Short Interval Infield Sarcoma Development following Resection of Glioblastoma and Adjuvant Radiotherapy and Temozolomide

Background. The development of 2 unassociated brain cancers in the same patient is a rare occurrence. Secondary cancers are generally thought to develop as an oncogenic consequence of the radiation therapy delivered to treat the primary cancers, always requiring a significant time interval between r...

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Main Authors: Fahad E. Alotaibi, Kevin Petrecca
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2013/591272
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author Fahad E. Alotaibi
Kevin Petrecca
author_facet Fahad E. Alotaibi
Kevin Petrecca
author_sort Fahad E. Alotaibi
collection DOAJ
description Background. The development of 2 unassociated brain cancers in the same patient is a rare occurrence. Secondary cancers are generally thought to develop as an oncogenic consequence of the radiation therapy delivered to treat the primary cancers, always requiring a significant time interval between radiation treatment and secondary cancer development. Case Description. We report the development of an undifferentiated myxoid sarcoma only 13 months following radiation therapy for a glioblastoma. Conclusion. This case represents the shortest time interval reported between radiation therapy and secondary brain cancer development.
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spelling doaj-art-ff4bdbbb8a6e4e829adbef169ad9a7362025-08-20T02:22:45ZengWileyCase Reports in Medicine1687-96271687-96352013-01-01201310.1155/2013/591272591272Short Interval Infield Sarcoma Development following Resection of Glioblastoma and Adjuvant Radiotherapy and TemozolomideFahad E. Alotaibi0Kevin Petrecca1Department of Neurology and Neurosurgery, Montreal Neurological Institute and Hospital, McGill University and Department of Neurosurgery, McGill University Health Centre, 3801 University Avenue, 109 Montreal, QC, H3A 2B4, CanadaDepartment of Neurology and Neurosurgery, Montreal Neurological Institute and Hospital, McGill University and Department of Neurosurgery, McGill University Health Centre, 3801 University Avenue, 109 Montreal, QC, H3A 2B4, CanadaBackground. The development of 2 unassociated brain cancers in the same patient is a rare occurrence. Secondary cancers are generally thought to develop as an oncogenic consequence of the radiation therapy delivered to treat the primary cancers, always requiring a significant time interval between radiation treatment and secondary cancer development. Case Description. We report the development of an undifferentiated myxoid sarcoma only 13 months following radiation therapy for a glioblastoma. Conclusion. This case represents the shortest time interval reported between radiation therapy and secondary brain cancer development.http://dx.doi.org/10.1155/2013/591272
spellingShingle Fahad E. Alotaibi
Kevin Petrecca
Short Interval Infield Sarcoma Development following Resection of Glioblastoma and Adjuvant Radiotherapy and Temozolomide
Case Reports in Medicine
title Short Interval Infield Sarcoma Development following Resection of Glioblastoma and Adjuvant Radiotherapy and Temozolomide
title_full Short Interval Infield Sarcoma Development following Resection of Glioblastoma and Adjuvant Radiotherapy and Temozolomide
title_fullStr Short Interval Infield Sarcoma Development following Resection of Glioblastoma and Adjuvant Radiotherapy and Temozolomide
title_full_unstemmed Short Interval Infield Sarcoma Development following Resection of Glioblastoma and Adjuvant Radiotherapy and Temozolomide
title_short Short Interval Infield Sarcoma Development following Resection of Glioblastoma and Adjuvant Radiotherapy and Temozolomide
title_sort short interval infield sarcoma development following resection of glioblastoma and adjuvant radiotherapy and temozolomide
url http://dx.doi.org/10.1155/2013/591272
work_keys_str_mv AT fahadealotaibi shortintervalinfieldsarcomadevelopmentfollowingresectionofglioblastomaandadjuvantradiotherapyandtemozolomide
AT kevinpetrecca shortintervalinfieldsarcomadevelopmentfollowingresectionofglioblastomaandadjuvantradiotherapyandtemozolomide