Xudong Jia, Fuguang Zhong, Jun Luo, Min Yang

“…To tackle this challenge, this paper introduces a novel, more efficient automated tongue image segmentation model (MEAT-SAM). …”
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Blood from septic patients with necrotising soft tissue infection treated with hyperbaric oxygen reveal different gene expression patterns compared to standard treatment by Julie Vinkel, Alfonso Buil, Ole Hyldegaard

“…Conclusion The global gene expression pattern in blood changed in response to HBO2 treatment in a direction associated with clinical biochemistry improvement, and the study provides potential novel biomarkers and pathways for monitoring HBO2 treatment effects and predicting an HBO2 responsive NSTI-sepsis profile. …”
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