Bioinformatics screening and clinical validation of CircRNA and related miRNA in male osteoporosis by Jiayi Li, Sijia Guo, Qingyun Sun, Ning An, Jisheng Lin, Qi Fei

“…It was ultimately found that three miRNAs were upregulated in MOP, while hsa-circ-9130, novel_circ_0014940 and hsa-circ-0054894 were upregulated, hsa-circ-2484 and novel_circ_0033084 were downregulated in patients with MOP. …”
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Detection of differences in physical symptoms between depressed and undepressed patients with breast cancer: a study using K-medoids clustering by Jianyao Tang, Bingqian Guo, Chuhan Zhong, Jing Chi, Jiaqi Fu, Jie Lai, Yujie Zhang, Zihan Guo, Shisi Deng, Yanni Wu

“…Pain-related symptom cluster and gastrointestinal symptom cluster were both identified in the depressed and undepressed patients. The novel immune system impairment symptom cluster consisting of bleeding and fever was found in the undepressed patients. …”
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Ion irradiation introduced high-density core-shell structured nanoprecipitates in FeCrNi by Yizhou Qian, Xiaolei Ma, Kangkang Wen, Siyu Chen, Yiheng Chen, Yugang Wang, Tongde Shen, Gang Sha, Chenxu Wang

“…This study explores the novel synthesis of high-density core-shell structured nanoprecipitates (NPs) within FeCrNi alloys via ion irradiation, aiming to enhance mechanical properties through NPs. …”
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LC-MS-Based Global Metabolic Profiles of Alternative Blood Specimens Collected by Microsampling by Marlene N. Thaitumu, Daniel Marques De Sá e Silva, Philippine Louail, Johannes Rainer, Glykeria Avgerinou, Anatoli Petridou, Vassilis Mougios, Georgios Theodoridis, Helen Gika

“…Their non-invasive way of use and the simplified logistics that they offer renders these technologies highly attractive in large-scale studies, especially the novel quantitative microsampling approaches such as VAMs or qDBS. …”
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Biomarker Investigation Using Multiple Brain Measures from MRI Through Explainable Artificial Intelligence in Alzheimer’s Disease Classification by Davide Coluzzi, Valentina Bordin, Massimo W. Rivolta, Igor Fortel, Liang Zhan, Alex Leow, Giuseppe Baselli

“…Specifically, we define a novel Explainable Artificial Intelligence (XAI) metric, based on gradient-weighted class activation mapping. …”
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Norepinephrine Infusion and the Central Venous Waveform in a Porcine Model of Endotoxemic Hypotension with Resuscitation: A Large Animal Study by Zachary R. Bergman, Roy K. Kiberenge, Richard W. Bianco, Gregory J. Beilman, Colleen M. Brophy, Kyle M. Hocking, Bret D. Alvis, Eric S. Wise

“…This allows contextualization of the novel, venous-derived signal f0 during vasopressor administration, a finding that must be understood prior to clinical translation.…”
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Synthesis of Closely‐Contacted Cu2O‐CoWO4 Nanosheet Composites for Cuproptosis Therapy to Tumors With Sonodynamic and Photothermal Assistance by Zhuoran Yang, Zhuo Li, Chunyu Yang, Li Meng, Wei Guo, Liqiang Jing

“…To fully realize its potential, the development of novel cuproptosis therapeutic agents and the achievement of efficient copper release are critical steps forward. …”
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Development and Videographic Evaluation of a Vascular Access Simulation-Based Curriculum for Surgical and Medical Trainees by Alaska Pendleton, MD, MPH, Tiffany R. Bellomo, MD, Srihari K. Lella, MD, Kristen Jogerst, MD, Ada Stefanescu, MD, MSc, Douglas Drachman, MD, Nikolaos Zacharias, MD, Anahita Dua, MD, MBA, MSc

“…The aim of this study was to develop and evaluate a novel 2-component simulation-based curriculum to address a lack of standardized access training and identify the most frequent errors in access. …”
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Incorporating low haemoglobin into a risk prediction model for conversion in minimally invasive gynaecologic oncology surgeries by Kevin H. Nguyen, Hyundeok Joo, Solmaz Manuel, Lee-may Chen, Lee-lynn Chen

“…The purpose of this study was to identify novel patient risk factors for conversion from minimally invasive to open surgeries for gynaecologic oncology operations.Methods This was a retrospective cohort study of 1356 patients ≥18 years of age who underwent surgeries for gynaecologic masses or malignancies between February 2015 and May 2020 at a single academic medical centre. …”
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The emerging role of blood-based biomarkers in early detection of colorectal cancer: A systematic review by Faris Shweikeh, Yuhao Zeng, Abdur Rahman Jabir, Erica Whittenberger, Saurav P. Kadatane, Yuting Huang, Mohamad Mouchli, Dani Ran Castillo

