CD8-positive lymphocyte infiltration as a marker of anti-tumor immune response in rectal cancer: pre- and post-neoadjuvant radiotherapy comparison

CD8-positive lymphocyte infiltration as a marker of anti-tumor immune response in rectal cancer: pre- and post-neoadjuvant radiotherapy comparison

Background: Antitumor immunity, exerted by CD8+ cytotoxic T lymphocytes, plays a vital role in tumor control. Therefore, the present study was conducted to compare the amount of CD8+ tumor-infiltrating lymphocytes (TILs) before and after either long- (LCRT) or short-course radiotherapy (SCRT) in rec...

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Bibliographic Details
Main Authors: Samaneh Salarvand, Romina Abyaneh, Abdorreza Raee, Mahdieh Yaghooti-Khorasani, Fariba Mohammadjani, Fatemeh Nili, Mahdi Aghili, Reza Ghalehtaki
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Clinical and Translational Radiation Oncology
Subjects:
Rectal cancer
Neoadjuvant radiotherapy
Tumor-infiltrating CD8-positive lymphocytes
Online Access:http://www.sciencedirect.com/science/article/pii/S2405630825001107
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