A novel DLG4 variant causes DLG4-related synaptopathy with intellectual regression by Sachi Tokunaga, Hideki Shimomura, Naoko Taniguchi, Kumiko Yanagi, Tadashi Kaname, Nobuhiko Okamoto, Yasuhiro Takeshima

“…Abstract DLG4-related synaptopathy is a neurodevelopmental disorder caused by a DLG4 variant. We identified a novel de novo heterozygous frameshift variant, NM_001321075.3(DLG4):c.554_563del, in a Japanese girl. …”
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A Novel Recommendation Algorithm Integrates Resource Allocation and Resource Transfer in Weighted Bipartite Network by Qiang Sun, Leilei Shi, Lu Liu, Zixuan Han, Liang Jiang, Yan Wu, Yeling Zhao

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Identification and validation of a novel autoantibody biomarker panel for differential diagnosis of pancreatic ductal adenocarcinoma by Metoboroghene O. Mowoe, Metoboroghene O. Mowoe, Hisham Allam, Joshua Nqada, Marc Bernon, Karan Gandhi, Sean Burmeister, Urda Kotze, Miriam Kahn, Christo Kloppers, Suba Dharshanan, Zafirah Azween, Pamela Maimela, Paul Townsend, Eduard Jonas, Jonathan M. Blackburn, Jonathan M. Blackburn

“…Subsequently, the specificity of the 11-biomarker panel was validated against other cancers (PDAC vs PC: AUC = 70·3%; PDAC vs CRC: AUC = 84·3%; PDAC vs PRC: AUC = 80·2%) and healthy controls (PDAC vs HC: AUC = 80·9%), confirming that this novel AAb biomarker panel is able to selectively detect PDAC amongst other confounding diseases.ConclusionThis AAb panel may therefore have the potential to form the basis of a novel diagnostic test for PDAC.…”
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Reduction of Image Artifacts in Mice by Bladder Flushing with a Novel Double-Lumen Urethral Catheter by Chad R. Haney, Adrian D. Parasca, Kazuhiro Ichikawa, Benjamin B. Williams, Martyna Elas, Charles A. Pelizzari, Howard J. Halpern

“…To minimize bladder accumulation on mouse images, we developed a novel, minimally invasive, MRI/EPRI-friendly procedure for flushing a female mouse bladder. …”
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A novel arc detection and identification method in pantograph-catenary system based on deep learning by Yue Yan, Hu Liu, Linfeng Gan, Runtong Zhu

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Environmental Supply Chain Performance Mapping of an Enterprise by Exploring a Novel Vague-Intellectual Approach by Juan Wang, M. Prabhu, Abatihun Alehegn Sewagegn, Anoop Kumar Sahu

“…Furthermore, the authors developed GTFN set-based novel fuzzy performance index (NFPI) approach (by combining the crisp as well as fuzzy percentage rule over FPI) to compute the performance in %. …”
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A Novel Approach to Numerical Modeling of Metabolic System: Investigation of Chaotic Behavior in Diabetes Mellitus by Payam Sadeghi Shabestari, Karthikeyan Rajagopal, Bahareh Safarbali, Sajad Jafari, Prakash Duraisamy

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MFEMDroid: A Novel Malware Detection Framework Using Combined Multitype Features and Ensemble Modeling by Wei Gu, Hongyan Xing, Tianhao Hou

“…In this study, to solve the abovementioned problems, we propose a novel malware detection framework MFEMDroid, which combines multitype features analysis and ensemble modeling. …”
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Dexmedetomidine Use in the Setting of Cocaine-Induced Hypertensive Emergency and Aortic Dissection: A Novel Indication by Fahad Javed, Alexandre Miguel Benjo, Kiran Reddy, Muhammad Shoaib Akram, Shahzeb Afsar Khan, Manpreet Singh Sabharwal, Girish Nadkarni, Emad F. Aziz, Eyal Herzog

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A Novel Dual-Shorting Point PIFA (GSM850 to IMT-A) for Mobile Handsets by Pengcheng Li, Jin Pan, Deqiang Yang, Pingzai Nie

“…A novel planar inverted-F antenna (PIFA) with dual-shorting points is proposed for multiband mobile handsets. …”
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A novel method for encoding and decoding based on enhanced parity-check-concatenated polar codes by Yan WANG, Shunlan LIU, Zhenzhen XI, Jianrong BAO

“…While the length of polar codes is short, its performance is not good enough. A novel method for encoding and decoding based on enhanced parity-check-concatenated polar codes was proposed. …”
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Novel Distributed PZT Active Vibration Control Based on Characteristic Model for the Space Frame Structure by Hua Zhong, Yong Wang, Hanzheng Ran, Qing Wang, Changxing Shao

“…A novel distributed PZT control strategy based on characteristic model is presented for space frame structure in this paper. …”
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Characterization of the Prediabetic State in a Novel Rat Model of Type 2 Diabetes, the ZFDM Rat by Ghupurjan Gheni, Norihide Yokoi, Masayuki Beppu, Takuro Yamaguchi, Shihomi Hidaka, Ayako Kawabata, Yoshikazu Hoshino, Masayuki Hoshino, Susumu Seino

“…We recently established a novel animal model of obese type 2 diabetes (T2D), the Zucker fatty diabetes mellitus (ZFDM) rat strain harboring the fatty mutation (fa) in the leptin receptor gene. …”
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Estimation of the Student Employment in the Aviation Industry Based on Novel Fractional Error Accumulation Grey Model by Yali Zhang, Xiaojiang Yang, Wei Cui

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Identification of novel RIPK4 variants in a Chinese patient with Arthrogryposis Multiplex Congenita (AMC) by Yi-Lei Lu, Meng-wei Liu, Jie-Yuan Jin, Ding Pan

“…Results We identified two novel RIPK4 variants (c.1354G > A, p.E452K; c.1558A > T, p.T520S). …”
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Positive Expression of IGFBP2 as a Novel Prognostic Biomarker for Patients with Lower-Grade Gliomas by Yanguo Li, Jiawei Fan, Zhuo Shen, Jun Zhang, Xuemei Yin, Fang Han, Wenfei Li

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Appraising the Pile Settlement Rates by Support Vector Regression Optimized Using the Novel Optimization Algorithms by Argyros Maris

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Analysis of the Complete Genome Sequence of a Novel, Pseudorabies Virus Strain Isolated in Southeast Europe by Zsolt Csabai, Dóra Tombácz, Zoltán Deim, Michael Snyder, Zsolt Boldogkői

“…Results. In this study, a novel PRV strain was isolated and characterized. …”
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Repositioning of the Severe Prolapsed Silicone Tubes after Bicanalicular Nasal Intubation: A Novel Technique by Jinjing He, Jingwen Gong, Qingqing Zheng, Jin Jiang

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In vitro and ex vivo models of the oral mucosa as platforms for the validation of novel drug delivery systems by Robyn A Macartney, Abijit Das, Atina G Imaniyyah, Annabelle TR Fricker, Andrew M Smith, Stefano Fedele, Ipsita Roy, Hae-Won Kim, Dongjoon Lee, Jonathan C Knowles

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