Efficacy, Safety, and Cost-Effectiveness Analysis of Ceftazidime-Avibactam versus Polymyxin B in the Treatment of Carbapenem-Resistant Enterobacteriaceae Infections: A Target Trial Emulation

Efficacy, Safety, and Cost-Effectiveness Analysis of Ceftazidime-Avibactam versus Polymyxin B in the Treatment of Carbapenem-Resistant Enterobacteriaceae Infections: A Target Trial Emulation

Abstract Introduction Treatment options for carbapenem-resistant Enterobacteriaceae (CRE) infections are limited, with polymyxin B (PMB) and ceftazidime-avibactam (CZA) being among the available choices. However, research on these options is scarce and significantly heterogeneous. This study aims to...

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Bibliographic Details
Main Authors: Na Hu, Fengjiao Xiao, Yechao Chen, Qiaoling Gu, Pei Liang, Yin Xu, Jinchun Liu, Yunxing Liu, Yi-chen Li, Yinqiu Xu, Mengyin Liu, Dayu Chen, Haixia Zhang
Format: Article
Language:English
Published: Adis, Springer Healthcare 2025-05-01
Series:Infectious Diseases and Therapy
Subjects:
Target trial emulation
Ceftazidime-avibactam
Polymyxin B
Carbapenem-resistant Enterobacteriaceae
Cost-effectiveness
Online Access:https://doi.org/10.1007/s40121-025-01164-9
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