Extensive Thrombosis of the Inferior Vena Cava and Left Renal Vein in a Neonate

Antenatal renal vein thrombosis is a rarely described diagnostic finding, with variable consequences on kidney function. We present the case of an affected fetus, born at 35-week gestation, with intrauterine oligohydramnios and two small kidneys. A renal ultrasound carried out after birth confirmed...

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Main Authors: Moez Kdous, Oussema Khlifi, Marwene Brahem, Mohamed Khrouf, Sarah Amari, Monia Ferchiou, Fethi Zhioua
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Case Reports in Obstetrics and Gynecology
Online Access:http://dx.doi.org/10.1155/2015/569797
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author Moez Kdous
Oussema Khlifi
Marwene Brahem
Mohamed Khrouf
Sarah Amari
Monia Ferchiou
Fethi Zhioua
author_facet Moez Kdous
Oussema Khlifi
Marwene Brahem
Mohamed Khrouf
Sarah Amari
Monia Ferchiou
Fethi Zhioua
author_sort Moez Kdous
collection DOAJ
description Antenatal renal vein thrombosis is a rarely described diagnostic finding, with variable consequences on kidney function. We present the case of an affected fetus, born at 35-week gestation, with intrauterine oligohydramnios and two small kidneys. A renal ultrasound carried out after birth confirmed the presence of prenatal abnormalities. Renal vein thrombosis was not diagnosed at the time. The baby died 20 days later of kidney failure, metabolic acidosis, and polypnea with severe hypotrophy. Autopsy revealed atrophied kidneys and adrenal glands. The vena cava had thrombosis occupying most of its length. The right renal vein was normal, while the left renal vein was threadlike and not permeable. Histologically, there was necrosis of the left adrenal gland with asymmetrical bilateral renal impairment and signs of ischemic and hemorrhagic lesions. A review of thrombophilia was carried out and a heterozygous mutation in Factor V was found in both the mother and the child.
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publishDate 2015-01-01
publisher Wiley
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series Case Reports in Obstetrics and Gynecology
spelling doaj-art-fffe53b7ffe04907837f5f95666d0a972025-02-03T01:09:48ZengWileyCase Reports in Obstetrics and Gynecology2090-66842090-66922015-01-01201510.1155/2015/569797569797Extensive Thrombosis of the Inferior Vena Cava and Left Renal Vein in a NeonateMoez Kdous0Oussema Khlifi1Marwene Brahem2Mohamed Khrouf3Sarah Amari4Monia Ferchiou5Fethi Zhioua6Department of Obstetrics and Gynecologic Surgery, Aziza Othmana Hospital, Kasbah, 1008 Tunis, TunisiaDepartment of Obstetrics and Gynecologic Surgery, Aziza Othmana Hospital, Kasbah, 1008 Tunis, TunisiaDepartment of Obstetrics and Gynecologic Surgery, Aziza Othmana Hospital, Kasbah, 1008 Tunis, TunisiaDepartment of Obstetrics and Gynecologic Surgery, Aziza Othmana Hospital, Kasbah, 1008 Tunis, TunisiaDepartment of Obstetrics and Gynecologic Surgery, Aziza Othmana Hospital, Kasbah, 1008 Tunis, TunisiaDepartment of Obstetrics and Gynecologic Surgery, Aziza Othmana Hospital, Kasbah, 1008 Tunis, TunisiaDepartment of Obstetrics and Gynecologic Surgery, Aziza Othmana Hospital, Kasbah, 1008 Tunis, TunisiaAntenatal renal vein thrombosis is a rarely described diagnostic finding, with variable consequences on kidney function. We present the case of an affected fetus, born at 35-week gestation, with intrauterine oligohydramnios and two small kidneys. A renal ultrasound carried out after birth confirmed the presence of prenatal abnormalities. Renal vein thrombosis was not diagnosed at the time. The baby died 20 days later of kidney failure, metabolic acidosis, and polypnea with severe hypotrophy. Autopsy revealed atrophied kidneys and adrenal glands. The vena cava had thrombosis occupying most of its length. The right renal vein was normal, while the left renal vein was threadlike and not permeable. Histologically, there was necrosis of the left adrenal gland with asymmetrical bilateral renal impairment and signs of ischemic and hemorrhagic lesions. A review of thrombophilia was carried out and a heterozygous mutation in Factor V was found in both the mother and the child.http://dx.doi.org/10.1155/2015/569797
spellingShingle Moez Kdous
Oussema Khlifi
Marwene Brahem
Mohamed Khrouf
Sarah Amari
Monia Ferchiou
Fethi Zhioua
Extensive Thrombosis of the Inferior Vena Cava and Left Renal Vein in a Neonate
Case Reports in Obstetrics and Gynecology
title Extensive Thrombosis of the Inferior Vena Cava and Left Renal Vein in a Neonate
title_full Extensive Thrombosis of the Inferior Vena Cava and Left Renal Vein in a Neonate
title_fullStr Extensive Thrombosis of the Inferior Vena Cava and Left Renal Vein in a Neonate
title_full_unstemmed Extensive Thrombosis of the Inferior Vena Cava and Left Renal Vein in a Neonate
title_short Extensive Thrombosis of the Inferior Vena Cava and Left Renal Vein in a Neonate
title_sort extensive thrombosis of the inferior vena cava and left renal vein in a neonate
url http://dx.doi.org/10.1155/2015/569797
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