Reduction of chickens use to perform in vitro pre-screening of novel anticoccidials by miniaturisation and increased throughput of the current Eimeria tenella compound-screening model [version 2; peer review: 2 approved, 1 not approved] by Virginia Marugan-Hernandez, Javier Regidor-Cerrillo, Luis Ortega-Mora, Sara Arias-Maroto, Kelsilandia Aguiar-Martins

“…We have developed an in vitro model for the evaluation of potential anticoccidial properties of novel compounds aimed to control chicken coccidiosis, a costly disease for the poultry industry. …”
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MFBTFF-Net: A Novel Multi-Frequency Brightness Temperature Feature Fusion Network for Global Lunar Surface Oxides Abundance Estimation With Chang'e-2 Lunar Microwave Sounder Data by Yu Li, Zifeng Yuan, Sarah Mazhar, Zhiguo Meng, Yuanzhi Zhang, Jinsong Ping, Ferdinando Nunziata

“…In this article, we propose a novel deep learning model named multifrequency brightness temperature feature fusion network (MFBTFF-Net) for processing Chang'e-2 lunar microwave sounder (CELMS) data and it exploits the thermal radiation features related to various drilling depths to acquire the global lunar oxide abundance maps. …”
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Enhancing corrosion resistance of Mg-Al-Mn-Ca-Y dilute alloy via novel core-shell structured Al8Mn4Y-Al2Ca and controllable solute segregation by Xiaorui Dong, Min Zha, Dawei Wang, Siqing Wang, Yajie Yang, Hailong Jia

“…A novel core-shell structured Al8Mn4Y-Al2Ca phase and controllable solute-segregation are elaborately designed in dilute Mg-0.6Al-0.5Mn-0.1Ca-0.1Y alloy (wt.%), via incomplete peritectic transformation during twin-roll casting. …”
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Characterization and Probiotic Potential of <i>Levilactobacillus brevis</i> DPL5: A Novel Strain Isolated from Human Breast Milk with Antimicrobial Properties Against Biofilm-Forming <i>Staphylococcus aureus</i> by Ivan Iliev, Galina Yahubyan, Elena Apostolova-Kuzova, Mariyana Gozmanova, Daniela Mollova, Iliya Iliev, Lena Ilieva, Mariana Marhova, Velizar Gochev, Vesselin Baev

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Genetic Algorithms in Antennas and Smart Antennas Design Overview: Two Novel Antenna Systems for Triband GNSS Applications and a Circular Switched Parasitic Array for WiMax Applications Developments with the Use of Genetic Algorithms by Stylianos C. Panagiotou, Stelios C. A. Thomopoulos, Christos N. Capsalis

“…Two novel antenna systems are presented to cover the new GPS/Galileo band, namely, L5 (1176 MHz), together with the L1 GPS/Galileo and L2 GPS bands (1575 and 1227 MHz). …”
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Molecular docking and dynamics studies to identify novel active compounds targeting potential breast cancer receptor proteins from an indigenous herb Euphorbia thymifolia Linn [version 3; peer review: 2 approved] by ShamaPrasada K, Reshma Kumarchandra, Vasavi Kumblekar, K Sreedhara Ranganath Pai, Suman Manandhar, Sharada Rai, Rajeshwari Shastry

“…This increased burden demands new targeted therapies with novel compounds either synthetically produced or derived from indigenous plants, which could be a promising approach for the development of drugs. …”
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A novel treatment strategy with hyperbaric oxygen of chronic osteomyelitis and pseudoarthrosis in a child with congenital hereditary sensory and autonomic neuropathy type 4 congenital insensitivity to pain with anhidrosis syndrome: a case report by Anders Kjellberg, Rebecca Gustafsson, Pavel Antonsson, Henrik Hedelin

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Genomic insights into the alphaproteobacterium Georhizobium sp. MAB10 revealed a pathway of Mn(II) oxidation-coupled anoxygenic photoautotrophy: a novel understanding of the biotic process in deep-sea ferromanganese nodule formation by Xiuli Xu, Litao Zhang, Fuhang Song, Guoliang Zhang, Linlin Ma, Na Yang

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CLN-978, a novel half-life extended CD19/CD3/HSA-specific T cell-engaging antibody construct with potent activity against B-cell malignancies with low CD19 expression by Agapitos Patakas, Bochong Li, Naveen K Mehta, Kristan Meetze, Patrick A Baeuerle, Jennifer S Michaelson, Hannah M Findlay, Timothy B London

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Assessment of a novel unidirectional mid-term absorbable barbed suture versus a competitor barbed suture for vaginal cuff closure after gynaecology surgery, study protocol of a randomized controlled trial - BARHYSTER by Petra Baumann, Lourdes Hinojosa Sánchez, Núria Grané Garcia, Larisa Sologiuc, Amadeus Hornemann

“…The current study investigates the clinical outcome of a novel unidirectional mid-term absorbable barbed suture which differs in its configuration from other barbed sutures. …”
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Design, Synthesis, Antibacterial and Antifungal Activity of Novel 2-[(E)-2-aryl-1-ethenyl]-3-(2-sulfanyl-1H-benzo[d]imidazole-5-yl)-3,4- dihydro-4-quinolinones by Anisetti Ravinder Nath, Malladi Srinivas Reddy

