Plasma Procalcitonin Is Useful for Predicting the Severity of Acute Cholecystitis
Background. Acute cholecystitis is a common complication of cholelithiasis. Delayed diagnosis may constitute morbidity and mortality; therefore, early diagnosis and determining the severity of acute cholecystitis are crucial. Objectives. This study aimed to determine the validity of blood procalcito...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | Emergency Medicine International |
| Online Access: | http://dx.doi.org/10.1155/2020/8329310 |
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| author | Saben Sakalar Engin Ozakın Arif Alper Cevik Nurdan Acar Serkan Dogan Filiz Baloglu Kaya Taylan Kara |
| author_facet | Saben Sakalar Engin Ozakın Arif Alper Cevik Nurdan Acar Serkan Dogan Filiz Baloglu Kaya Taylan Kara |
| author_sort | Saben Sakalar |
| collection | DOAJ |
| description | Background. Acute cholecystitis is a common complication of cholelithiasis. Delayed diagnosis may constitute morbidity and mortality; therefore, early diagnosis and determining the severity of acute cholecystitis are crucial. Objectives. This study aimed to determine the validity of blood procalcitonin (PCT) levels in assessing the severity of acute cholecystitis. Methods. The Emergency Department (ED) patients diagnosed as acute cholecystitis were included in the study. Patients were allocated into three severity grades according to the Tokyo Guidelines 2013. PCT level was measured after the clinical and radiological diagnosis of acute cholecystitis in the ED. Results. Ninety-five patients diagnosed with acute cholecystitis, among them 48 of were male. Forty patients (42.1%) were allocated to grade 1, 19 (20%) to grade 2, and 36 (37.9%) to grade 3. The median values of PCT were 0.104 ng/ml, 0.353 ng/ml, and 1.466 ng/ml for grade 1, 2, and 3 patients, respectively (p<0.001). Conclusion. Blood procalcitonin levels can be used to determine the severity of acute cholecystitis effectively. |
| format | Article |
| id | doaj-art-ffb581003dda4403b46b675ff727236d |
| institution | Kabale University |
| issn | 2090-2840 2090-2859 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Emergency Medicine International |
| spelling | doaj-art-ffb581003dda4403b46b675ff727236d2025-02-03T06:46:52ZengWileyEmergency Medicine International2090-28402090-28592020-01-01202010.1155/2020/83293108329310Plasma Procalcitonin Is Useful for Predicting the Severity of Acute CholecystitisSaben Sakalar0Engin Ozakın1Arif Alper Cevik2Nurdan Acar3Serkan Dogan4Filiz Baloglu Kaya5Taylan Kara6Eskisehir Osmangazi University Medical Center, Department of Emergency Medicine, Meselik, 26480 Eskisehir, TurkeyEskisehir Osmangazi University Medical Center, Department of Emergency Medicine, Meselik, 26480 Eskisehir, TurkeyDepartments of Internal Medicine, Emergency Medicine Section, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain 17666, UAEEskisehir Osmangazi University Medical Center, Department of Emergency Medicine, Meselik, 26480 Eskisehir, TurkeyEskisehir Osmangazi University Medical Center, Department of Emergency Medicine, Meselik, 26480 Eskisehir, TurkeyEskisehir Osmangazi University Medical Center, Department of Emergency Medicine, Meselik, 26480 Eskisehir, TurkeyEskisehir Osmangazi University Medical Center, Department of Emergency Medicine, Meselik, 26480 Eskisehir, TurkeyBackground. Acute cholecystitis is a common complication of cholelithiasis. Delayed diagnosis may constitute morbidity and mortality; therefore, early diagnosis and determining the severity of acute cholecystitis are crucial. Objectives. This study aimed to determine the validity of blood procalcitonin (PCT) levels in assessing the severity of acute cholecystitis. Methods. The Emergency Department (ED) patients diagnosed as acute cholecystitis were included in the study. Patients were allocated into three severity grades according to the Tokyo Guidelines 2013. PCT level was measured after the clinical and radiological diagnosis of acute cholecystitis in the ED. Results. Ninety-five patients diagnosed with acute cholecystitis, among them 48 of were male. Forty patients (42.1%) were allocated to grade 1, 19 (20%) to grade 2, and 36 (37.9%) to grade 3. The median values of PCT were 0.104 ng/ml, 0.353 ng/ml, and 1.466 ng/ml for grade 1, 2, and 3 patients, respectively (p<0.001). Conclusion. Blood procalcitonin levels can be used to determine the severity of acute cholecystitis effectively.http://dx.doi.org/10.1155/2020/8329310 |
| spellingShingle | Saben Sakalar Engin Ozakın Arif Alper Cevik Nurdan Acar Serkan Dogan Filiz Baloglu Kaya Taylan Kara Plasma Procalcitonin Is Useful for Predicting the Severity of Acute Cholecystitis Emergency Medicine International |
| title | Plasma Procalcitonin Is Useful for Predicting the Severity of Acute Cholecystitis |
| title_full | Plasma Procalcitonin Is Useful for Predicting the Severity of Acute Cholecystitis |
| title_fullStr | Plasma Procalcitonin Is Useful for Predicting the Severity of Acute Cholecystitis |
| title_full_unstemmed | Plasma Procalcitonin Is Useful for Predicting the Severity of Acute Cholecystitis |
| title_short | Plasma Procalcitonin Is Useful for Predicting the Severity of Acute Cholecystitis |
| title_sort | plasma procalcitonin is useful for predicting the severity of acute cholecystitis |
| url | http://dx.doi.org/10.1155/2020/8329310 |
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