Cross-species comparison of AlphaFold-derived G protein-coupled receptor structures reveals novel melatonin-related receptor in Neurospora crassa. by Cathryn S D Maienza, Guillaume Lamoureux, Kwangwon Lee

“…This proof-of-concept study underscores the potential of N. crassa as a model organism for circadian research and demonstrates the broader applicability of using AlphaFold2, especially when sequence similarity does not lead to candidate genes, for identifying novel receptors across different species.…”
Get full text

An In Vitro Pilot Study Comparing the Novel HemoClear Gravity-Driven Microfiltration Cell Salvage System with the Conventional Centrifugal XTRA™ Autotransfusion Device by Anneloes Hoetink, Sabine F. Scherphof, Frederik J. Mooi, Paul Westers, Jack van Dijk, Sjef J. van de Leur, Arno P. Nierich

“…To achieve this, current gold standard autotransfusion devices should be complemented with widely available, cost-efficient, and time-efficient devices. The novel HemoClear cell salvage device (HemoClear BV, Zwolle, Netherlands), a gravity-driven microfilter, potentially is widely employable. …”
Get full text

Assessment of improvement in functional outcomes between a novel knee replacement design and conventional designs in 240 patients: a randomized controlled trial by Tero Irmola, Aleksi Reito, Jarmo Kangas, Antti Eskelinen, Mika Niemeläinen, Ville M Mattila, Teemu Moilanen

“…The aim of our RCT was to investigate the functional outcomes of a novel TKA implant design compared with 2 conventional TKA designs. …”
Get full text

Utilizing a novel fecal sampling method to examine resistance of the honey bee (Apis mellifera) gut microbiome to a low dose of tetracycline by Casey L. Gregory, Emma L. Bradford, Richard D. Fell, David C. Haak, Lisa K. Belden

Get full text

Identification and expression of the target gene slc24a2 of oar-mir-377 and its novel snps effects on wool traits in sheep by Huaqian ZHOU, Hua YANG, Wenhua FAN, Hanyulu YANG, Zongsheng ZHAO, Qian YU, Yonglin YANG, Wenzhe ZHANG

Get full text

Novel Development to the Theory of Dombi Exponential Aggregation Operators in Neutrosophic Cubic Hesitant Fuzzy Sets: Applications to Solid Waste Disposal Site Selection by Ateeq Ur Rehman, Muhammad Gulistan, Nasreen Kausar, Sajida Kousar, Mohammed M. Al-Shamiri, Rashad Ismail

Get full text

Preparation and Bioactivity Properties of a Novel Composite Membrane of Fructose Mediated β-Tricalcium Pyrophosphate/(Polyethylene Glycol/Chitosan) for Guided Tissue Regeneration by Jian-Wen Wang, Min-Hsiung Hon, Yi-Ming Kuo, Mei-Hui Chung

“…A novel composite membrane of β-tricalcium pyrophosphate (β-TCP) and fructose- (F-) mediated chitosan/poly(ethylene glycol) (CS/PEG) was prepared by thermally induced phase separation technique. …”
Get full text

Half-Covered ‘Glitter-Cake’ AM@SE Composite: A Novel Electrode Design for High Energy Density All-Solid-State Batteries by Min Ji Kim, Jin-Sung Park, Jin Woong Lee, Sung Eun Wang, Dowoong Yoon, Jong Deok Lee, Jung Hyun Kim, Taeseup Song, Ju Li, Yun Chan Kang, Dae Soo Jung

“…Highlights A novel electrode design for high energy density all-solid-state batteries (ASSBs) is realized through the control of nano- and microstructures. …”
Get full text

Case report: Novel ACTN4 variant of uncertain significance in a pediatric case of steroid-resistant nephrotic syndrome requesting kidney transplantation by Ignacio Alarcón, Carolina Peralta, Francisco Cammarata-Scalisi, Maykol Araya Castillo, Francisco Cano, Francisco Cano, Angélica Rojo, María Luisa Ceballos, María Luisa Ceballos, Paola Krall, Paola Krall

“…Exome sequencing identified a novel variant of uncertain significance (VUS), ACTN4 c.625_633del that predicted the in-frame deletion p.L209_E211del in a highly conserved functional domain. …”
Get full text

Novel N-quaternary coumarin-3-yl-imidazo[1,2-a]pyridines as fluorescent hybrids: Their synthesis and biological evaluation in cancer cells by Karla Armendariz-Barrientos, Luis A. Pérez, Selene Lagunas-Rivera, Yolanda Alcaraz-Contreras, Marco A. García-Revilla, Heriberto Prado-Garcia, Rocío García-Becerra, Miguel A. Vazquez

