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6501
Identifying Complex Scheduling Patterns Among Patients With Cancer With Transportation and Housing Needs: Feasibility Pilot Study
Published 2025-01-01“…MethodsWe present a novel algorithm to calculate scheduling complexity from patient scheduling data. …”
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6502
Anti-allergic effect of 5,7-dihydroxy-4-methylcoumarin in IgE-mediated RBL-2H3 cells and PCA murine model
Published 2025-01-01“…Collectively, these results suggest that 5,7-dihydroxy-4-methylcoumarin holds promise as a novel candidate for the development of anti-allergic drugs.…”
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6503
Dental pulp stem cell-derived intracellular vesicles prevent orthodontic relapse by inhibiting PI3K/Akt/NF-κB-mediated osteoclast activity
Published 2025-01-01“…Conclusion This study highlights the potential of DPSC-IV as a novel preventive approach against orthodontic relapse, offering a novel strategy for maintaining long-term orthodontic stability. …”
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6504
Biomechanics in the tumor microenvironment: from biological functions to potential clinical applications
Published 2025-01-01“…This comprehensive review of biomechanics will enhance the understanding of the functional role of biomechanical forces and provide basic knowledge for the discovery of novel therapeutic targets.…”
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6505
Synovial Fluid Cell Proteomic Analysis Identifies Upregulation of Alpha-Taxilin Proteins in Rheumatoid Arthritis: A Potential Prognostic Marker
Published 2020-01-01“…Αlpha-Taxilin (α-Taxilin) has been found as one of the novel, significantly up regulated protein in RA. …”
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6506
The MIR181A2HG/miR‐5680/VCAN‐CD44 Axis Regulates Gastric Cancer Lymph Node Metastasis by Promoting M2 Macrophage Polarization
Published 2025-01-01“…MIR181A2HG‐based targeted therapy would represent a novel strategy for GC.…”
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6507
Cyclin-dependent protein kinases and cell cycle regulation in biology and disease
Published 2025-01-01“…Finally, we discuss how CDKs inhibitors have become standard therapies in selected human cancers and propose novel ways of investigation to export their targeting from cancer to other relevant chronic diseases. …”
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6508
Discovery and characterization of complete genomes of 38 head-tailed proviruses in four predominant phyla of archaea
Published 2025-01-01“…In this study, the complete genomes of 38 novel archaeal proviruses were identified for the following four dominant phyla: Halobacteriota, Thermoplasmatota, Thermoproteota, and Nanoarchaeota. …”
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6509
Nanopore Confinement Effect on the Phase Behavior of CO2/Hydrocarbons in Tight Oil Reservoirs considering Capillary Pressure, Fluid-Wall Interaction, and Molecule Adsorption
Published 2021-01-01“…The phase behavior for fluids in tight reservoirs is essential for a better understanding of the mechanics of fluid flow. A novel methodology is proposed to investigate the phase behavior of carbon dioxide (CO2)/hydrocarbons systems considering nanopore confinement. …”
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6510
Electroencephalography Biomarkers of α5-GABA Positive Allosteric Modulators in Rodents
Published 2025-03-01“…Background: Reduced cortical inhibition mediated by GABA (gamma-aminobutyric acid) is reported in depression, anxiety disorders, and aging. A novel positive allosteric modulator that specifically targets the α5-GABAA receptor subunit (α5-PAM), ligand GL-II-73 shows anxiolytic, antidepressant, and procognitive effects without the common side effects associated with nonspecific modulation by benzodiazepines such as diazepam, thus suggesting novel therapeutic potential. …”
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6511
Towards New Scaffolds for Antimicrobial Activity—In Silico/In Vitro Workflow Introducing New Lead Compounds
Published 2024-12-01“…<b>Conclusions</b>: The tested scaffolds could be considered as promising candidates for novel antimicrobials with improvements. Further experimentation is required to assess mechanisms of action and evaluate the efficacy and safety.…”
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6512
Efficient recovery of rare metal lanthanum from water by MOF-modified biochar: DFT calculation and dynamic adsorption
Published 2025-02-01“…Abstract In this research, a novel metal-organic framework-modified biochar composite (MIL-88b@BC) was created for the first time by modifying rice husk biochar using the excellent adsorption properties of metal-organic framework (MOF), as well as reducing the solubility of MOF using biochar as a substrate, aiming to improve the understanding of the adsorption characteristics of rare-earth metal recycling and to predict its adsorption mechanism. …”
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6513
Effects of Quetiapine on Novelty‐Related Object Recognition Memory and Hippocampal BDNF Level in Sleep‐Deprived Rats
Published 2025-01-01“…The present study aimed to evaluate the effects of treatment with QET on novel object recognition and hippocampal (hippo) brain‐derived neurotrophic factor (BDNF) levels in rats submitted to 72 h sleep deprivation (SD). …”
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6514
Dracula, le monstre et les savants : entre Darwin et Bunyan
Published 2009-03-01“…Among the novel’s characters, two are well identified scientists, Seward and Van Helsing; but a third also plays a major, though covert, role in it. …”
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6515
Parameters estimation of LFM signal based on Gaussian-weighted fractional Fourier transform
Published 2016-04-01“…To overcome the performance degradation of conventiona methods in low duty ratio condition, a novel me-thod of parameters estimation for LFM signal based on the Gaussian-weighted fractional Fourier transform (GFRFT) was proposed. …”
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6516
Performance evaluation and system design of 6G cooperative integrated sensing and communication technology
Published 2024-08-01“…The current status of CoISAC technology was summarized and analyzed. A novel performance metric and two cooperative approaches were proposed. …”
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6517
Rapid Diagnosis of Bacterial Infections Using Technologies Based on Nucleic Acid Detection
Published 1999-01-01“…This long delay often forces physicians to treat patients presumptively with broad-spectrum antibiotics. Novel diagnostic tests based on the detection of nucleic acids (DNA or RNA) offer a great potential for the rapid (approximately 1 h) diagnosis of bacterial infections. …”
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6518
Immobilization Technologies in Probiotic Food Production
Published 2013-01-01“…In the present review, the use of probiotic microorganisms for the production of novel foods is discussed, while the benefits and criteria of using probiotic cultures are analyzed. …”
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6519
Electrochemical Sensor for Determination of Parathion Based on Electropolymerization Poly(Safranine) Film Electrode
Published 2011-01-01“…Parathion has been determined with voltammetric technique based on a novel sensor fabricated by electropolymerization of safranine on a glassy carbon electrode (GCE). …”
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6520
Source-controlled OpenFlow data plane
Published 2015-03-01“…To resolve these issues, a novel model called the source-controlled Open-Flow(SCOF)was proposed. …”
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