Primary Dural Spinal Lymphoma Presentation of a Rare Spinal Tumor Case
Background. Primary spinal dural lymphomas (PSDL) are tumors with characteristic histopathology of a lymphoma, which are completely in the spinal epidural space without any other systemic involvement. Extranodal primary lymphoma involving nervous system prefers thalamus/basal ganglia, periventricula...
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Case Reports in Surgery |
| Online Access: | http://dx.doi.org/10.1155/2015/639253 |
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| author | Dilber Ayçiçek Çeçen Necati Tatarlı Hikmet Turan Süslü Selçuk Özdoğan Nagehan Özdemir Barışık |
| author_facet | Dilber Ayçiçek Çeçen Necati Tatarlı Hikmet Turan Süslü Selçuk Özdoğan Nagehan Özdemir Barışık |
| author_sort | Dilber Ayçiçek Çeçen |
| collection | DOAJ |
| description | Background. Primary spinal dural lymphomas (PSDL) are tumors with characteristic histopathology of a lymphoma, which are completely in the spinal epidural space without any other systemic involvement. Extranodal primary lymphoma involving nervous system prefers thalamus/basal ganglia, periventricular region, cerebellum, eyes, meninges/dura, and cranial nerves or spinal cord. Rare spinal localization with acute spinal cord compression is worth attention. Case Presentation. A 48-year-old male presented with a several-month-long history of upper back pain. Lately, he had numbness and weakness at both lower extremities and was unable to walk for one week. A spinal MRI showed a thoracic lesion with cord compression at T2–T4 levels. The patient underwent surgical decompression, with his final histopathology showing diffuse large B-cell lymphoma. Systemic work-up was negative for nodal disease. Following surgery, he received radiotherapy combined with chemotherapy. He experienced a good outcome after four years. Conclusion. The upper thoracic cord is a rare location for primary spinal lesions/metastases, both of which prefer the lower thoracic and upper lumbar regions. In cases of progressive paraparesis, there should be immediate surgical intervention in the case of denovo disease, followed by combined radiotherapy and chemotherapy procedures. |
| format | Article |
| id | doaj-art-ffe155a18c634a878fd582d36457c7da |
| institution | Kabale University |
| issn | 2090-6900 2090-6919 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Surgery |
| spelling | doaj-art-ffe155a18c634a878fd582d36457c7da2025-02-03T01:11:12ZengWileyCase Reports in Surgery2090-69002090-69192015-01-01201510.1155/2015/639253639253Primary Dural Spinal Lymphoma Presentation of a Rare Spinal Tumor CaseDilber Ayçiçek Çeçen0Necati Tatarlı1Hikmet Turan Süslü2Selçuk Özdoğan3Nagehan Özdemir Barışık4Department of Neurosurgery, Dr. Lütfi Kırdar Kartal Education and Research Hospital, 34852 Istanbul, TurkeyDepartment of Neurosurgery, Dr. Lütfi Kırdar Kartal Education and Research Hospital, 34852 Istanbul, TurkeyDepartment of Neurosurgery, Dr. Lütfi Kırdar Kartal Education and Research Hospital, 34852 Istanbul, TurkeyDepartment of Neurosurgery, Dr. Lütfi Kırdar Kartal Education and Research Hospital, 34852 Istanbul, TurkeyDepartment of Pathology, Dr. Lütfi Kırdar Kartal Education and Research Hospital, 34852 Istanbul, TurkeyBackground. Primary spinal dural lymphomas (PSDL) are tumors with characteristic histopathology of a lymphoma, which are completely in the spinal epidural space without any other systemic involvement. Extranodal primary lymphoma involving nervous system prefers thalamus/basal ganglia, periventricular region, cerebellum, eyes, meninges/dura, and cranial nerves or spinal cord. Rare spinal localization with acute spinal cord compression is worth attention. Case Presentation. A 48-year-old male presented with a several-month-long history of upper back pain. Lately, he had numbness and weakness at both lower extremities and was unable to walk for one week. A spinal MRI showed a thoracic lesion with cord compression at T2–T4 levels. The patient underwent surgical decompression, with his final histopathology showing diffuse large B-cell lymphoma. Systemic work-up was negative for nodal disease. Following surgery, he received radiotherapy combined with chemotherapy. He experienced a good outcome after four years. Conclusion. The upper thoracic cord is a rare location for primary spinal lesions/metastases, both of which prefer the lower thoracic and upper lumbar regions. In cases of progressive paraparesis, there should be immediate surgical intervention in the case of denovo disease, followed by combined radiotherapy and chemotherapy procedures.http://dx.doi.org/10.1155/2015/639253 |
| spellingShingle | Dilber Ayçiçek Çeçen Necati Tatarlı Hikmet Turan Süslü Selçuk Özdoğan Nagehan Özdemir Barışık Primary Dural Spinal Lymphoma Presentation of a Rare Spinal Tumor Case Case Reports in Surgery |
| title | Primary Dural Spinal Lymphoma Presentation of a Rare Spinal Tumor Case |
| title_full | Primary Dural Spinal Lymphoma Presentation of a Rare Spinal Tumor Case |
| title_fullStr | Primary Dural Spinal Lymphoma Presentation of a Rare Spinal Tumor Case |
| title_full_unstemmed | Primary Dural Spinal Lymphoma Presentation of a Rare Spinal Tumor Case |
| title_short | Primary Dural Spinal Lymphoma Presentation of a Rare Spinal Tumor Case |
| title_sort | primary dural spinal lymphoma presentation of a rare spinal tumor case |
| url | http://dx.doi.org/10.1155/2015/639253 |
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