Alpha-globin gene cluster haplotypes and D1S80, D17S5, and TPO VNTR polymorphisms among four ethnic populations from lower northeastern Thailand

Alpha-globin gene cluster haplotypes and D1S80, D17S5, and TPO VNTR polymorphisms among four ethnic populations from lower northeastern Thailand

Abstract Laos, Khmer, Kui, and Yer ethnic populations had a high prevalence of α+-thalassemia, but the genetic background remains poorly understood. This study examined genetic variation at the α-globin gene cluster and three VNTR loci (D1S80, D17S5, and TPO) in these ethnic populations. For α-globi...

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Bibliographic Details
Main Authors: Sanita Singsanan, Wittaya Jomoui, Monpat Chamnanphon, Ruttiya Thongrung, Phairo Saenwang, Anupong Pansuwan, Supan Fucharoen, Rossarin Karnpean
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Scientific Reports
Subjects:
Genetic variation
α-globin gene haplotype
VNTR
Ethnic population
Online Access:https://doi.org/10.1038/s41598-025-91071-3
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