A Novel Aggregation-Induced Emission-Based Electrochemiluminescence Aptamer Sensor Utilizing Red-Emissive Sulfur Quantum Dots for Rapid and Sensitive Malathion Detection by Yajun Wu, Dongxiao Ma, Xiaoli Zhu, Fangquan Xia

“…Here, we constructed a novel aggregation-induced emission (AIE) electrochemical aptamer (Apt) sensor based on red-emissive sulfur quantum dots (SQDs), which aimed at the rapid screening and quantitative detection of malathion. …”
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Enhanced Biomechanical Stability in Proximal Humeral Fractures: Finite Element Analysis of a Novel Endosteal Anatomical Support Nail for Improved Fixation in Elderly Patients by Jiawen Chen, Zhonghe Wang, Changda Li, Peiyu He, Zhongxuan Chen, Lijun Sun, Xiaoyan Cao, Na Tian, Xiang Dong, Peifu Tang, Hua Chen

“…Materials and Methods We developed a novel endosteal anatomical support nail (EASN) that integrates an endosteal torus construct into the proximal portion of the angle‐stable proximal humerus nail. …”
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Ca–Mg-Doped Surface-Modified Nano-Sized Ferrihydrite Powder Synthesized by Surfactant Mediation–Precipitation Technique: A Novel Super Adsorbent for Cations by M. Mohapatra, T. Padhi, S. Anand, B.K. Mishra

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A Novel Platelet Activating Factor Receptor Antagonist Reduces Cell Infiltration and Expression of Inflammatory Mediators in Mice Exposed to Desiccating Conditions after PRK by Salomon Esquenazi, Jiucheng He, Na Li, Nicolas G. Bazan, Isi Esquenazi, Haydee E. P. Bazan

“…To study the contribution of a novel PAF receptor antagonist LAU-0901 in the modulation of the increased inflammatory response in mice exposed to dessicating conditions (DE) after PRK. …”
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A novel scoring system based on magnetic resonance imaging for the prediction of the difficulty of ultrasound-guided high-intensity focused ultrasound ablation for uterine fibroids by Ying Zhang, Qian Wang, Yangyang Wang, Rong Ma, Min He, Lian Zhang

“…Objective To develop a novel scoring system based on magnetic resonance imaging (MRI) for predicting the difficulty of ultrasound-guided high-intensity focused ultrasound (USgHIFU) ablation for uterine fibroids.Materials and methods A total of 637 patients with uterine fibroids were enrolled. …”
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Connexin-Based Therapeutics and Tissue Engineering Approaches to the Amelioration of Chronic Pancreatitis and Type I Diabetes: Construction and Characterization of a Novel Prevascularized Bioartificial Pancreas by J. Matthew Rhett, Hongjun Wang, Heather Bainbridge, Lili Song, Michael J. Yost

“…We have invented technologies targeting the inflammatory response and poor vascularization: a Cx43 mimetic peptide that inhibits inflammation and a novel prevascularized tissue engineered construct. …”
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Synthesis of Novel Iono- and Photochromic Spiropyrans Derived from 6,7-Dihydroxy-8-Formyl-4-Methyl-2H-Chromene-2-One by Olga G. Nikolaeva, Alexey V. Tsukanov, Evgenii N. Shepelenko, Boris S. Lukyanov, Anatoly V. Metelitsa, Olga Yu. Kostyrina, Alexander D. Dubonosov, Vladimir A. Bren, Vladimir I. Minkin

“…Novel photochromic spiropyrans (SPPs) containing 6′-hydroxy group were synthesized and their spectral properties as well as abilities for complexation with metal ions studied. …”
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Active ingredients of traditional Chinese medicine inhibit NOD-like receptor protein 3 inflammasome: a novel strategy for preventing and treating heart failure by Ruifang Lin, Ruifang Lin, Yunfeng Yu, Lixin Du, Zehui Ding, Zehui Ding, Ziyan Wang, Ziyan Wang, Jiaming Wei, Jiaming Wei, Zhihua Guo, Zhihua Guo

“…The study aimed to explore the impact of NLRP3 inflammasome activation on the onset and progression of HF, and to review the current advancements in utilizing TCM active ingredients to inhibit the NLRP3 inflammasome for preventing and treating HF. This provides a novel perspective for the future development of precise intervention strategies targeting the NLRP3 inflammasome to prevent and treat HF.…”
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A Novel Modeling Technique for the Forecasting of Multiple-Asset Trading Volumes: Innovative Initial-Value-Problem Differential Equation Algorithms for Reinforcement Machine Learning by Mazin A. M. Al Janabi

