Mitigation PFHxA-induced neurotoxicity in Carassius auratus brain cells by selenium-enriched Bacillus subtilis via the BDNF/PI3K/AKT/GSK-3β pathway by Yu-ting Lu, Zheng-yao Guo, Lei Guo, Yu-hua He, Li-ming Liu, Xue Jiao, Yue-hong Li

“…Additionally, our findings establish a novel theoretical framework for using selenium-enriched Bacillus subtilis in environmental toxicology. …”
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The Role of Pharmaceutical Innovation in Clinical Practice Guidelines for Chronic Diseases by Meaghan Roach, Natalie Land, Jennifer Hernandez, Reina Rau, Jacquelyn W. Chou, Stacey S. Hickson, Danielle F. Rollmann, J. Ross Maclean

“…The time from regulatory approval of novel pharmacotherapies to inclusion in guideline recommendations varied considerably by disease area and geography. …”
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The Quality of Veterans Healthcare Administration Cardiovascular Care by D. Elizabeth Le, MD, Bhaskar L. Arora, MBBS, Faith R. Kelly, MD, Stephen W. Waldo, MD, Merritt Raitt, MD, Paul Heidenreich, MD, MS, Samit M. Shah, MD, PhD, Ali E. Denktas, MD, Kreton O. Mavromatis, MD

“…This paper reviews the quality of cardiovascular care delivered by the VHA in comparison to community care, which is care delivered in non-VHA facilities by non-VHA providers and is authorized and paid for by VHA, examining quality metrics and highlighting novel national care programs. The critical examination of this data is valuable for deriving health care policy, sharing novel and effective quality initiatives throughout the healthcare sector, and will help veterans and their providers make important healthcare decisions.…”
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Development of a Deep Learning‐Assisted Mobile Application for the Identification of Nematodes Through Microscopic Images by Naseeb Singh, Ashish Kumar Singh, L. K. Dhruw, Simardeep Kaur, S. Hazarika, K. K. Mishra, V. K. Mishra, Laxmi Kant

“…A novel lightweight convolutional neural network (CNN) was developed to identify the nematodes belonging to different trophic groups (Heterorhabditis indica, Meloidogyne incognita, Helicotylenchus, Anguina tritici, and Xiphinema). …”
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A handheld milk conductivity sensing device (Mylee) for measuring secretory activation progress in lactating women: a device validation study by Sharon Haramati, Anastasia Firsow, Daniela Abigail Navarro, Ravid Shechter

“…Here we evaluate the validity of a novel milk-sensing device (Mylee) for measuring the progress of milk maturation and secretory activation status. …”
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Shared genetic factors and the interactions with fresh fruit intake contributes to four types squamous cell carcinomas. by Mengqing Mo, Can Hou, Huangbo Yuan, Renjia Zhao, Mingyang Chen, Yanfeng Jiang, Kelin Xu, Tiejun Zhang, Xingdong Chen, Chen Suo

“…Credible risk variants (CRVs) were combined risk SNPs reported in GWAS Catalog and our study, followed by comprehensive bioinformatics analyses. We identified six novel index SNPs in the progression of SCCs, which were also strongly interacted with fresh fruit intake. …”
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Responses to novelty in wild insular birds: comparing breeding populations in ecologically contrasting habitats by Samara Danel, Nancy Rebout, Léna Bureau, Timothée Zidat, Dora Biro, Francesco Bonadonna

“…In this study, we presented novel objects to two geographically isolated breeding populations of the black-faced sheathbill (Chionis minor), a sedentary land-based bird that frequents remote sub-Antarctic islands. …”
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Circular RNA microarray expression profile and potential function of circDOCK1 in colorectal cancer by Guojing Zhang, Xiaoyan Wu, Hongmin Fu, Daqing Sun

“…Therefore, there exists a critical need to identify novel markers facilitating early CRC detection and prognosis. …”
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A deep learning method for differentiating safflower germplasm using optimal leaf structure features by Hoang Thien Van, Phuong Thuy Khuat, Trang Van, Thai Thanh Tuan, Yong Suk Chung

“…To address this, we introduce a novel comprehensive leaf database of safflower varieties that is meticulously curated by experts. …”
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Metallothionein II treatment mitigates rotenone-induced neurodegeneration in zebrafish models of Parkinson’s disease by Yong Hui Nies, Wei Ling Lim, Norwahidah Abd Karim, Mohamad Fairuz Yahaya, Seong Lin Teoh

