Utilizing Cytokines to Function-Enable Human NK Cells for the Immunotherapy of Cancer
Natural killer (NK) cells are innate lymphoid cells important for host defense against pathogens and mediate antitumor immunity. Cytokine receptors transduce important signals that regulate proliferation, survival, activation status, and trigger effector functions. Here, we review the roles of major...
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Main Authors: | Rizwan Romee, Jeffrey W. Leong, Todd A. Fehniger |
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Format: | Article |
Language: | English |
Published: |
Wiley
2014-01-01
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Series: | Scientifica |
Online Access: | http://dx.doi.org/10.1155/2014/205796 |
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