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Case report: Novel multi-exon homozygous deletion of ZBTB24 causes immunodeficiency, centromeric instability, and facial anomalies syndrome 2
Published 2025-01-01“…These results indicated that this novel multi-exon deletion variant of ZBTB24 may be the genetic etiology of ICF2. …”
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3782
Conversion therapy strategy: A novel GPC3-targeted multimodal organic phototheranostics platform for mid-late-stage hepatocellular carcinoma
Published 2025-02-01“…High-sensitivity FLI/MRI precisely delineates tumor boundaries, providing real-time surgical navigation and prognosis assessment. This novel probe offers a feasible and effective treatment option for advanced HCC.…”
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3783
Unmasking The Hidden Clues: Shedding Light On The Potential Of Novel Biomarkers In Endometrial Cancer, Comparing RT-Qpcr And Immunohistochemical Analysis In Clinical Specimens
Published 2025-01-01“… Objective: The objective of this study was to compare the diagnostic accuracy of RT-qPCR in endometrial cancer using novel biomarkers in clinical specimens, keeping immunohistochemical analysis as the gold standard. …”
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Novel Fast-Setting and Mechanically-Strong Calcium Phosphate Pulp-Capping Cement with Metformin Release to Enhance Dental Pulp Stem Cells
Published 2024-12-01“…These findings suggest that the novel CPCC-Met demonstrates promise as a fast-setting, cost-effective pulp-capping material, offering metformin delivery to enhance dentin repair.…”
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3788
Actively protective combinatorial analysis: A scalable novel method for detecting variants that contribute to reduced disease prevalence in high-risk individuals
Published 2025-06-01“…We present a novel method for routinely identifying disease resilience associations that offers powerful insights for the discovery of a new class of disease protective targets. …”
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Silencing hepatic PCSK9 via novel chimeric AAV8 mitigates the progression of atherosclerosis by inhibiting inflammation in ApoE−/− mice
Published 2025-03-01“…Proprotein convertase subtilisin/kexin type 9 (PCSK9), predominantly expressed in the liver, plays a crucial role in lipid regulation and atherosclerosis progression. Here, we developed a novel chimeric AAV8.P-PCSK9 short hairpin RNA (shRNA) vector that incorporates a cross-species specific shRNA targeting PCSK9 to assess its effects on lipid levels and atherosclerosis in mice. …”
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Evaluation of deceased-donor kidney offers: development and validation of novel data driven and expert based prediction models for early transplant outcomes
Published 2025-01-01“…In summary, we developed novel statistical models that represent current clinical consensus and are tailored to the older deceased donor population. …”
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The Super Anti-Apoptotic Factor Bcl-xFNK: A Novel Mutant of Rat Bcl-Xl with a Gain-of-Function Phenotype
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3797
Synthesis and In Vitro Antioxidant Evaluation of Some Novel 4, 5-Dihydro-1H, 2, 4-triazol-5-one Derivatives
Published 2010-01-01“…In this study, thirteen novel 4,5-dihydro-1H-1,2,4-triazol-5-one derivatives were synthesized and characterized by elemental analyses and IR, 1H NMR,13C NMR and UV spectral data. …”
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Neural Network Based Active Disturbance Rejection Control of a Novel Electrohydraulic Servo System for Simultaneously Balancing and Positioning by Isoactuation Configuration
Published 2016-01-01“…To satisfy the lightweight requirements of large pipe weapons, a novel electrohydraulic servo (EHS) system where the hydraulic cylinder possesses three cavities is developed and investigated in the present study. …”
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Novel Procedures for Evaluating Autism Online in a Culturally Diverse Population of Children: Protocol for a Mixed Methods Pathway Development Study
Published 2025-02-01“…ConclusionsThe CHATA project aims to establish a novel, culturally sensitive, equitable, and accurate online autism assessment pathway. …”
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A novel fluorescence sensor for milk clotting enzyme chymosin using peptide as substrate and covalent organic framework nanosheet as fluorescence quencher
Published 2024-11-01“…Herein, we proposed a novel fluorometric assay for chymosin determination. …”
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