A change in circulating chikungunya virus variant impacts Aedes aegypti vector competence and spatiotemporal distribution of disease in Malaysia.

A change in circulating chikungunya virus variant impacts Aedes aegypti vector competence and spatiotemporal distribution of disease in Malaysia.

<h4>Background</h4>In 2008-2010, Malaysia experienced a nationwide chikungunya virus (CHIKV) outbreak caused by the Indian Ocean lineage E1-226V (valine) variant, adapted to Aedes albopictus. In 2017-2022, transition to an E1-226A (alanine) variant occurred. Ae. albopictus prevails in ru...

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Main Authors: Izzati Kausar Azman, Yoke Fun Chan, Chong Long Chua, Zainal Abidin Abd Mutalib, Sarat Chandra Dass, Balvinder Singh Gill, Nor Hayati Ismail, Jenarun Jelip, Ming Keong Wan, Wenn-Chyau Lee, Indra Vythilingam, Luke Alphey, I-Ching Sam
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-10-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0012632
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