Restoration of Sestrin 3 Expression Mitigates Cardiac Oxidative Damage in Ischemia–Reperfusion Injury Model by Mina Park, Sunghye Cho, Dongtak Jeong

“…In conclusion, our findings suggest that targeting miR-25 may serve as a novel therapeutic modality to alleviate oxidative damage in the heart.…”
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ANKRD22 participates in the proinflammatory activities of macrophages in the colon cancer tumor microenvironment by Xiaoying Wang, Keqing Yang, Bin Yang, Rui Wang, Yongliang Zhu, Tianhui Pan

“…Reprogramming M2-type TAMs with immunosuppressive functions into M1-type TAMs with proinflammatory functions is a novel strategy for reshaping the tumor microenvironment (TME) and enhancing the efficacy of immunotherapy in colon cancer. …”
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Fungal Infections in Kidney Transplant Recipients: A Comprehensive Narrative Review by Maria Mazzitelli, Federico Nalesso, Alberto Enrico Maraolo, Vincenzo Scaglione, Lucrezia Furian, Annamaria Cattelan

“…Future research is needed to optimize diagnostic tools, identify novel antifungal agents, and develop better prophylactic strategies for high-risk transplant recipients.…”
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Discovery of Antimalarial Drugs from Streptomycetes Metabolites Using a Metabolomic Approach by Siti Junaidah Ahmad, Mohd Badrin Hanizam Abdul Rahim, Syarul Nataqain Baharum, Mohd Shukri Baba, Noraziah Mohamad Zin

“…Metabolomics approach in finding novel therapeutics agent for malaria offers dereplication step in screening phase to shorten the process. …”
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Probabilistic Short‐Term Solar Driver Forecasting With Neural Network Ensembles by Joshua D. Daniell, Piyush M. Mehta

“…We investigate the usage of principal component analysis (PCA) to enhance multivariate forecasting. A novel method, referred to as striped sampling, is created to produce statistically consistent machine learning data sets. …”
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Intra- and Extra-Articular Deformity of Lower Limb: Tibial Condylar Valgus Osteotomy (TCVO) and Distal Tibial Oblique Osteotomy (DTOO) for Reconstruction of Joint Congruency by Y. Watanabe, N. Takenaka, K. Kinugasa, T. Matsushita, T. Teramoto

“…Distal tibial oblique osteotomy (DTOO) is a novel surgery to improve the bony congruency of the ankle OA. …”
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Learning through “Research Cognitive Theory”: A new framework for developing 21st century research skills in secondary school students by Noora J. Al-Thani, Zubair Ahmad

“…This study introduces a novel framework for High School Research Cognitive Learning Program (HSRCLP), focused on developing 21st century research skills (including research behavior, scientific identity, and values for the scientific community) among high school students. …”
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The research progress of biologics in elderly-onset rheumatoid arthritis (EORA) by Yujie Li, Yifan Liu, Yanhui Tian, Huimin Gu, Qingliang Meng, Jiakang Cui, Junfu Ma

“…Future research should focus on validating the long-term safety of novel therapies and refining individualized treatment strategies to enhance patient outcomes and quality of life.…”
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Rainbow: An Operating System for Software-Hardware Multitasking on Dynamically Partially Reconfigurable FPGAs by Krzysztof Jozwik, Shinya Honda, Masato Edahiro, Hiroyuki Tomiyama, Hiroaki Takada

“…Finally, we present a novel model and implementation of a channel-based intertask communication and synchronization suitable for software-hardware multitasking with preemptable and clock-scalable hardware tasks. …”
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Genome-Wide Association Study towards Genomic Predictive Power for High Production and Quality of Milk in American Alpine Goats by Y. Tilahun, T. A. Gipson, T. Alexander, M. L. McCallum, P. R. Hoyt

“…The outcome of this study supports elucidation of novel genes that are important for livestock species in association to key phenotypic traits. …”
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Personalized Federated Learning for Heterogeneous Residential Load Forecasting by Xiaodong Qu, Chengcheng Guan, Gang Xie, Zhiyi Tian, Keshav Sood, Chaoli Sun, Lei Cui

“…Further, we introduce a novel differential privacy (DP) algorithm in the proposed system to provide an additional privacy guarantee. …”
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Design of a new class of broad-spectrum therapeutics targeted to drug-resistant bacteria by Amrutha Surendran, Agnes Turnbull, Allen Flockhart, Fern Findlay-Greene, Martyna Nowosielska, Donald Morrison, David J. Mincher, Samantha Donnellan

