Extensive Thrombosis of the Inferior Vena Cava and Left Renal Vein in a Neonate
Antenatal renal vein thrombosis is a rarely described diagnostic finding, with variable consequences on kidney function. We present the case of an affected fetus, born at 35-week gestation, with intrauterine oligohydramnios and two small kidneys. A renal ultrasound carried out after birth confirmed...
Saved in:
Main Authors: | , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Wiley
2015-01-01
|
Series: | Case Reports in Obstetrics and Gynecology |
Online Access: | http://dx.doi.org/10.1155/2015/569797 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
_version_ | 1832565000402632704 |
---|---|
author | Moez Kdous Oussema Khlifi Marwene Brahem Mohamed Khrouf Sarah Amari Monia Ferchiou Fethi Zhioua |
author_facet | Moez Kdous Oussema Khlifi Marwene Brahem Mohamed Khrouf Sarah Amari Monia Ferchiou Fethi Zhioua |
author_sort | Moez Kdous |
collection | DOAJ |
description | Antenatal renal vein thrombosis is a rarely described diagnostic finding, with variable consequences on kidney function. We present the case of an affected fetus, born at 35-week gestation, with intrauterine oligohydramnios and two small kidneys. A renal ultrasound carried out after birth confirmed the presence of prenatal abnormalities. Renal vein thrombosis was not diagnosed at the time. The baby died 20 days later of kidney failure, metabolic acidosis, and polypnea with severe hypotrophy. Autopsy revealed atrophied kidneys and adrenal glands. The vena cava had thrombosis occupying most of its length. The right renal vein was normal, while the left renal vein was threadlike and not permeable. Histologically, there was necrosis of the left adrenal gland with asymmetrical bilateral renal impairment and signs of ischemic and hemorrhagic lesions. A review of thrombophilia was carried out and a heterozygous mutation in Factor V was found in both the mother and the child. |
format | Article |
id | doaj-art-fffe53b7ffe04907837f5f95666d0a97 |
institution | Kabale University |
issn | 2090-6684 2090-6692 |
language | English |
publishDate | 2015-01-01 |
publisher | Wiley |
record_format | Article |
series | Case Reports in Obstetrics and Gynecology |
spelling | doaj-art-fffe53b7ffe04907837f5f95666d0a972025-02-03T01:09:48ZengWileyCase Reports in Obstetrics and Gynecology2090-66842090-66922015-01-01201510.1155/2015/569797569797Extensive Thrombosis of the Inferior Vena Cava and Left Renal Vein in a NeonateMoez Kdous0Oussema Khlifi1Marwene Brahem2Mohamed Khrouf3Sarah Amari4Monia Ferchiou5Fethi Zhioua6Department of Obstetrics and Gynecologic Surgery, Aziza Othmana Hospital, Kasbah, 1008 Tunis, TunisiaDepartment of Obstetrics and Gynecologic Surgery, Aziza Othmana Hospital, Kasbah, 1008 Tunis, TunisiaDepartment of Obstetrics and Gynecologic Surgery, Aziza Othmana Hospital, Kasbah, 1008 Tunis, TunisiaDepartment of Obstetrics and Gynecologic Surgery, Aziza Othmana Hospital, Kasbah, 1008 Tunis, TunisiaDepartment of Obstetrics and Gynecologic Surgery, Aziza Othmana Hospital, Kasbah, 1008 Tunis, TunisiaDepartment of Obstetrics and Gynecologic Surgery, Aziza Othmana Hospital, Kasbah, 1008 Tunis, TunisiaDepartment of Obstetrics and Gynecologic Surgery, Aziza Othmana Hospital, Kasbah, 1008 Tunis, TunisiaAntenatal renal vein thrombosis is a rarely described diagnostic finding, with variable consequences on kidney function. We present the case of an affected fetus, born at 35-week gestation, with intrauterine oligohydramnios and two small kidneys. A renal ultrasound carried out after birth confirmed the presence of prenatal abnormalities. Renal vein thrombosis was not diagnosed at the time. The baby died 20 days later of kidney failure, metabolic acidosis, and polypnea with severe hypotrophy. Autopsy revealed atrophied kidneys and adrenal glands. The vena cava had thrombosis occupying most of its length. The right renal vein was normal, while the left renal vein was threadlike and not permeable. Histologically, there was necrosis of the left adrenal gland with asymmetrical bilateral renal impairment and signs of ischemic and hemorrhagic lesions. A review of thrombophilia was carried out and a heterozygous mutation in Factor V was found in both the mother and the child.http://dx.doi.org/10.1155/2015/569797 |
spellingShingle | Moez Kdous Oussema Khlifi Marwene Brahem Mohamed Khrouf Sarah Amari Monia Ferchiou Fethi Zhioua Extensive Thrombosis of the Inferior Vena Cava and Left Renal Vein in a Neonate Case Reports in Obstetrics and Gynecology |
title | Extensive Thrombosis of the Inferior Vena Cava and Left Renal Vein in a Neonate |
title_full | Extensive Thrombosis of the Inferior Vena Cava and Left Renal Vein in a Neonate |
title_fullStr | Extensive Thrombosis of the Inferior Vena Cava and Left Renal Vein in a Neonate |
title_full_unstemmed | Extensive Thrombosis of the Inferior Vena Cava and Left Renal Vein in a Neonate |
title_short | Extensive Thrombosis of the Inferior Vena Cava and Left Renal Vein in a Neonate |
title_sort | extensive thrombosis of the inferior vena cava and left renal vein in a neonate |
url | http://dx.doi.org/10.1155/2015/569797 |
work_keys_str_mv | AT moezkdous extensivethrombosisoftheinferiorvenacavaandleftrenalveininaneonate AT oussemakhlifi extensivethrombosisoftheinferiorvenacavaandleftrenalveininaneonate AT marwenebrahem extensivethrombosisoftheinferiorvenacavaandleftrenalveininaneonate AT mohamedkhrouf extensivethrombosisoftheinferiorvenacavaandleftrenalveininaneonate AT sarahamari extensivethrombosisoftheinferiorvenacavaandleftrenalveininaneonate AT moniaferchiou extensivethrombosisoftheinferiorvenacavaandleftrenalveininaneonate AT fethizhioua extensivethrombosisoftheinferiorvenacavaandleftrenalveininaneonate |