“…The novel 2-[(E)-2-aryl-1-ethenyl]-3-(2-sulfanyl-1H-benzo[d]imidazole-5-yl)-3,4- dihydro-4-quinolinones (4a-j) analogs were synthesized by Knoevenagel condensation of a solution of 2-methyl-3-(2-sulfanyl-1H-benzo[d]imidazole-5-yl)-3,4-dihydro-4-quinazolinone (3) with aromatic aldehyde in presence of catalytic amount of piperidine. …”
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HAYALÎ BİR COĞRAFYA TASAVVURU: ORTA ASYA (1908-1923) -II. MEŞRUTİYET DÖNEMİ HİKÂYE VE ROMANI- / AN IMAGINARY ENVISAGEMENT OF GEOGRAPHY: CENTRAL ASIA (1908-1923) NARRATIVES AND NOVELS OF THE PERIOD OF II. CONSTITUTIONAL MONARCHY by Betül COŞKUN

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CO₂/CH₄ and CO₂/CO Selective Pebax-1657 Based Composite Hollow Fiber Membranes Prepared by a Novel Dip-Coating Technique by Dionysios S. Karousos, George V. Theodorakopoulos, Francesco Chiesa, Stéphan Barbe, Mirtat Bouroushian, Evangelos P. Favvas

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A NMR-Based Metabolomic Approach to Investigate the Antitumor Effects of the Novel [Pt(η1-C2H4OMe)(DMSO)(phen)]+ (phen = 1,10-Phenanthroline) Compound on Neuroblastoma Cancer Cells by Federica De Castro, Erika Stefàno, Erik De Luca, Antonella Muscella, Santo Marsigliante, Michele Benedetti, Francesco Paolo Fanizzi

“…NMR-based metabolomics is a very effective tool to assess the tumor response to drugs by providing insights for their mode of action. Recently, a novel Pt(II) complex, [Pt(ƞ1-C2H4OMe)(DMSO)(phen)]+ (phen =  1,10-phenanthroline), Pt-EtOMeSOphen, was synthesized and studied for its antitumor activity against eight human cancer cell lines. …”
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Ranakinestatin-PPF from the Skin Secretion of the Fukien Gold-Striped Pond Frog, Pelophylax plancyi fukienensis: A Prototype of a Novel Class of Bradykinin B2 Receptor Antagonist Peptide from Ranid Frogs by Jie Ma, Yu Luo, Lilin Ge, Lei Wang, Mei Zhou, Yingqi Zhang, Jinao Duan, Tianbao Chen, Chris Shaw

“…Here, we describe the identification, structural and functional characterization of a heptadecapeptide (DYTIRTRLHQGLSRKIV), named ranakinestatin-PPF, from the skin of the Chinese ranid frog, Pelophylax plancyi fukienensis, representing a prototype of a novel class of bradykinin B2-receptor specific antagonist. …”
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A novel hybrid system consisting of direct ammonia solid oxide fuel cell, gas turbine and dual-loop organic rankine cycle (DA-SOFC-GT-ORC): Multi-objective optimization and performance analysis by Weihua Cai, Hao Zhang, Xunjian Che, Zhongnong Zhang, Qian Li, Benan Cai, Kexin Liu

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A novel “lateral approach short axis in-plane” technique vs. conventional “short-axis out-of-plane approach” for ultrasound-guided internal jugular vein access: a prospective randomized non-inferiority trial by Michal Kalina, Patricia Vargová, Adéla Bubeníková, Roman Škulec, Vladimír Černý, David Astapenko

“…Therefore, this non-inferiority trial aimed to describe the novel approach and compare the novel lateral in-plane short-axis approach for IJV access with the conventional short-axis out-of-plane approach. …”
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Secukinumab-Induced Inflammatory Bowel Disease in a Patient Treated for Chronic Plaque Psoriasis and Psoriatic Arthritis: A Case Report and Review of the Role of Novel Biologic Agents Targeting the p19 Subunit of IL-23 by K. M. Darch, T. L. Holland, L. J. Spelman

“…The availability of a range of novel, targeted therapies for their treatment, most notably the availability of biologic agents, has revolutionised management of these conditions and allowed for significant improvements in patient outcomes. …”
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Medical (Mal)Practice and the Illusion of Progress in Edward Berdoe’s St Bernard’s: The Romance of a Medical Student and Leonard Graham’s The Professor’s Wife: A Genealogical Analysis of Epistemological and Ethical Arguments in Two Late-Victorian Novels by Adrian Tait

“…As these novels suggest, ethical issues were discounted by scientized medical professionals now intent on pursuing their research, often without care for the cost in suffering.…”
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Clean Procedure and DFT Study for the Synthesis of 2-Amino-3-ethoxycarbonyl-4-(aryl)-4H-pyrano-[3,2-c]-chromene-5-ones Derivatives: A Novel Class of Potential Antimicrobial and Antioxidant Agents by R. Medyouni, N. Hamdi, R. Ben Said, A. S. Al-Ayed, Fethi Zagrouba

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