Survival outcomes of surgery and adjuvant chemotherapy in early-stage small cell and large cell lung cancer: a novel focus on tumors less than 1 cm by Jorge Raul Vazquez-Urrutia, Junjia Zhu, Shinkichi Takamori, Max Greenberg, Priyanka Bhatia, Takefumi Komiya

“…This study assesses the survival benefits of adjuvant chemotherapy after surgical resection with a novel focus on tumors less than 1 cm. Materials and methods Data from the National Cancer Database (NCDB) was extracted for patients with SCLC (n = 11,962) and LCNEC (n = 6821) who underwent surgical resection between 2004 and 2020. …”
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On the Use of Molecular Weight Cutoff Cassettes to Measure Dynamic Relaxivity of Novel Gadolinium Contrast Agents: Example Using Hyaluronic Acid Polymer Complexes in Phosphate-Buffered Saline by Nima Kasraie, Henry Wayne Oviatt, Geoffrey David Clarke

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Developing a novel model for predicting overall survival in late-onset colon adenocarcinoma patients based on LODDS: a study based on the SEER database and external validation by Chen Chen, Heng-Bo Xia, Wei-Wei Yuan, Meng-Ci Zhou, Xue Zhang, A.-Man Xu

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Oxyresveratrol as a novel ferroptosis inducer exhibits anticancer activity against breast cancer via the EGFR/PI3K/AKT/GPX4 signalling axis by Lei Xiang, Qingzhou Li, Zhiwei Guan, Guilin Wang, Xiankuo Yu, Xianwen Zhang, Guochen Zhang, Jushan Hu, Xue Yang, Mingrui Li, Xilinqiqige Bao, Yumei Wang, Dong Wang

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A novel method to determine background concentrations and spatial distributions of heavy metals in soil at large scale using machine learning coupled with remote sensing-terrain attributes by Magboul M. Sulieman, Fuat Kaya, Abdullah S. Al-Farraj, Eric C. Brevik

“…Thus, preventing pollution and protecting pristine soils and preindustrial areas from human activities that lead to the concentration of heavy metals (HMs) is a priority. Here, a novel methodology was proposed to establish background concentrations of eight soil HMs, cobalt (Co), chromium (Cr), copper (Cu), iron (Fe), manganese (Mn), nickel (Ni), lead (Pb), and zinc (Zn), and digitally map their spatial distributions in an area (i.e., harrats region) that has not yet been impacted by industrial activity. …”
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Critical Care Management for Novel 2019 SARS-CoV-2 and HCoV-NL63 Coinfection in a Young Immunocompromised Patient: A Chicago Experience by Alejandro Sanchez-Nadales, Miguel Treminio-Quezada, Hasan Abad, Jessica Navarro-Motta, Pamela Contreras-Chavez, Anil Kachru, Chae Chu

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Case report: Atopic dermatitis-like skin manifestations in hypohidrotic ectodermal dysplasia caused by a novel splice site mutation of the EDA gene successfully treated with dupilumab by Eri Uchiyama, Kiminobu Takeda, Hiroto Ono, Akira Shimizu, Sumihito Togi, Hiroki Ura, Yo Niida

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Free vibration analysis of the structural integrity on the porous functionally graded plates using a novel Quasi-3D hyperbolic high order shear deformation theory by Mohammed Hadj Meliani, Mohammed Amine Kenanda, Fodil Hammadi, Zakaria Belabed

“… In this study, a novel quasi-three dimensional hyperbolic high-order shear deformation theory (quasi-3D HHSDT) is developed for free vibration analysis of porous functionally graded plates (FGPs). …”
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Isolation of a Novel Caprine <i>Eimeria christenseni</i> Strain (GC) in Canary Islands and Analysis of Parasitological, Clinical, and Pathological Findings on Experimentally Infected Goat Kids by Emilio Barba, José Manuel Molina, Francisco Rodríguez, Otilia Ferrer, María Carmen Muñoz, Liliana M. R. Silva, María Cristina Del Río, José Adrián Molina, Anja Taubert, Carlos Hermosilla, Antonio Ruiz

“…The results showed that the Gran Canaria (GC) <i>E. christenseni</i> strain had similar morphological and biological characteristics to those previously described, but no significant clinical signs were observed despite the high oocyst counts here recorded. The novel strain isolated would therefore be of low pathogenicity but still able to develop significant immunoprotective responses upon challenge infections. …”
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Novel analytical superposed nonlinear wave structures for the eighth-order (3+1)-dimensional Kac-Wakimoto equation using improved modified extended tanh function method by Wafaa B. Rabie, Hamdy M. Ahmed, Taher A. Nofal, E. M. Mohamed

