Extra-conventional strengthening mechanisms in non-recrystallized grains of an extruded Mg-Gd-Zr alloy by Qiang Yang, Shuhui Lv, Kai Guan, Zefeng Xie, Xin Qiu

“…This work supplements the strengthening mechanisms in traditional high-strength Mg-RE(-Zr) based alloys and provides novel insights in the development of ultra-high-strength Mg alloys.…”
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Human Immune System Increases Breast Cancer-Induced Osteoblastic Bone Growth in a Humanized Mouse Model without Affecting Normal Bone by Tiina E. Kähkönen, Mari I. Suominen, Jenni H. E. Mäki-Jouppila, Jussi M. Halleen, Azusa Tanaka, Michael Seiler, Jenni Bernoulli

“…Bone metastases are prevalent in many common cancers such as breast, prostate, and lung cancers, and novel therapies for treating bone metastases are needed. …”
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Unveiling the role of long non-coding RNAs in chicken immune response to highly pathogenic avian influenza H5N1 infection by Thi Hao Vu, Chaeeun Kim, Anh Duc Truong, Jun-Mo Kim, Hyun S. Lillehoj, Yeong Ho Hong

“…Through RNA sequencing, we identified novel lncRNAs and analyzed differentially expressed (DE) transcripts at 1 and 3 days post-infection (dpi) in chicken lung tissue. …”
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Comparative Assessment of Modulation Strategies in Modular Multilevel Converters: An Attempt for a Better Compromise Between the Efficiency and Capacitor Voltages' Dispersio... by Anthony Abdayem, Jean Sawma, Adrian Beneit, Ramon Blasco-Gimenez, Flavia Khatounian, Eric Monmasson

“…This article presents a novel sorting algorithm to address this challenge. …”
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Lutein-stevioside nanoparticle attenuates H2O2-induced oxidative damage in ARPE cells by Zhuqing Dai, Meimei Nie, Ye Chen, Jiangfeng Song, Yayuan Xu, Zhongyuan Zhang, Guodong Zhang, Shumo Yan, Xing Zhang, Dajing Li

“…In order to improve the bioavailability of lutein (LUT), a novel lutein-stevioside nanoparticle (LUT-STE) were prepared previously, but the information about LUT-STE on protecting of eye health was limited. …”
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Psoralidin: emerging biological activities of therapeutic benefits and its potential utility in cervical cancer by Tanya Tripathi, Apoorva Chaudhary, Divya Janjua, Udit Joshi, Nikita Aggarwal, Chetkar Chandra Keshavam, Alok Chandra Bharti

“…Owing to its high mortality rate, the identification of novel inhibitors preventing CaCx progression is of utmost importance. …”
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“When you’re in the office, it means you managed to get somewhere”: An interpretive descriptive study of the perceptions of adolescents accessing primary care for mental health ser... by Lisa De Panfilis, RN, MSc, Rebecca Ganann, RN, MSc, PhD, Gillian Mulvale, MA, PhD, Naomi Thulien NP-PHC, PhD, Ruta Valaitis, MA, PhD

“…Results: Adolescents perceived the process of accessing primary care for mental health services as complex and beginning prior to entering the primary care environment; a novel conceptual framework was developed to depict the process. …”
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Effect of a Short, Animated Storytelling Video on Transphobia Among US Parents: Randomized Controlled Trial by Doron Amsalem, Merlin Greuel, Shuyan Liu, Andrés Martin, Maya Adam

“…ObjectiveAddressing the urgent need for effective, scalable interventions, this study evaluates a novel digital approach: short, animated storytelling videos. …”
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Large-Area Clay Composite Membranes with Enhanced Permeability for Efficient Dye/Salt Separation by Yixuan Fu, Shuai Wang, Huiquan Liu, Ke Zhang, Lunxiang Zhang, Yongchen Song, Zheng Ling

“…However, the narrow layer spacing and tortuous interlayer transport channels of 2D-material-based membranes limit the processing capacity and the permeability of small salt ions for efficient dye/salt separation. In this work, a novel sepiolite/vermiculite membrane was fabricated using Meyer rod-coating and naturally occurring clay. …”
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Grazing by non‐native ungulates negatively impacts vegetation important to a native species of concern by Phillip A. Street, Levi Jaster, Thomas E. Dilts, Tessa L. Behnke, James S. Sedinger

“…Abstract Non‐native grazers compete with native species across the globe. We present a novel approach to study the composition of the herbaceous understory across three study areas within the Great‐Basin with different historic and contemporary grazing regimes. …”
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A multiplex microarray lateral flow immunoassay device for simultaneous determination of five mycotoxins in rice by Saowalak Adunphatcharaphon, Oluwatobi Kolawole, Thanasat Sooksimuang, Waraporn Panchan, Wannee Wasuthep, Anuwut Petdum, Grit Pichayawaytin, Rungroj Jintamethasawat, Narusorn Doljirapisit, Armote Somboonkaew, Prae Noppakuadrittidej, Sudtida Kaew-amdee, Manlika Makornwattana, Julie Meneely, Christopher T. Elliott, Awanwee Petchkongkaew, Nitsara Karoonuthaisiri