“…Key policy highlights Development of a novel class of antimicrobial compounds Drug screen against a WHO ‘high’ priority drug-resistant pathogen that poses the greatest threat to human health (methicillin-resistant Staphylococcus aureus) Drug screen against a surrogate for Mycobacterium tuberculosis, one of the leading causes of mortality worldwide.…”
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High SERS performance of functionalized carbon dots in the detection of dye contaminants by Yanqiu Yang, Lingru Kong, Yong Ding, Lixin Xia, Shuo Cao, Peng Song

“…The functional nanocomposite is novel and challenging to construct and implement through surface enhanced Raman scattering (SERS) strategy to reveal the contributions in application. …”
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Unusual Localization of Clostridium Difficile Infection in an Isolated Segment of the Descending Colon in a Critical Care Patient by Evgeni Brotfain, Leonid Koyfman, Amit Frenkel, Jochanan G. Peiser, Abraham Borer, Benjamin F. Gruenbaum, Alexander Zlotnik, Moti Klein

“…Here, we present a case of a 48-year-old man with Clostridium difficile colitis of an isolated segment in the descending colon treated by a novel catheter intraluminal antibiotic irrigation. …”
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Numerical Analysis of the Width Design of a Protective Pillar in High-Stress Roadway: A Case Study by FuZhou Qi, ZhanGuo Ma, Ning Li, Bin Li, Zhiliu Wang, WeiXia Ma

“…The width design of protective pillars is an important factor affecting the stability of high-stress roadways. In this study, a novel numerical modeling approach was developed to investigate the relationship between protective pillar width and roadway stability. …”
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Bioactive Compounds in Infant Formula and Their Effects on Infant Nutrition and Health: A Systematic Literature Review by Cristine Couto Almeida, Bianca Figueiredo Mendonça Pereira, Katia Christina Leandro, Marion Pereira Costa, Bernardete Ferraz Spisso, Carlos Adam Conte-Junior

“…Although the infant food industry has advanced in the last years, there is no consensus on whether novel bioactive ingredients added to infant formulas have the same functional effects as the compounds found in human milk. …”
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Evaluation for Retinal Therapy for RPE65 Variation Assessed in hiPSC Retinal Pigment Epithelial Cells by Benjamin M. Nash, To Ha Loi, Milan Fernando, Amin Sabri, James Robinson, Anson Cheng, Steven S. Eamegdool, Elizabeth Farnsworth, Bruce Bennetts, John R. Grigg, Seo-Kyung Chung, Anai Gonzalez-Cordero, Robyn V. Jamieson

“…Human induced pluripotent stem cells (hiPSCs) generated from patients and the derivative retinal cells enable the investigation of pathological and novel variants in relevant cell populations. Biallelic pathogenic variants in RPE65 cause early-onset severe retinal dystrophy (EOSRD) or Leber congenital amaurosis (LCA). …”
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Diagnosis of Intraductal Biliary Lesions: Towards Greater Accuracy and Safety by Sung Woo Ko, Seung Bae Yoon

“…In this study, we aimed to assess the efficacy and safety of a novel tapered-tip sheath system for tissue sampling from biliary strictures. …”
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Charge doping into spin minority states mediates doubling of T C in ferromagnetic CrGeTe3 by Liam Trzaska, Lei Qiao, Matthew D. Watson, Monica Ciomaga Hatnean, Igor Marković, Edgar Abarca Morales, Tommaso Antonelli, Cephise Cacho, Geetha Balakrishnan, Wei Ren, Silvia Picozzi, Phil D. C. King

“…Abstract The recent discovery of the persistence of long-range magnetic order when van der Waals magnets are thinned towards monolayers provides a tunable platform for engineering of novel magnetic structures and devices. Here, we study the evolution of the electronic structure of CrGeTe3 as a function of surface electron doping. …”
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Dorsal venous complex ligation‐free and parietal endopelvic fascia preserving in laparoscopic radical prostatectomy: A prospective study of single centre by Zhong‐Hua Yang, Yong‐Zhi Wang, Tao Liu, Hang Zheng, Xing‐Huan Wang

“…Abstract Objectives This study aims to describe a novel dorsal venous complex (DVC) ligation‐free and parietal endopelvic fascia preserving technique for laparoscopic radical prostatectomy and to evaluate its post‐operative outcomes. …”
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