JN.1 variants circulating in Italy from October 2023 to April 2024: genetic diversity and immune recognition

JN.1 variants circulating in Italy from October 2023 to April 2024: genetic diversity and immune recognition

Abstract Background The continuous emergence of SARS-CoV-2 variants and subvariants poses significant public health challenges. The latest designated subvariant JN.1, with all its descendants, shows more than 30 mutations in the spike gene. JN.1 has raised concerns due to its genomic diversity and i...

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Main Authors: Emanuela Giombini, Ilaria Schiavoni, Luigina Ambrosio, Alessandra Lo Presti, Angela Di Martino, Stefano Fiore, Pasqualina Leone, Francesca Fortunato, Rosa Prato, Giorgio Fedele, Anna Teresa Palamara, Paola Stefanelli, the Italian Genomic Laboratory Network
Format: Article
Language:English
Published: BMC 2025-02-01
Series:BMC Infectious Diseases
Subjects:
SARS-CoV-2
JN.1
Genomic surveillance
Phylogenetic analysis
Neutralizing antibodies
Online Access:https://doi.org/10.1186/s12879-025-10685-0
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