“…Principally, the microarray signals generated through a novel luminescent organic dye were captured to quantify mycotoxin levels in samples using a portable reader installed with a user-friendly interface. …”
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p97 Inhibitors Possessing Antiviral Activity Against SARS-CoV-2 and Low Cytotoxicity by Rui Ding, Tiffany C. Edwards, Prithwish Goswami, Daniel J. Wilson, Christine D. Dreis, Yihong Ye, Robert J. Geraghty, Liqiang Chen

“…<b>Methods:</b> We designed and synthesized novel p97 inhibitors based on the rearrangement of the central fused ring of our previously reported p97 inhibitors. …”
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Optimizing the production and efficacy of antimicrobial bioactive compounds from Streptomyces kanamyceticus in combating multi-drug-resistant pathogens by Zifang Shang, Vipasha Sharma, Liu Pai, Tarun Kumar, Sandip Patil, Sandip Patil

“…BackgroundThe rise of antibiotic-resistant pathogens has intensified the search for novel antimicrobial agents. This study aimed to isolate Streptomyces kanamyceticus from local soil samples and evaluate its antimicrobial properties, along with optimizing the production of bioactive compounds.MethodsSoil samples were collected from local regions, processed, and analysed for Streptomyces strains isolation using morphological characteristics and molecular identification through 16S rRNA gene PCR assay. …”
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A microbiota-derived metabolite, 3-phenyllactic acid, prolongs healthspan by enhancing mitochondrial function and stress resilience via SKN-1/ATFS-1 in C. elegans by Juewon Kim, Yunju Jo, Gyumin Lim, Yosep Ji, Jong-Hwa Roh, Wan-Gi Kim, Hyon-Seung Yi, Dong Wook Choi, Donghyun Cho, Dongryeol Ryu

“…Moreover, PLA-mediated longevity is associated with a novel age-related parameter, the Healthy Aging Index (HAI), introduced in this study, which comprises healthspan-related factors such as motility, oxygen consumption rate (OCR), and ATP levels. …”
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Leveraging hybrid model of ConvNextBase and LightGBM for early ASD detection via eye-gaze analysis by Ranjeet Bidwe, Sashikala Mishra, Simi Bajaj, Ketan Kotecha

“…This research introduces a novel method for eye gaze analysis to identify autistic traits in children. …”
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Effects of Immediate or Delayed Estradiol on Behavior in Old Menopausal Macaques on Obesogenic Diet by Kristine Coleman, Nicola D. Robertson, Adriane Maier, Cynthia L. Bethea

“…In addition, anxiety was assessed through the Human Intruder and Novel Object Tests. All animals gained weight, but ImE delayed the time to maximum weight achieved at 18 months. …”
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Genome-wide analysis in northern Chinese twins identifies twelve new susceptibility loci for pulmonary function by Tong Wang, Weijing Wang, Chunsheng Xu, Xiaocao Tian, Dongfeng Zhang

“…Conclusion Our GWAS results on Chinese dizygotic twins provide new references for the genetic regulation on pulmonary function. Twelve novel susceptibility loci are considered as possible crucial to pulmonary function.…”
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Hypericin mediated photodynamic therapy induces ferroptosis via inhibiting the AKT/mTORC1/GPX4 axis in cholangiocarcinoma by Wei An, Kai Zhang, Guangbing Li, Shunzhen Zheng, Yukun Cao, Jun Liu

“…This novel form of RCD has attracted great attention as a potential new target in clinical oncology during recent years. …”
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HBV Core Promoter Inhibition by Tubulin Polymerization Inhibitor (SRI-32007) by Raj Kalkeri, Junzhong Peng, Chunsheng Huang, Zhaohui Cai, Roger G. Ptak, Mark J. Suto

“…Our experiments illustrate the utility of repurposing strategy to identify novel antiviral chemical leads. HBV core promoter inhibitors such as SRI-32007 might enable the development of novel therapeutic strategies to combat HBV infections.…”
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Classifying early apple scab infections in multispectral imagery using convolutional neural networks by Alexander J. Bleasdale, J. Duncan Whyatt

“…This study fine-tunes CNN models to classify apple scab symptoms as they progress from the early to late stages of infection using a novel multispectral (RGB-NIR) time series created especially for this purpose.This novel multispectral dataset was used in conjunction with a large Apple Disease Identification (ADID) dataset created from publicly available, pre-existing disease datasets. …”
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