“…Current therapies offer symptomatic relief but fail to halt disease progression, highlighting the need for novel therapeutic strategies. This study explores the neuroprotective potential of exogenous human metallothionein 2 (hMT2) peptide in a rotenone-induced PD zebrafish model.MethodsAdult zebrafish were divided into four groups: control, rotenone-treated, hMT2 pre-treatment, and hMT2 co-treatment. …”
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Energy feature extraction and visualization of voltage sags using wavelet packet analysis for enhanced power quality monitoring by M. S. Priyadarshini, Mohit Bajaj, Ievgen Zaitsev

“…This paper introduces a novel approach to voltage sag analysis by employing wavelet packet analysis combined with energy-based feature extraction to enhance PQ monitoring. …”
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An Integrated Consensus Improving Strategy Based on PL-Wasserstein Distance and Its Application in the Evaluation of Network Public Opinion Emergencies by Shitao Zhang, Zhenzhen Ma, Xiaodi Liu, Zhiying Wang, Lihui Jiang

“…To address such problems, this paper presents a novel adaptive consensus reaching model for multiattribute group decision making (MAGDM) with probabilistic linguistic decision matrices (PLDMs). …”
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Association of functional variants in miRNA genes with the risk of coronary heart disease by Taqweem Ul Haq, Muhammad Riaz Khan, Sajjad Ali, Tariq Aziz, Thamer H. Albekairi, Aftab Ali Shah

“…Conclusion Our findings suggest that functional variants rs2858060, rs6505162, and a novel triplet insertion (CAC) in MIR222, MIR423, and MIR4274 respectively are strongly associated with CHD. …”
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Evaluating researches on urban housing indicators in current decade based on PRISMA method by Mohammadreza Zamiri, Mahin Nastaran, Mahmud Galenoyi

“…The results have shown that applying quantitative methods on urban indicators led to analogous assessments in various contexts and using novel methods and models, especially applying qualitative and mixed methods would resulted in novel and efficient perspectives to future urban housing programming and applying the PRISMA method would increase quality of survey reviews and strongly recommend to achieve comprehensive and qualified study of similar researches.…”
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A review of smart structures and adaptation of 3d printing methods for future fashion applications by Viktorija Diak

“…However, the creation of such novel materials/structures and their integration with traditional fibres present numerous challenges, urging the industry to explore new manufacturing methods. …”
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Genetic Algorithm Integrated Fuzzy AHP-VIKOR Approach for the Investigation of W-Cut Insert Heat Exchanger for Cooling of Dielectric Fluid Used in Ultra-High Voltage Transformer by N. Vasantha Gowri, J. Samson Isaac, T. Muralikrishna, G. Suresh Babu, Melvin Victor Depoures, S. Sekar, P. Sasirekha, M. Ramesh, S. Prabhakar

“…This study proposes a novel W-cut twisted tape to evaluate and enhance the effectiveness of novel grooved tube heat exchanger. …”
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Evaluation of Network Security Service Provider Using 2-Tuple Linguistic Complex q-Rung Orthopair Fuzzy COPRAS Method by Sumera Naz, Muhammad Akram, Mohammed M. Ali Al-Shamiri, Muhammad Ramzan Saeed

“…This research introduces a novel decision-making method utilizing the 2-tuple linguistic complex q-rung orthopair fuzzy numbers (2TLCq-ROFNs) to tackle this issue. …”
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Free-space optical spiking neural network. by Reyhane Ahmadi, Amirreza Ahmadnejad, Somayyeh Koohi

“…In this work, we introduce the pioneering Free-space Optical Deep Spiking Convolutional Neural Network (OSCNN), a novel approach inspired by the computational model of the human eye. …”
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New perspectives on the glymphatic system and the relationship between glymphatic system and neurodegenerative diseases by Yan-rui Sun, Qian-Kun Lv, Jun-Yi Liu, Fen Wang, Chun-Feng Liu

“…This emerging waste clearance mechanism offers a novel perspective on the removal of pathological substances in ND. …”
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Biological Evaluation of Platinum(II) Sulfonamido Complexes: Synthesis, Characterization, Cytotoxicity, and Biological Imaging by Charini Maladeniya, Taniya Darshani, Sameera R. Samarakoon, Frank R. Fronczek, W. M. C. Sameera, Inoka C. Perera, Theshini Perera

“…Platinum-based compounds are actively used in clinical trials as anticancer agents. In this study, two novel platinum complexes, (C1 = [PtCl2(N(SO2quin)dpa)], C2 = [PtCl2(N(SO2azobenz)dpa)]) containing quinoline and azobenzene appended dipicolylamine sulfonamide ligands were synthesized in good yield. …”
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