“…Hybrid coumarin-3-yl-imidazo[1,2-a]pyridines were used to synthesize novel derivatives of quaternary salts 5a-c and 6a,b, employing ethyl iodide and benzyl bromide as alkylating agents. …”
Get full text

The enigmatic SLC26A6 multifunctional anion transporter: recent advances in structure-function relationship, pathophysiological significance and novel pharmacological inhibitors by Ursula E. Seidler

Get full text

Disulfidptosis-related gene SLC3A2: a novel prognostic biomarker in nasopharyngeal carcinoma and head and neck squamous cell carcinoma by Xinyi Zhang, Yiqi Lin, Liang Shi, Aixia Zhai, Chao Wu, Qian-Ying Zhu

“…Recently, disulfidoptosis, a novel form of cell death, has been proposed. Several studies in recent years have extensively investigated the function of the disulfidoptosis-related SLC7A11 gene in cancer, but the role of its partner protein, SLC3A2, remains unknown unclear in NPC.MethodsGEO database analysis confirmed SLC3A2's prognostic impact on nasopharyngeal carcinoma. …”
Get full text

A novel framework unveiling the importance of heterogeneous selection and drift on the community structure of symbiotic microbial indicator taxa across altitudinal gradients in amphibians by Jin Zhou, Zhidong Liu, Sishuo Wang, Jing Li, Lin Zhang, Ziyan Liao

“…Altogether, our modeling framework is a robust and valuable tool that further enlarges our insight into microbiota community assembly.IMPORTANCEDistinguishing the drivers regulating microbial community assembly is essential in microbial ecology. We propose a novel modeling framework to partition the relative contributions of each individual or group of microbial DSUs and DTUs into different underpinning mechanisms. …”
Get full text

Inter-laboratory ring test for environmental DNA extraction protocols: implications for marine megafauna detection using three novel qPCR assays by Lauren Kelly Rodriguez, Lorenzo De Bonis, Jack McKee, James A. McKenna, Teddy Urvois, Eleonora Barbaccia, Eileen Dillane, Caterina Lanfredi, Helene Hjellnes, Armelle Jung, Enrico Villa, Arianna Azzellino, Jon-Ivar Westgaard, Erwan Quéméré, Bettina Thalinger

“…Extracts were returned to the lysates’ respective laboratories of origin for measurements of total DNA concentration, as well as quantitative PCR using three novel species-specific assays for marine megafauna. …”
Get full text

Application of Novel Amino-Functionalized NZVI@SiO2 Nanoparticles to Enhance Anaerobic Granular Sludge Removal of 2,4,6-Trichlorophenol by Zeyu Guan, Jinquan Wan, Yongwen Ma, Yan Wang, Yajie Shu

“…A novel amino-functionalized silica-coated nanoscale zerovalent iron (NZVI@SiO2-NH2) was successfully synthesized by using one-step liquid-phase method with the surface functionalization of nanoscale zerovalent iron (NZVI) to enhance degradation of chlorinated organic contaminants from anaerobic microbial system. …”
Get full text

Device endothelialization and morphology assessments at 1 year using computed tomography angiography: comparison of traditional with novel puncturable atrial septal defect occluders by Yanxing Fang, Kai Hou, Dawei Lin, Daxin Zhou, Wenzhi Pan, Junbo Ge

“…This study aimed to assess the endothelialization and morphology of a novel puncturable ASD occluder (ReAces) compared with traditional occluders 1 year post-implantation using computed tomography angiography (CTA). …”
Get full text

Individual management and prognostic assessment for long-term outcomes using a novel classification system of craniopharyngiomas: a retrospective study of single institution by Sen Zhang, Bo Xie, Yi He, Xingshu Zhang, Gu Gong, Mingrui Li, Yinhua Chen, Guodong Tang, Chi Zhang, Chaoying Qin, Qing Liu

Get full text

A Novel Optimization Method Using the Box–Behnken Design Integrated with a Back Propagation Neural Network–Genetic Algorithm for Hydrogen Purification by Nannan Zhang, Sumeng Hu, Qianqian Xin

“…To explore a better optimization solution, a novel optimization method using machine learning with a back propagation neural network (BPNN) was then proposed, and a kind of heuristic algorithm–genetic algorithm (GA) was introduced to enhance the architecture of the BPNN. …”
Get full text

Equilibrium Isotherms, Kinetics, and Thermodynamic Mechanisms of a Novel Polyacrylamide-Strychnos potatorum Seed-Derived Activated Carbon Composite for Aqueous Hardness Removal by Yohan L. N. Mathota Arachchige, T. D. Fernando

Get full text

Margaret Markwick, Deborah Denenholz Morse and Regenia Gagnier, eds, The Politics of Gender in Anthony Trollope’s Novels. New Readings for the Twenty-First Century by Laurent Bury

Get full text