Increased prevalence of obstructive sleep apnea in patients with pectus excavatum: A pilot study

Objective: Laryngomalacia is the most common congenital laryngeal anomaly and is associated with pectus excavatum (PE). Patients with laryngomalacia and patients with obstructive sleep apnea (OSA) both experience upper airway obstruction, and patients with laryngomalacia had been found to have a hig...

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Main Authors: Yeung-Leung Cheng, I-Shiang Tzeng, Mei-Chen Yang
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2018-01-01
Series:Tzu Chi Medical Journal
Subjects:
Online Access:http://www.tcmjmed.com/article.asp?issn=1016-3190;year=2018;volume=30;issue=4;spage=233;epage=237;aulast=Cheng
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author Yeung-Leung Cheng
I-Shiang Tzeng
Mei-Chen Yang
author_facet Yeung-Leung Cheng
I-Shiang Tzeng
Mei-Chen Yang
author_sort Yeung-Leung Cheng
collection DOAJ
description Objective: Laryngomalacia is the most common congenital laryngeal anomaly and is associated with pectus excavatum (PE). Patients with laryngomalacia and patients with obstructive sleep apnea (OSA) both experience upper airway obstruction, and patients with laryngomalacia had been found to have a higher prevalence of PE. However, no studies have established the prevalence of OSA in patients with PE. We conducted this pilot study to evaluate the prevalence of OSA in patients with PE. Materials and Methods: A total of 42 patients ≥20 years old with PE who were admitted for Nuss surgery to correct PE in Taipei Tzu Chi Hospital between October 2015 and September 2016 were invited to participate in the study; 31 of the 42 patients agreed. All 31 patients completed an Epworth sleepiness scale questionnaire to evaluate excessive daytime sleepiness (EDS) and underwent overnight polysomnography to evaluate OSA before Nuss surgery. Results: The prevalence of snoring in the study participants was 100%. Ten of 31 patients (32.3%) reported EDS. The overall prevalence of OSA with an apnea/hypopnea index ≥5/h was 25.8%, and all patients with OSA were men. Conclusions: The prevalence of OSA in patients with PE seemed to be higher than that previously reported in the general population, implying that OSA might be a potential etiology or, at least, an aggravating factor for the development or progression of PE or might be responsible for the postoperative recurrence of PE in some patients. Further studies are needed to clarify this relationship.
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spelling doaj-art-ff8de35b27a7422dbda2d66d23d4b7232025-08-20T02:04:48ZengWolters Kluwer Medknow PublicationsTzu Chi Medical Journal1016-31902223-89562018-01-0130423323710.4103/tcmj.tcmj_115_17Increased prevalence of obstructive sleep apnea in patients with pectus excavatum: A pilot studyYeung-Leung ChengI-Shiang TzengMei-Chen YangObjective: Laryngomalacia is the most common congenital laryngeal anomaly and is associated with pectus excavatum (PE). Patients with laryngomalacia and patients with obstructive sleep apnea (OSA) both experience upper airway obstruction, and patients with laryngomalacia had been found to have a higher prevalence of PE. However, no studies have established the prevalence of OSA in patients with PE. We conducted this pilot study to evaluate the prevalence of OSA in patients with PE. Materials and Methods: A total of 42 patients ≥20 years old with PE who were admitted for Nuss surgery to correct PE in Taipei Tzu Chi Hospital between October 2015 and September 2016 were invited to participate in the study; 31 of the 42 patients agreed. All 31 patients completed an Epworth sleepiness scale questionnaire to evaluate excessive daytime sleepiness (EDS) and underwent overnight polysomnography to evaluate OSA before Nuss surgery. Results: The prevalence of snoring in the study participants was 100%. Ten of 31 patients (32.3%) reported EDS. The overall prevalence of OSA with an apnea/hypopnea index ≥5/h was 25.8%, and all patients with OSA were men. Conclusions: The prevalence of OSA in patients with PE seemed to be higher than that previously reported in the general population, implying that OSA might be a potential etiology or, at least, an aggravating factor for the development or progression of PE or might be responsible for the postoperative recurrence of PE in some patients. Further studies are needed to clarify this relationship.http://www.tcmjmed.com/article.asp?issn=1016-3190;year=2018;volume=30;issue=4;spage=233;epage=237;aulast=ChengObstructive sleep apneaPectus excavatumPrevalence
spellingShingle Yeung-Leung Cheng
I-Shiang Tzeng
Mei-Chen Yang
Increased prevalence of obstructive sleep apnea in patients with pectus excavatum: A pilot study
Tzu Chi Medical Journal
Obstructive sleep apnea
Pectus excavatum
Prevalence
title Increased prevalence of obstructive sleep apnea in patients with pectus excavatum: A pilot study
title_full Increased prevalence of obstructive sleep apnea in patients with pectus excavatum: A pilot study
title_fullStr Increased prevalence of obstructive sleep apnea in patients with pectus excavatum: A pilot study
title_full_unstemmed Increased prevalence of obstructive sleep apnea in patients with pectus excavatum: A pilot study
title_short Increased prevalence of obstructive sleep apnea in patients with pectus excavatum: A pilot study
title_sort increased prevalence of obstructive sleep apnea in patients with pectus excavatum a pilot study
topic Obstructive sleep apnea
Pectus excavatum
Prevalence
url http://www.tcmjmed.com/article.asp?issn=1016-3190;year=2018;volume=30;issue=4;spage=233;epage=237;aulast=Cheng
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AT ishiangtzeng increasedprevalenceofobstructivesleepapneainpatientswithpectusexcavatumapilotstudy
AT meichenyang increasedprevalenceofobstructivesleepapneainpatientswithpectusexcavatumapilotstudy