Identification of multicohort-based predictive signature for NMIBC recurrence reveals SDCBP as a novel oncogene in bladder cancer by Chen Zhang, Hubin Yin, Tinghao Li, Junrui Chen, Weiyang He, Ke Ren, Bo Li, Xudong Liu

“…Traditional clinical characteristics alone are inadequate for accurately assessing the risk of NMIBC recurrence, necessitating the development of novel predictive tools.Methods We analyzed microarray data of NMIBC samples obtained from the ArrayExpress and GEO databases. …”
Get full text

Collaborative interfacial shear capacity of adhesive bonding and novel shooting nail for steel plate strengthening concrete structures by Mingxue Xu, Lei Ren, Zheng Shi, Xiaogang Liu

“…Abstract Shooting nail is a novel fastening approach for the reinforcement of concrete bridges and building structures using bonding steel plates, offering enhanced construction efficiency compared to traditional chemical anchor bolts. …”
Get full text

Unveiling inverted D genes and D-D fusions in human antibody repertoires unlocks novel antibody diversity by Ponraj Prabakaran, Abhinav Gupta, Sambasiva P. Rao, Deepak Rajpal, Maria Wendt, Yu Qiu, Partha S. Chowdhury

Get full text

A comprehensive transcriptional reference for severity and progression in spinal cord injury reveals novel translational biomarker genes by Rubén Grillo-Risco, Marta R. Hidalgo, Beatriz Martínez-Rojas, Victoria Moreno-Manzano, Francisco García-García

Get full text

Protein C Deficiency Caused by a Novel Mutation in the PROC Gene in an Infant with Delayed Onset Purpura Fulminans by Mariam S. Al Harbi, Ayman W. El-Hattab

“…Protein C level was less than 10% and PROC gene sequencing identified a novel homozygous missense mutation, c.1198G>A (p.Gly400Ser). …”
Get full text

Development of RT-PCR Assays for Simple Detection and Identification of Sabin Virus Contaminants in the Novel Oral Poliovirus Vaccines by Olga Singh, Hasmik Manukyan, Erman Tritama, Shwu-Maan Lee, Jerry P. Weir, Majid Laassri

“…These vaccines are derived from three attenuated Sabin strains of poliovirus, which can revert within the first week of replication to a neurovirulent phenotype, leading to sporadic cases of vaccine-associated paralytic poliomyelitis (VAPP) among vaccinees and their contacts. A novel OPV2 vaccine (nOPV2) with enhanced genetic stability was developed recently; type 1 and type 3 nOPV strains were engineered using the nOPV2 genome as a backbone by replacing the capsid precursor polyprotein (P1) with that of Sabin strains type 1 and type 3, respectively. …”
Get full text

A Novel Method for Identifying Resonance Frequency Band in Weak Bearing Fault Diagnosis of Electric Driving System by Cong Yue, Yu Zhu, Ping Cheng, Bei Wang, Kai Wang

“…Because of the uncertainty of the structure and environment of the electric driving system (EDS), the fault signature of the rotating mechanism is complicated. A novel method based on Hilbert transform with modified fast kurtogram (HTMFK), which is used for identifying the bearing faults in the EDS, is proposed. …”
Get full text

Novel intelligent MPP tracker and sliding mode control for decentralized street lighting systems using photovoltaic energy by Hussain Attia, Ali Al-Ataby, Maen Takruri, Amjad Omar

Get full text

Novel Mutation in the PKHD1 Gene Diagnosed Prenatally in a Fetus with Autosomal Recessive Polycystic Kidney Disease by Pankaj Thakur, Paul Speer, Aleksandar Rajkovic

Get full text

The costs and logistics of distributing ‘forest packs’ containing novel vector control tools to forest-exposed populations in Cambodia by Joshua Yukich, Dyna Doum, David J. McIver, Jason H. Richardson, Siv Sovannaroth, Neil F. Lobo, Allison Tatarsky

