Novel role of microphthalmia-associated transcription factor in modulating the differentiation and immunosuppressive functions of myeloid-derived suppressor cells by Yoon Kyung Jeon, Aram Lee, Haesun Park, Soyoung Lim, Jihyun Lim, Jaemoon Koh, Young Yang, Myeong-Sok Lee, Jong-Seok Lim

“…Furthermore, IHC staining of human tumor tissues revealed that MITF+ MO-MDSCs are more frequently observed in tumor tissues than in tumor-free draining lymph nodes obtained from patients with cancer.Conclusions Our results indicate that MITF regulates the differentiation and function of MDSCs and can be a novel therapeutic target for modulating MDSC activity in immunosuppressive TMEs.…”
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A Novel Technique to Compute the Revisit Time of Satellites and Its Application in Remote Sensing Satellite Optimization Design by Xin Luo, Maocai Wang, Guangming Dai, Xiaoyu Chen

“…This paper proposes a novel technique to compute the revisit time of satellites within repeat ground tracks. …”
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A Novel Picture Fuzzy n-Banach Space with Some New Contractive Conditions and Their Fixed Point Results by Awais Asif, Hassen Aydi, Muhammad Arshad, Zeeshan Ali

“…The purpose of this manuscript is to present some novel contractive conditions based on NPF. By using these contractive conditions, we explore some fixed point theorems in a picture fuzzy n-Banach space (BPF). …”
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Effects of thermal aging on the performance of ordinary and novel superhydrophobic and oleophobic ultra-fine dry powder extinguishing agent by Yurong Liu, Ruiyu Chen, Wang Zhixuan, Rui Zhang, Hongling Jing, Daheng Yu, Renming Pan

“…This study investigates the effects of thermal aging cycles on various parameters of ordinary dry powder extinguishing agent (ODPEA) and novel superhydrophobic and oleophobic ultra-fine dry powder extinguishing agent (SHOU DPEA), including surface microscopic morphology, D90 (the diameter at which 90% of the cumulative volume of particles are equal to or smaller than this value), chemical structure, hydrophobic and oleophobic angles, flowability, extinguishing time and effectiveness. …”
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Autosomal Recessive Non-Syndromic Hearing Loss: A Case Report with a Novel TRIOBP Gene Variant by Shweta Jangam, Manju Kurup, Preeti Arora, Shruti Jawale, Prashant Duraphe, Sanjay Gupte

“… In the present case report, we have found a novel variant for TRIOBP in a patient with congenital hearing loss. …”
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Novel Mechanisms Modulating Palmitate-Induced Inflammatory Factors in Hypertrophied 3T3-L1 Adipocytes by AMPK by Naru Morita, Toshio Hosaka, Atsuko Kitahara, Toshitaka Murashima, Hirohisa Onuma, Yoshikazu Sumitani, Kazuto Takahashi, Toshiaki Tanaka, Takuma Kondo, Hitoshi Ishida

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A Novel Hypothesis for Migraine Disease Mechanism: The Creation of a New Attractor Responsible for Migraine Disease Symptoms by Elham Baradari, Farnaz Garehdaghi, Yashar Sarbaz

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Research on the Load Bearing and Impact Resistance of a Novel Structure Exhibiting Both Positive and Negative Poisson’s Ratios by Xidong Zhang, Hongyu Cui, Haoming Hu, Xiaokai Yin, Huanqiu Xu

“…It must have a high load-bearing capacity and the ability to withstand large impact loads. In this paper, a novel structure with a positive-negative Poisson’s ratio is proposed. …”
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A novel method for the determination of trace sulfonylurea herbicides by introducing a hybrid stationary phase to common capillary by Jing-Hua Yang, Xiao-Mao Zhou, Yu-Ping Zhang, Jun Chen, Hai-Weng Ma

“…In this paper, a novel polymerized fiber doped with metal–organic frameworks (UIO-66(Zr)-NH 2 ) was developed in a capillary by microwave irradiation. …”
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A Coupled Novel Green Element and Embedded Discrete Fracture Model for Simulation of Fluid Flow in Fractured Reservoir by Linsong Cheng, Xulin Du, Renyi Cao, Zhikai Wang, Junjie Shi

“…In the place of adopting the linear flow approximation for original EDFM, the interflows between local triangle matrix grids and fracture elements are derived using the novel GEM, which has higher accuracy than those in previous EDFMs. …”
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A Novel CRYBB2 Stopgain Mutation Causing Congenital Autosomal Dominant Cataract in a Chinese Family by Yu Zhou, Yaru Zhai, Lulin Huang, Bo Gong, Jie Li, Fang Hao, Zhengzheng Wu, Yi Shi, Yin Yang

