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3741
Enhancing the Performance of Novel Archimedes Spiral Hydrokinetic Turbines Utilizing Blade Winglets in Deep-Sea Power Generation for Autonomous Underwater Vehicles
Published 2025-01-01“…The Archimedes spiral hydrokinetic turbine (ASHT), as a novel type of horizontal-axis hydrokinetic turbine, has emerged as a promising solution for the harnessing of localized energy in the deep sea to power AUVs. …”
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Development of novel nomograms for predicting prostate cancer in biopsy-naive patients with PSA < 10 ng/ml and PI-RADS ≤ 3 lesions
Published 2025-01-01“…PurposeTo develop novel nomograms for predicting prostate cancer (PCa) and clinically significant prostate cancer (csPCa) in patients with prostate-specific antigen (PSA) < 10 ng/ml and PI-RADS v2.1 score ≤ 3.MethodsWe retrospectively collected data from 327 men with PSA < 10 ng/ml and PI-RADS score ≤ 3 from June 2020 to June 2024 in our hospital. …”
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3744
Identification and the molecular mechanism of novel duck liver-derived anti-inflammatory peptides in lipopolysaccharide-induced RAW264.7 cell model
Published 2024-11-01“…In this study, 10 novel anti-inflammatory peptides were identified from duck liver, and their molecular mechanism was demonstrated based on machine learning and molecular docking. …”
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Rearing in a Physically Enriched Environment Affects Shoaling and Stress Responses of Zebrafish (<i>Danio rerio</i>) Exposed to Novel Conditions
Published 2025-01-01“…The impact of enrichment on stress reduction in zebrafish (<i>Danio rerio</i>) exposed to a novel environment was assessed. Four control shoals (CTRL) and five treated shoals (TRT), each with eight fish, were observed; in TRT tanks, a PVC pipe was included (three-way tube, 11.7 × 4 cm) as enrichment for 90 days. …”
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A Novel Rat Infant Model of Medial Temporal Lobe Epilepsy Reveals New Insight into the Molecular Biology and Epileptogenesis in the Developing Brain
Published 2024-01-01“…Although several adult rat models of medial temporal lobe epilepsy (mTLE) have been described in detail, our knowledge of mTLE epileptogenesis in infant rats is limited. Here, we present a novel infant rat model of mTLE (InfRPil-mTLE) based on a repetitive, triphasic injection regimen consisting of low-dose pilocarpine administrations (180 mg/kg. i.p.) on days 9, 11, and 15 post partum (pp). …”
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SDZ MRL 953, A Novel Synthetic Lipid a Analogue, Induces Tolerance to the Lethal Effects of Endotoxin and Enhances Nonspecific Immunity
Published 1992-01-01“…An attractive alternative appears to be the induction of hyporesponsiveness to LPS by synthetic lipid A analogues. SDZ MRL 953, a novel prototype of lipid A analogues. was examined for its ability to induce early-phase tolerance against experimental endotoxemia in mice following single or multiple administrations 2, 24, or 72 h before challenge. …”
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Photodynamic therapy with a novel photosensitizer inhibits DSS-induced ulcerative colitis in rats via the NF-κB signaling pathway
Published 2025-01-01“…IntroductionUlcerative colitis (UC) is an inflammatory bowel disease characterized by inflammation and ulceration of the digestive tract.MethodsPhotodynamic therapy (PDT) with a novel photosensitizer LD4 was used to treat UC rat models to explore the therapeutic effect and mechanism of LD4-PDT on UC. 16S ribosomal RNA was used to detect the composition of Gut microbiota.ResultsOur findings indicate that LD4-PDT could protect the integrity of the colonic mucosa, alleviate the inflammatory response and promote the healing of colonic mucosa. …”
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Effectiveness of a novel amine + zinc + fluoride toothpaste in reducing plaque and gingivitis: results of a six-month randomized controlled trial
Published 2025-02-01“…Conclusions The amine + zinc + fluoride toothpaste significantly improved measures of plaque (12× more effective) and gingivitis (5× more effective) in comparison to a standard fluoride toothpaste, suggesting that the novel formulation with antibacterial active ingredients amine and zinc facilitates more effective plaque removal, and promotes gingival health. …”
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A Novel Hybrid Model for Credit Risk Assessment of Supply Chain Finance Based on Topological Data Analysis and Graph Neural Network
Published 2025-01-01“…This study proposes a novel hybrid Topological Data Analysis (TDA) and Graph Neural Network (GNN) to optimize credit risk assessment in SCF. …”
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