Advanced point-of-care biomarker testing for the diagnosis of cardiovascular diseases

Cardiovascular disease (CVD) stands as the primary cause of global mortality, necessitating early diagnosis for mitigating death rates and improving quality of life. Conventional CVD diagnostic techniques necessitate the use of bulky hospital instruments for electrocardiogram recording and immunoass...

Full description

Saved in:
Bibliographic Details
Main Authors: Wenjun Ming, Yidan Zhu, Wenjun Jiang, Jing Zhang, Jinxia Liu, Li Wu, Yuling Qin
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Sensing and Bio-Sensing Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2214180425000133
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832583875689185280
author Wenjun Ming
Yidan Zhu
Wenjun Jiang
Jing Zhang
Jinxia Liu
Li Wu
Yuling Qin
author_facet Wenjun Ming
Yidan Zhu
Wenjun Jiang
Jing Zhang
Jinxia Liu
Li Wu
Yuling Qin
author_sort Wenjun Ming
collection DOAJ
description Cardiovascular disease (CVD) stands as the primary cause of global mortality, necessitating early diagnosis for mitigating death rates and improving quality of life. Conventional CVD diagnostic techniques necessitate the use of bulky hospital instruments for electrocardiogram recording and immunoassay, resulting in time-consuming and inconvenient limitations. Point-of-care testing (POCT) presents unique benefits compared to traditional central laboratory (CLT) methods, such as accelerated turnaround times for results, enhanced portability, and ease of use, which are especially beneficial in resource-constrained healthcare environments. As a result, POCT is increasingly recognized as an innovative diagnostic strategy for the management of CVD, achieving significant standing across a variety of healthcare scenarios. The present review offers a comprehensive overview of the prevailing categories of cardiovascular diseases and emphasizes the diagnostic application of cardiac biomarkers detected through blood tests. The focus of this study is specifically on POCT devices used for the detection of biomarkers related to cardiovascular disease. Additionally, their performance will be compared and evaluated against traditional CLT methods and commercially available equipment. With the growing implementation of hierarchical medical policies and increasing demand for health management services, the market for POCT cardiac biomarkers testing is expected to expand further as a crucial development direction within the field of medicine.
format Article
id doaj-art-ffc2deff14e446119b4412af08794881
institution Kabale University
issn 2214-1804
language English
publishDate 2025-02-01
publisher Elsevier
record_format Article
series Sensing and Bio-Sensing Research
spelling doaj-art-ffc2deff14e446119b4412af087948812025-01-28T04:14:36ZengElsevierSensing and Bio-Sensing Research2214-18042025-02-0147100747Advanced point-of-care biomarker testing for the diagnosis of cardiovascular diseasesWenjun Ming0Yidan Zhu1Wenjun Jiang2Jing Zhang3Jinxia Liu4Li Wu5Yuling Qin6School of Public Health, Nantong Key Laboratory of Public Health and Medical Analysis, Nantong University, Nantong 226019, PR ChinaSchool of Public Health, Nantong Key Laboratory of Public Health and Medical Analysis, Nantong University, Nantong 226019, PR China; Medical School, Nantong University, Nantong, Jiangsu 226001, PR ChinaSchool of Public Health, Nantong Key Laboratory of Public Health and Medical Analysis, Nantong University, Nantong 226019, PR ChinaSchool of Public Health, Nantong Key Laboratory of Public Health and Medical Analysis, Nantong University, Nantong 226019, PR ChinaSchool of Public Health, Nantong Key Laboratory of Public Health and Medical Analysis, Nantong University, Nantong 226019, PR China; Corresponding authors.School of Life Science, Nantong University, Nantong, Jiangsu 226019, PR China; Corresponding authors.School of Public Health, Nantong Key Laboratory of Public Health and Medical Analysis, Nantong University, Nantong 226019, PR China; Corresponding authors.Cardiovascular disease (CVD) stands as the primary cause of global mortality, necessitating early diagnosis for mitigating death rates and improving quality of life. Conventional CVD diagnostic techniques necessitate the use of bulky hospital instruments for electrocardiogram recording and immunoassay, resulting in time-consuming and inconvenient limitations. Point-of-care testing (POCT) presents unique benefits compared to traditional central laboratory (CLT) methods, such as accelerated turnaround times for results, enhanced portability, and ease of use, which are especially beneficial in resource-constrained healthcare environments. As a result, POCT is increasingly recognized as an innovative diagnostic strategy for the management of CVD, achieving significant standing across a variety of healthcare scenarios. The present review offers a comprehensive overview of the prevailing categories of cardiovascular diseases and emphasizes the diagnostic application of cardiac biomarkers detected through blood tests. The focus of this study is specifically on POCT devices used for the detection of biomarkers related to cardiovascular disease. Additionally, their performance will be compared and evaluated against traditional CLT methods and commercially available equipment. With the growing implementation of hierarchical medical policies and increasing demand for health management services, the market for POCT cardiac biomarkers testing is expected to expand further as a crucial development direction within the field of medicine.http://www.sciencedirect.com/science/article/pii/S2214180425000133Cardiovascular disease (CVD)Point-of-care testing (POCT)BiosensorsCardiovascular biomarkersCommercial diagnostic devices
spellingShingle Wenjun Ming
Yidan Zhu
Wenjun Jiang
Jing Zhang
Jinxia Liu
Li Wu
Yuling Qin
Advanced point-of-care biomarker testing for the diagnosis of cardiovascular diseases
Sensing and Bio-Sensing Research
Cardiovascular disease (CVD)
Point-of-care testing (POCT)
Biosensors
Cardiovascular biomarkers
Commercial diagnostic devices
title Advanced point-of-care biomarker testing for the diagnosis of cardiovascular diseases
title_full Advanced point-of-care biomarker testing for the diagnosis of cardiovascular diseases
title_fullStr Advanced point-of-care biomarker testing for the diagnosis of cardiovascular diseases
title_full_unstemmed Advanced point-of-care biomarker testing for the diagnosis of cardiovascular diseases
title_short Advanced point-of-care biomarker testing for the diagnosis of cardiovascular diseases
title_sort advanced point of care biomarker testing for the diagnosis of cardiovascular diseases
topic Cardiovascular disease (CVD)
Point-of-care testing (POCT)
Biosensors
Cardiovascular biomarkers
Commercial diagnostic devices
url http://www.sciencedirect.com/science/article/pii/S2214180425000133
work_keys_str_mv AT wenjunming advancedpointofcarebiomarkertestingforthediagnosisofcardiovasculardiseases
AT yidanzhu advancedpointofcarebiomarkertestingforthediagnosisofcardiovasculardiseases
AT wenjunjiang advancedpointofcarebiomarkertestingforthediagnosisofcardiovasculardiseases
AT jingzhang advancedpointofcarebiomarkertestingforthediagnosisofcardiovasculardiseases
AT jinxialiu advancedpointofcarebiomarkertestingforthediagnosisofcardiovasculardiseases
AT liwu advancedpointofcarebiomarkertestingforthediagnosisofcardiovasculardiseases
AT yulingqin advancedpointofcarebiomarkertestingforthediagnosisofcardiovasculardiseases