Concomitant Extramedullary Plasmacytoma in the Oropharynx and Hypopharyngeal Squamous Cell Carcinoma

We report a rare case of hypopharyngeal squamous cell carcinoma occurring synchronously with extramedullary plasmacytoma (EPM) of the oropharynx in which radiotherapy was used as the curative treatment. A 73-year-old man presented with a sore throat that had persisted for 6 months. Examination revea...

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Main Authors: Hiroki Sato, Shoko Yoshimasu, Isaku Okamoto, Akira Shimizu, Yasuaki Katsube, Hideki Tanaka, Kiyoaki Tsukahara
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Case Reports in Otolaryngology
Online Access:http://dx.doi.org/10.1155/2018/1463218
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author Hiroki Sato
Shoko Yoshimasu
Isaku Okamoto
Akira Shimizu
Yasuaki Katsube
Hideki Tanaka
Kiyoaki Tsukahara
author_facet Hiroki Sato
Shoko Yoshimasu
Isaku Okamoto
Akira Shimizu
Yasuaki Katsube
Hideki Tanaka
Kiyoaki Tsukahara
author_sort Hiroki Sato
collection DOAJ
description We report a rare case of hypopharyngeal squamous cell carcinoma occurring synchronously with extramedullary plasmacytoma (EPM) of the oropharynx in which radiotherapy was used as the curative treatment. A 73-year-old man presented with a sore throat that had persisted for 6 months. Examination revealed a superficial, smooth tumorous lesion at the base of his tongue with a red hue in the oropharynx. In addition, a protruding tumor was observed on the mucosal surface in the right piriform recess of the hypopharynx, and computed tomography revealed thickening of the pharyngeal wall at the right tongue base and in the right piriform recess of the hypopharynx. Because no definitive diagnosis could be reached for the lesion at the base of the tongue, the entire tongue-base tumor was resected by transoral surgery under endoscopy. Proliferation of plasma cells in the tumor was detected, and a bone marrow puncture test ruled out multiple myeloma leading to a definitive diagnosis of Stage I (cT1N0M0) squamous cell carcinoma in the right piriform recess of the hypopharynx and primary extramedullary plasmacytoma in the oropharynx. Radiotherapy was selected for curative treatment with a complete response for both cancers. No recurrences have been observed as of 12 months postoperatively.
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spelling doaj-art-ff632638570a47faac23a7705d3995212025-02-03T01:25:38ZengWileyCase Reports in Otolaryngology2090-67652090-67732018-01-01201810.1155/2018/14632181463218Concomitant Extramedullary Plasmacytoma in the Oropharynx and Hypopharyngeal Squamous Cell CarcinomaHiroki Sato0Shoko Yoshimasu1Isaku Okamoto2Akira Shimizu3Yasuaki Katsube4Hideki Tanaka5Kiyoaki Tsukahara6Department of Otorhinolaryngology, Head and Neck Surgery, Tokyo Medical University, Tokyo, JapanDepartment of Otorhinolaryngology, Head and Neck Surgery, Tokyo Medical University, Tokyo, JapanDepartment of Otorhinolaryngology, Head and Neck Surgery, Tokyo Medical University, Tokyo, JapanDepartment of Otorhinolaryngology, Head and Neck Surgery, Tokyo Medical University, Tokyo, JapanDepartment of Otorhinolaryngology, Head and Neck Surgery, Tokyo Medical University, Tokyo, JapanDepartment of Otorhinolaryngology, Head and Neck Surgery, Tokyo Medical University, Tokyo, JapanDepartment of Otorhinolaryngology, Head and Neck Surgery, Tokyo Medical University, Tokyo, JapanWe report a rare case of hypopharyngeal squamous cell carcinoma occurring synchronously with extramedullary plasmacytoma (EPM) of the oropharynx in which radiotherapy was used as the curative treatment. A 73-year-old man presented with a sore throat that had persisted for 6 months. Examination revealed a superficial, smooth tumorous lesion at the base of his tongue with a red hue in the oropharynx. In addition, a protruding tumor was observed on the mucosal surface in the right piriform recess of the hypopharynx, and computed tomography revealed thickening of the pharyngeal wall at the right tongue base and in the right piriform recess of the hypopharynx. Because no definitive diagnosis could be reached for the lesion at the base of the tongue, the entire tongue-base tumor was resected by transoral surgery under endoscopy. Proliferation of plasma cells in the tumor was detected, and a bone marrow puncture test ruled out multiple myeloma leading to a definitive diagnosis of Stage I (cT1N0M0) squamous cell carcinoma in the right piriform recess of the hypopharynx and primary extramedullary plasmacytoma in the oropharynx. Radiotherapy was selected for curative treatment with a complete response for both cancers. No recurrences have been observed as of 12 months postoperatively.http://dx.doi.org/10.1155/2018/1463218
spellingShingle Hiroki Sato
Shoko Yoshimasu
Isaku Okamoto
Akira Shimizu
Yasuaki Katsube
Hideki Tanaka
Kiyoaki Tsukahara
Concomitant Extramedullary Plasmacytoma in the Oropharynx and Hypopharyngeal Squamous Cell Carcinoma
Case Reports in Otolaryngology
title Concomitant Extramedullary Plasmacytoma in the Oropharynx and Hypopharyngeal Squamous Cell Carcinoma
title_full Concomitant Extramedullary Plasmacytoma in the Oropharynx and Hypopharyngeal Squamous Cell Carcinoma
title_fullStr Concomitant Extramedullary Plasmacytoma in the Oropharynx and Hypopharyngeal Squamous Cell Carcinoma
title_full_unstemmed Concomitant Extramedullary Plasmacytoma in the Oropharynx and Hypopharyngeal Squamous Cell Carcinoma
title_short Concomitant Extramedullary Plasmacytoma in the Oropharynx and Hypopharyngeal Squamous Cell Carcinoma
title_sort concomitant extramedullary plasmacytoma in the oropharynx and hypopharyngeal squamous cell carcinoma
url http://dx.doi.org/10.1155/2018/1463218
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