The inconclusive superiority debate of allogeneic versus autologous MSCs in treating patients with HFrEF: a systematic review and meta-analysis of RCTs

The inconclusive superiority debate of allogeneic versus autologous MSCs in treating patients with HFrEF: a systematic review and meta-analysis of RCTs

Abstract Background Recent randomized controlled trials have consistently demonstrated the safety and potential efficacy of MSC therapy for heart failure patients. This study delves into mesenchymal stem cells’ promising potential, offering a beacon of hope for the future of heart failure treatment...

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Main Authors: Omar T. F. Ahmed, Ziyad Tarek Ahmed, Abdulrahman W. Dairi, Maha Saad Zain Al-Abeden, Mohammed H. Alkahlot, Rana H. Alkahlot, Ghazi I. Al Jowf, Lars M. T. Eijssen, Khawaja Husnain Haider
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Stem Cell Research & Therapy
Subjects:
Autologous
Allogeneic
Heart failure
HFrEF
Mesenchymal stem cells
Mesenchymal precursor cells
Online Access:https://doi.org/10.1186/s13287-025-04209-5
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