“…In conclusion, our findings revealed a novel stopgain mutation c.499T<G (p.E167X) in the exon 6 of CRYBB2 which expanded the mutation spectrum of CRYBB2 in Chinese congenital cataract population and illustrated the important role of CRYBB2 in the genetics research of congenital cataract.…”
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Novel anti-inflammatory properties of mannose oligosaccharides in the treatment of inflammatory bowel disease via LGALS3 modulation by Yaqi Du, Yan Fan, Xin Li, Fenqin Chen

“…These results underscore the potential of dietary polysaccharides like GA-MOS as therapeutic agents in managing dysbiosis and inflammatory conditions in the gut, offering a promising approach for enhancing microbial health and overall disease management in IBD. This study provides novel insights into the bioactive properties of MOS and their interactions with gut microbiota, suggesting broader implications for their use in microbiome-centered therapies.…”
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Hepatoprotective Effects of a Novel Trihoney against Nonalcoholic Fatty Liver Disease: A Comparative Study with Atorvastatin by Hamad Abdulsalam Hamad Alfarisi, Muhammad Bin Ibrahim, Zenab B. Hamad Mohamed, Nuraniza Azahari, Asmah Hanim Bt. Hamdan, Che Anuar Che Mohamad

“…The aim of this study was to investigate the hepatoprotective effects of a novel Trihoney against biochemical and histological manifestations of NAFLD in hypercholesterolemic rabbits. …”
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In-Silico Evaluation of Binding Interaction and ADME Properties of Novel Pyrazoline and Pyrimidine Derivatives Targeting Cyclooxygenase-2 Enzyme by Sarmad Abbas Fadhil, Karima Fadhil Ali, Wesen Adel Mehde

“…The results of using this approach are series of products content of pyrazoline and pyrimidine derivatives that had greater potency as anti-inflammatory action and binding in the active location inside the COX-2 protein may potentially serve as a lead for the identification of novel anti-inflammatory medications to decrease the side effects and toxicity that produced from some NSAIDs. …”
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A Novel Mycobacterium cosmeticum-Like Bacterium Isolated from the Ear Swab of a Patient with Otitis Externa by Jeanette W. P. Teo, Janet W. S. Cheng, Roland Jureen, Raymond T. P. Lin

“…We describe the identification and characterization of a novel nontuberculous mycobacterium (NTM), isolated from an ear swab of an adult male patient with chronic otitis externa. …”
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Association Study between Novel CYP26 Polymorphisms and the Risk of Betel Quid-Related Malignant Oral Disorders by Shyh-Jong Wu, Yun-Ju Chen, Tien-Yu Shieh, Chun-Ming Chen, Yen-Yun Wang, Kun-Tsung Lee, Yueh-Ming Lin, Pei-Hsuan Chien, Ping-Ho Chen

“…Our findings suggest that novel CYP26 polymorphisms are associated with an increased risk of malignant oral disorders, particularly among BQ chewers.…”
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RF Field Build-Up inside a Manned Space Vehicle Using Novel Ray-Tracing Algorithm by Balamati Choudhury, Hema Singh, R. M. Jha

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An effective video captioning based on language description using a novel Graylag Deep Kookaburra Reinforcement Learning by M. Gowri Shankar, D. Surendran

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Development of a rapid detection technology system for noxious plants based on a novel isothermal amplification technique by Ting Zhang, Ting Zhang, Han Xu, Mengdi Liu, Wei Zhang

“…This paper explores for the first time the development and application of a rapid detection technology for noxious plants based on a novel isothermal amplification technique. We targeted the seeds, leaves, and grain impurities of four major noxious weeds: Amaranthus palmeri, the A.tuberculatus complex, Rhaponticum repens, and Euphrosyne xanthiifolia, we designed and screened primers and probes suitable for this isothermal amplification method, determined their limit of detection, optimized the genomic DNA extraction methods, and verified the method. …”
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ARV1 p.Gln62Ter, a novel mutation linked to developmental and epileptic encephalopathy-38 by Mostafa Neissi, Ayoob Radhi Al-Zaalan, Misagh Mohammadi-Asl, Mojdeh Roghani, Javad Mohammadi-Asl, Kamele Jorfi

“…In this case report, we performed whole exome sequencing in an individual diagnosed with developmental and epileptic encephalopathy-38 in an Iranian family, revealing a novel homozygous mutation in the ARV1 gene (c.184C > T [p.Gln62Ter] in exon 2, NM_022786.3). …”
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