A Study to Determine the Association between Monocyte to HDL Cholesterol Ratio, Neutrophil to Lymphocyte Ratio, Red Blood Cell Distribution Width (RDW), and Diabetic Retinopathy in a Tertiary Care Hospital in Eastern India
Background: Diabetic retinopathy is an important microvascular complication of diabetes mellitus (DM) leading to visual impairment. Inflammation of retinal vasculature plays a pivotal role in its pathogenesis. Our aim of this study is to determine the association between diabetic retinopathy and mon...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Jaypee Brothers Medical Publisher
2025-06-01
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| Series: | Bengal Physician Journal |
| Subjects: | |
| Online Access: | https://www.apibpj.com/doi/BPJ/pdf/10.5005/jp-journals-10070-8060 |
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| Summary: | Background: Diabetic retinopathy is an important microvascular complication of diabetes mellitus (DM) leading to visual impairment. Inflammation of retinal vasculature plays a pivotal role in its pathogenesis. Our aim of this study is to determine the association between diabetic retinopathy and monocyte to high-density lipoprotein (HDL) cholesterol ratio (MHR), neutrophil to lymphocyte ratio (NLR), and red blood cell distribution width (RDW).
Methods: One hundred and fifty adult type 2 DM were included based on inclusion and exclusion criteria—50 diabetics without retinopathy, 50 with proliferative retinopathy, and 50 with non-proliferative retinopathy. All patients underwent routine blood investigations and the data was collected and analyzed.
Results: The mean NLR, MHR, and RDW were higher in diabetic patients with retinopathy than diabetics without it and it was higher among proliferative diabetic retinopathy than non-proliferative retinopathy subjects. A significant association was found in all cases with a <i>p</i>-value < 0.05.
Conclusion: NLR, MHR, and RDW can be useful predicting tools, especially in peripheral setups. |
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| ISSN: | 2582-1202 |