GNA15 predicts poor outcomes as a novel biomarker related to M2 macrophage infiltration in ovarian cancer by Qin Liu, Qin Liu, Yabing Sun, Yabing Sun, Tao Zhang, Wanrun Lin, Jing Zhang, Huijuan Zhang, Huijuan Zhang, Wenxin Zheng, Hong Xu, Hong Xu, Feng Zhou, Feng Zhou

“…This study aims to establish a novel prognostic signature and identify M2-like TAM-related biomarkers in OC using RNAseq-based transcriptome analysis.MethodsPrognostic M2-like TAM-related genes were identified through univariate Cox regression, consensus clustering, and LASSO regression. …”
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Multi-ancestry genome-wide meta-analysis with 472,819 individuals identifies 32 novel risk loci for psoriasis by Min Zhang, Wenting Su, Jiahui Deng, Bin Zhai, Gaizhi Zhu, Ran Gao, Qi Zeng, Jinming Qiu, Ziqing Bian, He Xiao, Guoming Luan, Renxi Wang

“…Results We identified 74 genome-wide significant loci for psoriasis. Of 74 loci, 32 were novel psoriasis risk loci. Across 74 loci, 801 likely causal genes are indicated and 164 causal genes are prioritized. …”
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Design and Numerical Analysis of a Novel Rectangular PCF (R-PCF)-Based Biochemical Sensor (BCS) in the THz Regime by Abdullah Al-Mamun Bulbul, Abbas Z. Kouzani, M. A. Parvez Mahmud, Abdullah-Al Nahid

“…A novel PCF-based sensor has been presented in this paper to sense different chemicals and biocomponents. …”
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A Novel Spine Fixation System Made Entirely of Carbon-Fiber-Reinforced PEEK Composite: An In Vitro Mechanical Evaluation by Ofir Uri, Yoram Folman, Gil Laufer, Eyal Behrbalk

“…This study tests the mechanical properties of a novel spine fixation system made entirely of carbon-fiber-reinforced PEEK (CFR-PEEK) composite material (CarboClear System, CarboFix Orthopedics Ltd., Israel). …”
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Dysregulated Expression and Methylation Analysis Identified TLX1NB as a Novel Recurrence Marker in Low-Grade Gliomas by Hongzhou Duan, Zuozhen Yang, Chen Li, Jiayong Zhang, Shengli Shen, Changwei Yuan, Yingjin Wang

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Novel Heronian mean based $ m $-polar fuzzy power geometric aggregation operators and their application to urban transportation management by Ghous Ali, Kholood Alsager

“…This study was mainly devoted to introducing three novel aggregation operators (AGOs) for multi-criteria decision-making (MCDM) based on generalized geometric Heronian mean (GGHM) operations comprise the concept of $ m $F sets. …”
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Serum Lactate Dehydrogenase Is a Novel Predictor for the Severity in the Patients With MAFLD: A Cross-Sectional Study in Hefei, China by Yu L, Bao S, Zhu F, Xu Y, Zu F, Liu Y, Jiang R, Chen S, Chen W

“…Logistic regression showed that LDH was significantly and positively correlated with MAFLD, B.MASH, MASH, at-risk MASH, fibrosis grade ≥ 1, fibrosis grade ≥ 2 and fibrosis grade ≥ 3.Conclusion: Increased LDH levels were significantly and independently associated with the presence and severity of metabolic syndrome and MAFLD, indicating that LDH could be used as a novel biomarker and clinical predictor of severity of metabolic syndrome and MAFLD.Keywords: lactate dehydrogenase, obesity, metabolic syndrome, inflammation, metabolic associated fatty liver disease, (MAFLD)…”
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A Novel Case Base Reasoning and Frequent Pattern Based Decision Support System for Mitigating Software Risk Factors by Muhammad Asif, Jamil Ahmed

“…This paper presents a novel model which identifies the relationship between risk factors and mitigations automatically by using intelligent Decision Support System (DSS). …”
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A Novel Molecularly Imprinted Electrochemiluminescence Sensor Based on Mxene Quantum Dots for Selective Detection of Oseltamivir in Biological Samples by Wei Guo, Shiqiang Yan, Chaoqiang Xiao, Dayong Shi, Qing Hua, Xiaowen Hao, Wenjuan Zhang, Xuming Zhuang

“…In this work, an ultrasensitive, simple, and novel electrochemiluminescence (ECL) sensor combined with molecularly imprinted polymers (MIP-ECL) based on a graphene-like two-dimensional material, Mxene quantum dots (MQDs) was constructed to selectively detect oseltamivir. …”
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Planning and Scheduling Process for a Grid-Connected Microgrid Based on Renewable Energy Sources by a Novel Fuzzy Method by Zhao Lijun, Li Qingsheng, Ding Guanhua