Get full text

Identification of ALEKSIN as a novel multi-IRF inhibitor of IRF- and STAT-mediated transcription in vascular inflammation and atherosclerosis by Aleksandra Antonczyk, Katarzyna Kluzek, Natalia Herbich, Mahdi Eskandarian Boroujeni, Bart Krist, Dorota Wronka, Anna Karlik, Lukasz Przybyl, Adam Plewinski, Joanna Wesoly, Hans A. R. Bluyssen

“…Together, this suggests that ALEKSIN represents a novel class of multi-IRF inhibitors, which inhibits IRF-, STAT-, and NF-κB-mediated transcription and could offer great promise for the treatment of CVDs. …”
Get full text

A novel approach for agricultural carbon emission reduction by integrating fermatean neutrosophic set with WINGS and AHP-EWM by Kecheng Zhang, Zhicheng Chen, Yawen Wang

“…This research advances the field by offering a novel theoretical model for complex decision-making under uncertainty, deepening the understanding of agricultural carbon reduction dynamics, and providing actionable insights for sustainable development.…”
Get full text

A Novel Active Disturbance Rejection Control with a Super-Twisting Observer for the Rocket Launcher Servo System by Di-Fen Shi, Yuan-Long Hou, Xiao-Hui Gu, Run-Min Hou

“…In this paper, a novel active disturbance rejection control (NADRC) with a super-twisting extended state observer (SESO) is utilized in the rocket launcher servo system. …”
Get full text

Bio-inspired novel choline ester ionic liquid gel polymer electrolytes for safer lithium-ion batteries by Tommy Hoong Wy Lee, Phei Li Lau, Ianatul Khoiroh

“…Ionic liquids (ILs) present an alternative, offering low volatility and high stability. This study explores novel choline-based ILs incorporated into a polymer matrix to synthesise ionic liquid gel polymer electrolytes (GPEs). …”
Get full text

Novel Action of FSH on Stem Cells in Adult Mammalian Ovary Induces Postnatal Oogenesis and Primordial Follicle Assembly by Deepa Bhartiya, Seema Parte, Hiren Patel, Kalpana Sriraman, Kusum Zaveri, Indira Hinduja

“…This emerging understanding and further research in the field will help evolving novel strategies to manage ovarian pathologies and also towards oncofertility.…”
Get full text

Mitigating climate change with financial investments: exploring sustainable investment strategies in a novel experimental investment paradigm by Hulda Karlsson-Larsson, Arvid Erlandsson, Joakim Sandberg, Daniel Västfjäll

“…The relative use of these strategies was tested within a novel investment paradigm, aiming to artificially create a trade-off between financial payoffs (money maximization), environmental purity (exclusion), and environmental impact (inclusion). …”
Get full text

Uncovering the Hydrocracking Efficiency of Iron-Based Catalysts: A Novel Approach to Asphaltene Transformation in Iranian Heavy Oil by Muzaffer Yaşar, Savaş Gürdal, Kadir Yılmaz

Get full text

Novel Framework for Artificial Bubble Image Generation and Boundary Detection Using Superformula Regression and Computer Vision Techniques by Pavel Mikushin, Nickolay Martynenko, Irina Nizovtseva, Ksenia Makhaeva, Margarita Nikishina, Dmitrii Chernushkin, Sergey Lezhnin, Ilya Starodumov

“…This study proposes a novel framework to address these limitations. Using Superformula parameter regression, we introduce an advanced border detection method for accurately identifying gas inclusions and complex-shaped objects in multiphase environments. …”
Get full text

Assessment of ecological environment quality and their drivers in urban agglomeration based on a novel remote sensing ecological index by Fangyuan Lu, Chen Zhang, Haoyu Cao, Xibin Wang, Tong Zheng, Zhenfang Huang

Subjects: Get full text

A novel biomarker of COVID-19: MMP8 emerged by integrated bulk RNAseq and single-cell sequencing by Zhenguo Liu, Shunda Wang

Get full text