Nanoparticle-Based Therapies for Management of Subarachnoid Hemorrhage, Neurotrauma, and Stroke
Neurotrauma, stroke, and subarachnoid hemorrhage (SAH) are symptomatically diverse and etiologically complex central nervous system pathologies. Despite numerous therapeutic modalities that are available to minimize neurologic damage and secondary injury, the prognosis can still be dismal and unpred...
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| Format: | Article |
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MDPI AG
2024-12-01
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| Series: | Biomedicines |
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| Online Access: | https://www.mdpi.com/2227-9059/13/1/16 |
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| author | Grace Hey Ilyas Mehkri Yusuf Mehkri Hasan Maqbool Mubariz Tahirkheli Samuel Woodford Brandon Lucke-Wold |
| author_facet | Grace Hey Ilyas Mehkri Yusuf Mehkri Hasan Maqbool Mubariz Tahirkheli Samuel Woodford Brandon Lucke-Wold |
| author_sort | Grace Hey |
| collection | DOAJ |
| description | Neurotrauma, stroke, and subarachnoid hemorrhage (SAH) are symptomatically diverse and etiologically complex central nervous system pathologies. Despite numerous therapeutic modalities that are available to minimize neurologic damage and secondary injury, the prognosis can still be dismal and unpredictable. Nanoparticle (NP) technology allows for deliberate, modular, and minimally invasive drug delivery. This literature review encompasses pertinent information on the impact and versatility of nanoparticle therapeutics when treating neurotrauma, stroke, and SAH. Currently, notable treatments such as Perfluorooctyl-Bromide (PFOB), PLGA nanoparticles, and ischemic relief-based NPs are promising new techniques for the management of these complex pathologies. |
| format | Article |
| id | doaj-art-ffe419486036491ca863c90f593e9477 |
| institution | Kabale University |
| issn | 2227-9059 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biomedicines |
| spelling | doaj-art-ffe419486036491ca863c90f593e94772025-01-24T13:23:43ZengMDPI AGBiomedicines2227-90592024-12-011311610.3390/biomedicines13010016Nanoparticle-Based Therapies for Management of Subarachnoid Hemorrhage, Neurotrauma, and StrokeGrace Hey0Ilyas Mehkri1Yusuf Mehkri2Hasan Maqbool3Mubariz Tahirkheli4Samuel Woodford5Brandon Lucke-Wold6College of Medicine, University of Florida, Gainesville, FL 32610, USACollege of Medicine, University of Florida, Gainesville, FL 32610, USACollege of Medicine, University of Florida, Gainesville, FL 32610, USACollege of Medicine, University of Florida, Gainesville, FL 32610, USACollege of Medicine, University of Florida, Gainesville, FL 32610, USACollege of Medicine, University of Florida, Gainesville, FL 32610, USALillian S. Wells Department of Neurosurgery, College of Medicine, University of Florida, 1600 SW Archer Road, Gainesville, FL 32610, USANeurotrauma, stroke, and subarachnoid hemorrhage (SAH) are symptomatically diverse and etiologically complex central nervous system pathologies. Despite numerous therapeutic modalities that are available to minimize neurologic damage and secondary injury, the prognosis can still be dismal and unpredictable. Nanoparticle (NP) technology allows for deliberate, modular, and minimally invasive drug delivery. This literature review encompasses pertinent information on the impact and versatility of nanoparticle therapeutics when treating neurotrauma, stroke, and SAH. Currently, notable treatments such as Perfluorooctyl-Bromide (PFOB), PLGA nanoparticles, and ischemic relief-based NPs are promising new techniques for the management of these complex pathologies.https://www.mdpi.com/2227-9059/13/1/16nanoparticleneurotraumastrokesubarachnoid hemorrhage |
| spellingShingle | Grace Hey Ilyas Mehkri Yusuf Mehkri Hasan Maqbool Mubariz Tahirkheli Samuel Woodford Brandon Lucke-Wold Nanoparticle-Based Therapies for Management of Subarachnoid Hemorrhage, Neurotrauma, and Stroke Biomedicines nanoparticle neurotrauma stroke subarachnoid hemorrhage |
| title | Nanoparticle-Based Therapies for Management of Subarachnoid Hemorrhage, Neurotrauma, and Stroke |
| title_full | Nanoparticle-Based Therapies for Management of Subarachnoid Hemorrhage, Neurotrauma, and Stroke |
| title_fullStr | Nanoparticle-Based Therapies for Management of Subarachnoid Hemorrhage, Neurotrauma, and Stroke |
| title_full_unstemmed | Nanoparticle-Based Therapies for Management of Subarachnoid Hemorrhage, Neurotrauma, and Stroke |
| title_short | Nanoparticle-Based Therapies for Management of Subarachnoid Hemorrhage, Neurotrauma, and Stroke |
| title_sort | nanoparticle based therapies for management of subarachnoid hemorrhage neurotrauma and stroke |
| topic | nanoparticle neurotrauma stroke subarachnoid hemorrhage |
| url | https://www.mdpi.com/2227-9059/13/1/16 |
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