Potential of photodynamic therapy using polycationic photosensitizers in the treatment of lung cancer patients with SARS-CoV-2 infection and bacterial complications: Our recent experience
The problem of treating cancer patients with lung cancer has become more difficult due to the SARS-CoV-2 viral infection and concomitant bacterial lesions. The analysis shows that the photodynamic effect of long-wavelength polycationic photosensitizers suppresses the tumor process (including the des...
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| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2025-02-01
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| Series: | Photodiagnosis and Photodynamic Therapy |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1572100024004836 |
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| author | Gennady Meerovich Evgeniya Kogan Igor Romanishkin Nikolay Zharkov Sofiya Avraamova Elena Shchelokova Ekaterina Akhlyustina Marina Strakhovskaya Irina Meerovich Sofya Demura Irina Tiganova Yulia Romanova Zhi-Long Chen Igor Reshetov |
| author_facet | Gennady Meerovich Evgeniya Kogan Igor Romanishkin Nikolay Zharkov Sofiya Avraamova Elena Shchelokova Ekaterina Akhlyustina Marina Strakhovskaya Irina Meerovich Sofya Demura Irina Tiganova Yulia Romanova Zhi-Long Chen Igor Reshetov |
| author_sort | Gennady Meerovich |
| collection | DOAJ |
| description | The problem of treating cancer patients with lung cancer has become more difficult due to the SARS-CoV-2 viral infection and concomitant bacterial lesions. The analysis shows that the photodynamic effect of long-wavelength polycationic photosensitizers suppresses the tumor process (including the destruction of cancer stem cells), SARS-CoV-2 coronavirus infection, Gram-positive and Gram-negative bacteria, including those that can cause pneumonia. Therefore, the photodynamic approach using such photosensitizers is promising for the development of an effective treatment method for patients with lung cancer, including those with SARS-CoV-2 infection and bacterial complications. |
| format | Article |
| id | doaj-art-ff93af1f9dc943f0b7bd530ede3f053a |
| institution | Kabale University |
| issn | 1572-1000 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Photodiagnosis and Photodynamic Therapy |
| spelling | doaj-art-ff93af1f9dc943f0b7bd530ede3f053a2025-02-01T04:11:44ZengElsevierPhotodiagnosis and Photodynamic Therapy1572-10002025-02-0151104447Potential of photodynamic therapy using polycationic photosensitizers in the treatment of lung cancer patients with SARS-CoV-2 infection and bacterial complications: Our recent experienceGennady Meerovich0Evgeniya Kogan1Igor Romanishkin2Nikolay Zharkov3Sofiya Avraamova4Elena Shchelokova5Ekaterina Akhlyustina6Marina Strakhovskaya7Irina Meerovich8Sofya Demura9Irina Tiganova10Yulia Romanova11Zhi-Long Chen12Igor Reshetov13Prokhorov General Physics Institute of the Russian Academy of Sciences, Moscow 119991, Russia; Institute for Physics and Engineering in Biomedicine, National Research Nuclear University MEPhI (Moscow Engineering Physics Institute), Moscow 115409, RussiaI.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow 119992, RussiaProkhorov General Physics Institute of the Russian Academy of Sciences, Moscow 119991, Russia; Corresponding author.I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow 119992, RussiaI.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow 119992, RussiaI.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow 119992, RussiaInstitute for Physics and Engineering in Biomedicine, National Research Nuclear University MEPhI (Moscow Engineering Physics Institute), Moscow 115409, RussiaLomonosov Moscow State University, Moscow 119991, RussiaResearch Center of Biotechnology of the Russian Academy of Sciences, A.N. Bach Institute of Biochemistry, Moscow 119071, RussiaInstitute for Physics and Engineering in Biomedicine, National Research Nuclear University MEPhI (Moscow Engineering Physics Institute), Moscow 115409, RussiaLomonosov Moscow State University, Moscow 119991, RussiaLomonosov Moscow State University, Moscow 119991, RussiaHuadong Hospital, Fudan University, Shanghai 200040, ChinaInstitute for Physics and Engineering in Biomedicine, National Research Nuclear University MEPhI (Moscow Engineering Physics Institute), Moscow 115409, RussiaThe problem of treating cancer patients with lung cancer has become more difficult due to the SARS-CoV-2 viral infection and concomitant bacterial lesions. The analysis shows that the photodynamic effect of long-wavelength polycationic photosensitizers suppresses the tumor process (including the destruction of cancer stem cells), SARS-CoV-2 coronavirus infection, Gram-positive and Gram-negative bacteria, including those that can cause pneumonia. Therefore, the photodynamic approach using such photosensitizers is promising for the development of an effective treatment method for patients with lung cancer, including those with SARS-CoV-2 infection and bacterial complications.http://www.sciencedirect.com/science/article/pii/S1572100024004836SARS-CoV-2Lung cancerBacteriaPhotodynamic therapy |
| spellingShingle | Gennady Meerovich Evgeniya Kogan Igor Romanishkin Nikolay Zharkov Sofiya Avraamova Elena Shchelokova Ekaterina Akhlyustina Marina Strakhovskaya Irina Meerovich Sofya Demura Irina Tiganova Yulia Romanova Zhi-Long Chen Igor Reshetov Potential of photodynamic therapy using polycationic photosensitizers in the treatment of lung cancer patients with SARS-CoV-2 infection and bacterial complications: Our recent experience Photodiagnosis and Photodynamic Therapy SARS-CoV-2 Lung cancer Bacteria Photodynamic therapy |
| title | Potential of photodynamic therapy using polycationic photosensitizers in the treatment of lung cancer patients with SARS-CoV-2 infection and bacterial complications: Our recent experience |
| title_full | Potential of photodynamic therapy using polycationic photosensitizers in the treatment of lung cancer patients with SARS-CoV-2 infection and bacterial complications: Our recent experience |
| title_fullStr | Potential of photodynamic therapy using polycationic photosensitizers in the treatment of lung cancer patients with SARS-CoV-2 infection and bacterial complications: Our recent experience |
| title_full_unstemmed | Potential of photodynamic therapy using polycationic photosensitizers in the treatment of lung cancer patients with SARS-CoV-2 infection and bacterial complications: Our recent experience |
| title_short | Potential of photodynamic therapy using polycationic photosensitizers in the treatment of lung cancer patients with SARS-CoV-2 infection and bacterial complications: Our recent experience |
| title_sort | potential of photodynamic therapy using polycationic photosensitizers in the treatment of lung cancer patients with sars cov 2 infection and bacterial complications our recent experience |
| topic | SARS-CoV-2 Lung cancer Bacteria Photodynamic therapy |
| url | http://www.sciencedirect.com/science/article/pii/S1572100024004836 |
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