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Mebendazole Exerts Anticancer Activity in Ovarian Cancer Cell Lines via Novel Girdin-Mediated AKT/IKKα/β/NF-κB Signaling Axis by Rahul Gupta, Dipanjan Roy, Arijit Ghosh, Yasmin Begum, Dipanjan Ghosh, Snehasikta Swarnakar

“…Mechanistic studies revealed a significant downregulation of Girdin, an Akt modulator, along with reduced p-Akt, p-IKKα/β, and p-NF-κB, indicating MBZ’s novel mechanism of action through the Girdin-mediated Akt/IKKα/β/NF-κB signaling axis. …”
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A Novel Liquid Chromatography–Tandem Mass Spectrometry Method to Quantify Tryptophan and Its Major Metabolites in Serum to Support Biomarker Studies in Patients with Cancer Undergoing Immunotherapy by Anna Siemiątkowska, Barbara Kuźnar-Kamińska, Katarzyna Kosicka-Noworzyń, Kamila Nowaczewska, Hanna Winiarska, Dominika Popiołek, Filip Kamiński, Franciszek K. Główka

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Novel Convolutional Restricted Boltzmann Machine manifold learning inspired dynamic user clustering hybrid precoding for millimeter-wave massive multiple-input multiple-output systems by Xiaoping Zhou, Haichao Liu, Bin Wang, Qian Zhang, Yang Wang

“…We model each user set as a novel Convolutional Restricted Boltzmann Machine manifold, and the problem is transformed into cluster-oriented multi-manifold learning. …”
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Efficient adsorption of ofloxacin in a novel nanocomposite formed by nano-hexagonal boron nitride fused with zeolite imidazolite skeleton-8: Experimental and molecular dynamics simulation studies by Zefang Huang, Yuankai Hong, Yiqun Cui, Huiying Guo, Yan Long, Jinshao Ye

“…This study synthesized three novel nanocomposite materials, ZIF-8@h-BN-X, using an in-situ growth method by adjusting h-BN content. …”
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A Novel Signal-Amplified Immunoassay for the Detection of C-Reactive Protein Using HRP-Doped Magnetic Nanoparticles as Labels with the Electrochemical Quartz Crystal Microbalance as a Detector by Ning Gan, Ping Xiong, Ji Wang, Tianhua Li, Futao Hu, Yuting Cao, Lei Zheng

“…A novel horseradish peroxidase- (HPR-) doped magnetic core-shell Fe3O4@SiO2@Au nanocomposites (Fe-Au MNPs) were employed on immunoassay for the determination of C-reactive protein (CRP) based on a electrochemical quartz crystal microbalance detector (EQCM). …”
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Detailed biogeographical mapping as a useful novel tool for the conservation of endemic taxa: a case of study for Iberian orchids [version 2; peer review: 2 approved] by Angel Penas, Alejandro González-Pérez, Raquel Alonso-Redondo, Norma Yolanda Ochoa-Ramos, Aitor Álvarez-Santacoloma, Sara del Río, Giovanni-Breogán Ferreiro-Lera

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A Novel Gridless Non-Uniform Linear Array Direction of Arrival Estimation Approach Based on the Improved Alternating Descent Conditional Gradient Algorithm for Automotive Radar System by Mingxiao Shao, Yizhe Fan, Yan Zhang, Zhe Zhang, Jie Zhao, Bingchen Zhang

“…In this paper, we propose a novel algorithm for DOA estimation in NULA, drawing inspiration from the alternating descent conditional gradient algorithm framework. …”
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AgIO4 nanoparticles decorated on SrTiO3 microspheres as a novel Z-scheme composite photocatalyst for efficient solar-driven degradation of cefixime by Lim Khar-Lok, Sin Jin-Chung, Zeng Honghu

“…This study introduced a novel Z-scheme SrTiO3/AgIO4 composite synthesized via a solvothermal-sonochemical route, which aimed to enhance the photocatalytic degradation of cefixime under simulated sunlight. …”
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Efficacy and Safety of a Novel Low-Dose Water-Dispersible Turmeric Extract in the Management of Knee Osteoarthritis: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial by Thanawala S, Shah R, Alluri KV, Bhupathiraju K, Prasad N, Agarwal Y

“…This study evaluated the efficacy and safety of a novel low-dose water-dispersible turmeric extract containing 60% natural curcuminoids (WDTE60N) in participants with mild-to-moderate knee osteoarthritis.Patients and Methods: This double-blind, randomized, placebo-controlled trial was conducted at two orthopedic centers in Uttar Pradesh, India (July 2023–November 2023). …”
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Significantly Delayed Development of Polyarthritis with Active Tenosynovitis after Possible Temporary Neutropenic Immune-Related Adverse Events Caused by Atezolizumab Treatment: A Novel Case Report by Yoshitaka Saito, Yoh Takekuma, Hajime Asahina, Ryo Hisada, Mitsuru Sugawara

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