“…In this paper, we do not propose a definitive one either, but we attempt to derive novel mathematical algorithms for the dynamic modeling of trading volumes during the closeout period from the perspective of multiple-asset portfolio(s), as well as for financial entities with different subsidiary firms and multiple agents. …”
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Case report: Deciphering the clinical significance of a novel partial BRCA1 exon 10 duplication in a patient with triple-negative breast cancer by Alice Faversani, Debora Manuelli, Davide Barteselli, Giulia Melloni, Carlo Santaniello, Luigi Corsaro, Luigi Corsaro, Davide Sacco, Davide Sacco, Davide Clerici, Laura Gargiulo, Fulvio Ferrara, Lucy Costantino

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Development of a novel, high-throughput imaged capillary isoelectric focusing-Western method to characterize charge heterogeneity of monoclonal antibody heavy and light chains by Gangadhar Dhulipala, Alanna Broszeit, Kun Lu, Nisha Palackal, Erica Pyles

“…ChromiCE was developed as an alternative approach to provide quantitative analysis, but the method is also labor intensive, requiring separation of the HC and LC by chromatography before imaged capillary isoelectric focusing (iCIEF) analysis. We thus developed a novel, automated high-throughput iCIEF-Western method to directly quantify the HC and LC charge variants with high sensitivity under denatured and reduced conditions. …”
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A Novel Student-Initiated International Emergency Medicine Competition: A Decade of Experience from the Khon Kaen University International Challenge of Emergency Medicine by Yui Okamura, Parames Ngeabngamsri, Ami Iwano, Thanachit Krikeerati, Kotaro Yanagisawa, Thanut Jansirirat, Moeko Ohkoshi, Tomonari Shimoda, Thomas Mayers, Praew Kotruchin, Pattarapong Makarawate

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Population genomics of a natural Cannabis sativa L. collection from Iran identifies novel genetic loci for flowering time, morphology, sex and chemotyping by Mahboubeh Mostafaei Dehnavi, Annabelle Damerum, Sadegh Taheri, Ali Ebadi, Shadab Panahi, George Hodgin, Brian Brandley, Seyed Alireza Salami, Gail Taylor

“…The identification of novel genetic loci associated with important traits suggests potential targets for future breeding programs. …”
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Bio-computational modeling, POM analysis and molecular dynamic simulation for novel synthetic quinolone and benzo[d][1,3]oxazine candidates as antimicrobial inhibitors by Doaa A. Elsayed, Mohamed E. Abdu, Mohammed A. Marzouk, Elsayed M. Mahmoud, Walaa H. El-Shwiniy, Andrew M. Spring, Wesam S. Shehab

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Antibacterial and Cytotoxic Evaluation of <i>Lespedeza cuneata</i> Extract Against Periodontal Pathogens and Human Gingival Cells: A Novel Option for Periodontal Therapy by Hyo-Ju Yoon, Gyoo-Cheon Kim, Seoul-Hee Nam

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A novel small RNA regulates Locus of Enterocyte Effacement and site-specific colonization of enterohemorrhagic Escherichia coli O157:H7 in gut by Runhua Han, Runhua Han, Ye Qian, Chenguang Zheng

“…This study has broader implications for understanding sRNA functions in spatiotemporal virulence control of EHEC and may provide novel strategies to prevent EHEC infections.…”
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Gene Mining and Genetic Effect Analysis Reveal Novel Loci, <i>TaZn-2DS</i> Associated with Zinc Content in Wheat Grain by Zhuangzhuang Hong, Zhankui Zeng, Jiaojiao Li, Xuefang Yan, Junqiao Song, Qunxiang Yan, Qiong Li, Yue Zhao, Chang Liu, Xueyan Jing, Chunping Wang

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Effectiveness of a novel training model for gastric endoscopic submucosal dissection training: a prospective observational study conducted at a single center in Japan by Takahito Toba, Tsuyoshi Ishii, Nobuyuki Sato, Akira Nogami, Aya Hojo, Ryo Shimizu, Ai Fujimoto, Takahisa Matsuda

“…In Japan, G-Master is a novel ex vivo gastric ESD training model. The effectiveness of training using G-Master is unknown. …”
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A Novel Approach to Study Real-Time Dynamic Optimization Analysis and Simulation of Complex Mine Logistics Transportation Hybrid System with Belt and Surge Links by Bai Xiao-ping, Zhao Yu-hong, Liu Ya-nan

“…This paper presents a novel approach to study real-time dynamic optimization analysis and simulation problems of complex mine logistics transportation hybrid system, which can be used to make optimization design for this kind of complex hybrid system. …”
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Development and Evaluation of a Novel Radiotracer 125I-rIL-27 to Monitor Allotransplant Rejection by Specifically Targeting IL-27Rα by Shanshan Zhao, Qian Liu, Feng Gao, Guihua Hou

“…Therefore, we developed a novel radiotracer (iodine-125-labeled recombinant IL-27) to evaluate the advantage in the targeting and imaging of allograft rejection. …”
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