“…In the present work, a novel programming method is proposed for energy management and optimization of operational expenses over a grid-connected microgrid (MG). …”
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WeiFu: A Novel Pan-Cancer Driver Gene Identification Method Using Incidence-Weighted Mutation Scores by Yanjie Ren, Azlan Mohd Zain, Yan Zhang, Rozita Abdul Jalil, Mahadi Bahari, Norfadzlan Bin Yusup, Mazlina Abdul Majid, Azurah A. Samah, Didik Dwi Prasetya, Nurhafizah Moziyana Mohd Yusop

“…This study addresses this gap by integrating pan-cancer genomic somatic mutation data and introducing a novel mutation weight fusion (WeiFu) score calculation method. …”
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Identification of novel saltiness/saltiness enhancing peptides in egg proteins: Molecular docking, action mechanism and in vitro activity validation by Yaxin Cao, Linyuezhi Yan, Di Liu, Qian Zhang, Wenzhu Zhao, Lin Yuan, Yiding Yu, Zhipeng Yu

“…In this study, novel saltiness/saltiness enhancing peptides VESQTNGIIR, NQITKPNDVY, and DEDTQAMP were identified from the hen egg proteins via virtual enzymatic, molecular docking, and electronic tongue analysis. …”
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Machine learning-based identification and validation of amino acid metabolism related genes as novel biomarkers in chronic kidney disease by Guoqing Zhang, Hongyan Luo, Xiaohua Lu, Yonghua Liu, Mei Wang, Bo Li, Haixia Lu, Yali Zheng

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Antibacterial Effects of the Novel Blue Laser and Erbium Chromium Laser on Enterococcus Faecalis in Root Canal Dentin with Different Thicknesses by Seyedeh Sareh Hendi, Erfan Ahmadyani, Mohammad Yousef Alikhani, Maryam Farhadian, Alireza Mirzaei

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Valorization of vermicompost with bacterial fermented chicken feather hydrolysate for the yield improvement of tomato plant: A novel organic combination by Ishita Biswas, Debasis Mitra, Ansuman Senapati, Debanjan Mitra, Sourav Chattaraj, Murshed Ali, Goutam Basak, Periyasamy Panneerselvam, Pradeep K. Das Mohapatra

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Identification of a novel TOP2B::AFF2 fusion gene in B-cell acute lymphoblastic leukemia by Tao Liu, Yang Wang, Xi-Zhou An, Jiaqi Liu, Yuqin Wu, Yan Xiang, Yong-Jie Zhang, Lan Huang, Jia-Cheng Li, Yu-Zhuo-Pu Li, Jie Yu

“…Abstract Genetic alterations play a pivotal role in leukemic clonal transformation, significantly influencing disease pathogenesis and clinical outcomes. Here, we report a novel fusion gene and investigate its pathogenic role in acute lymphoblastic leukemia (ALL). …”
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Genome-wide association studies identify two novel BMP15 mutations responsible for an atypical hyperprolificacy phenotype in sheep. by Julie Demars, Stéphane Fabre, Julien Sarry, Raffaella Rossetti, Hélène Gilbert, Luca Persani, Gwenola Tosser-Klopp, Philippe Mulsant, Zuzanna Nowak, Wioleta Drobik, Elzbieta Martyniuk, Loys Bodin

“…Thus, we have identified two novel mutations in the BMP15 gene associated with increased LS and OR. …”
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Ecuadorian Cacao Mucilage as a Novel Culture Medium Ingredient: Unveiling Its Potential for Microbial Growth and Biotechnological Applications by Tania María Guzmán-Armenteros, Luis Santiago Guerra, Jenny Ruales, Luis Ramos-Guerrero

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Unsupervised detection of novel SARS-CoV-2 mutations and lineages in wastewater samples using long-read sequencing by Ignacio Garcia, Rasmus K. Riis, Line V. Moen, Andreas Rohringer, Elisabeth H. Madslien, Karoline Bragstad

“…HERCULES identifies and quantifies mutations and lineages without requiring database-guided deconvolution, enhancing the detection of novel variants. We evaluated HERCULES on Norwegian wastewater samples collected from July 2022 to October 2023 as part of a national pilot on WBE of SARS-CoV-2. …”
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Nanotherapeutic smart approaches for combating Alzheimer’s disease and overcoming existing obstacles: A novel eco-friendly green approach by Ahmed M. Almehdi, Doha H. Aboubaker, Rania Hamdy, Ali El-Keblawy

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