Rapid Determination of 26 Pyrrolizidine Alkaloids in Milk Power and Liquid Milk by Solid Phase Extraction Combined with Ultra-high Performance Liquid Chromatography-Tandem Mass Spe... by CHEN Yankai

“…The samples were extracted with 5% trichloroacetic acid solution, cleaned up on a polymer cation exchange-solid phase extraction (PCX-SPE) column, separated on an ACQUITY HSS T3 column with gradient elution using a mobile phase consisting of methanol and 0.1% formic acid in water, detected using an electrospray ionization (ESI) in the positive ion mode with multiple reaction monitoring (MRM), and finally quantified by the external standard method. The method validation was performed under optimal conditions. …”
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Post Mortem Paliperidone Blood Concentrations Following Long-Acting Injectable Treatments by Pietro Zuccarello, Giulia Carnazza, Antonino Petralia, Nunziata Barbera

“…The aims of the present study were (a) to develop an analytical method to detect and quantify paliperidone in whole blood using only a small sample volume (10 µL) and (b) to summarize data on post-mortem blood analysis obtained from authentic autopsy cases. <b>Methods:</b> Method validation was carried out on 10 µL of whole blood, extracted by LLE and analyzed by LC-MS. …”
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