“…This review evaluates the promise of novel blood-based biomarkers for early detection of CRC. …”
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PAB-Mamba-YOLO: VSSM assists in YOLO for aggressive behavior detection among weaned piglets by Xue Xia, Ning Zhang, Zhibin Guan, Xin Chai, Shixin Ma, Xiujuan Chai, Tan Sun

“…Within the proposed model, a novel CSPVSS module, which integrated the Cross Stage Partial (CSP) structure with the Visual State Space Model (VSSM), has been developed. …”
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Enhanced mechanical properties of Al0.43CoCrFeNi2.1 high entropy alloy fabricated through complex shear flow casting: Experiment and MD simulation by Simeng Jiang, Yaya Zhao, Weijie Fan, Weiyang Xie, Yanlin Wang, Xiaohua Chen, Zidong Wang

“…In this study, a novel preparation method for high-entropy alloys (HEAs) was developed. …”
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Functional analysis of heterozygous variants in the SALL1 gene in 2 children with Townes-Brocks syndrome with FSGS by Rong Liang, Bixia Zheng, Chunli Wang, Sanlong Zhao, Wei Zhou, Ying Chen, Ruochen Che

“…Conclusions Two patients with Townes-Brocks syndrome (TBS) harboring novel variants presented atypical phenotypes, characterized primarily by significant and rapidly progressing renal involvement. …”
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Use of Immunostimulants in Shrimp Farming—A Bioeconomic Perspective by Héctor Rodrigo Nolasco-Alzaga, Elizabeth Monreal-Escalante, Mariel Gullian-Klanian, Juan Antonio de Anda-Montañez, Antonio Luna-González, Fernando Aranceta, Marcelo E. Araneda-Padilla, Carlos Angulo

“…An integrative bioeconomic model for testing a novel immunostimulant should contemplate technological, biological, and economic submodels at least; thus, financial variables, such as revenue, costs, and profitability, should also be considered for proper decision-making. …”
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The association of systemic immune-inflammation index with incident breast cancer and all-cause mortality: evidence from a large population-based study by Yu Li, Yu Li, Meng Yu, Ming Yang, Jingqi Yang

“…The Systemic Immune-Inflammation Index (SII), a novel marker derived from routine blood counts, has been suggested as a predictor of all-cause mortality and cardiovascular mortality. …”
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Exploring the impact of deleterious missense nonsynonymous single nucleotide polymorphisms in the DRD4 gene using computational approaches by Dipto Kumer Sarker, Pallobi Ray, Fayad Bin Abdus Salam, Shaikh Jamal Uddin

“…The aim of this study is to uncover novel damaging missense nsSNPs and their structural and functional effects on the DRD4 receptor. …”
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Dual Mechanisms of Action: Anti-Candida and Anti-Inflammatory Potential of <i>Lactobacillus</i> Fermentation Broth in Treating Vulvovaginal Candidiasis by Huann-Cheng Horng, Jin-Wei Xu, Yi-Shan Kuo, Yu-Sin Chen, Yu-Hsuan Chiu, Kuan-Hao Tsui, Yu-Tang Tung

“…This study investigated VAGINNE^®, a novel fermentation broth derived from <i>Lactobacillus</i> species, as a potential VVC treatment. …”
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A two-stage deep learning-based hybrid model for daily wind speed forecasting by Shahab S. Band, Rasoul Ameri, Sultan Noman Qasem, Saeid Mehdizadeh, Brij B. Gupta, Hao-Ting Pai, Danyal Shahmirzadi, Ely Salwana, Amir Mosavi

“…This study finds that the novel hybrid models exhibit superior performance to standalone GB and LSTM models, opening the pathway to alternative WS prediction techniques.…”
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Deep Learning in the Fast Lane: A Survey on Advanced Intrusion Detection Systems for Intelligent Vehicle Networks by Mohammed Almehdhar, Abdullatif Albaseer, Muhammad Asif Khan, Mohamed Abdallah, Hamid Menouar, Saif Al-Kuwari, Ala Al-Fuqaha

“…Specifically, we focus on the Controller Area Network (CAN) protocol, which is prevalent in in-vehicle communication systems, yet exhibits inherent security vulnerabilities. We propose a novel taxonomy categorizing IDS techniques into conventional ML, DL, and hybrid models, highlighting their applicability in detecting and mitigating various cyber threats, including spoofing, eavesdropping, and denial-of-service attacks. …”
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DFAST_QC: quality assessment and taxonomic identification tool for prokaryotic Genomes by Mohamed Elmanzalawi, Takatomo Fujisawa, Hiroshi Mori, Yasukazu Nakamura, Yasuhiro Tanizawa

“…This work aimed to address these challenges by introducing a novel tool that enhances taxonomic accuracy, offers a user-friendly interface, and supports large-scale analyses. …”
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