Frequency and Clinical Features of Dengue Infection in a Schoolchildren Cohort from Medellin, Colombia
To determine the incidence of dengue infection, we established active surveillance of febrile episodes in a cohort of schoolchildren from three schools in Medellin, Colombia. We followed a cohort of 2,379 schoolchildren in 2010 and followed 1,840 of these children the following year. During the foll...
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2012-01-01
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| Series: | Journal of Tropical Medicine |
| Online Access: | http://dx.doi.org/10.1155/2012/120496 |
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| author | Berta Nelly Restrepo Leidy Diana Piedrahita Ivony Yireth Agudelo Gabriel Parra-Henao Jorge E. Osorio |
| author_facet | Berta Nelly Restrepo Leidy Diana Piedrahita Ivony Yireth Agudelo Gabriel Parra-Henao Jorge E. Osorio |
| author_sort | Berta Nelly Restrepo |
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| description | To determine the incidence of dengue infection, we established active surveillance of febrile episodes in a cohort of schoolchildren from three schools in Medellin, Colombia. We followed a cohort of 2,379 schoolchildren in 2010 and followed 1,840 of these children the following year. During the follow-up time, 264 schoolchildren displayed 297 febrile episodes; of these, 23 episodes (7.7%) were caused by acute dengue infection. All four dengue serotypes were found, and all of the cases were mild. The most common symptoms in the dengue cases compared with those in other febrile illness were asthenia (96% versus 87%), anorexia (78% versus 57%), rhinorrhea (65.2% versus 58%), abdominal pain (56.5% versus 47.8%), arthralgia (43% versus 33%), and positive tourniquet test (13% versus 3%). This difference was not statistically significant. Pulse was elevated, and systolic arterial pressure was lower in dengue cases compared with other febrile illness (P<0.05). Mosquito indexes were determined in 8 children’s houses and in the schools. Aedes aegypti adults were found in both households and in schools, whereas Aedes aegypti larvae were found only in schools. These results showed an elevated dengue frequency in children, with symptoms similar to those of other febrile illness and transmission risk in households and schools. |
| format | Article |
| id | doaj-art-ff1d28fb52834d4491ff40e89a188eec |
| institution | Kabale University |
| issn | 1687-9686 1687-9694 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
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| series | Journal of Tropical Medicine |
| spelling | doaj-art-ff1d28fb52834d4491ff40e89a188eec2025-02-03T06:42:27ZengWileyJournal of Tropical Medicine1687-96861687-96942012-01-01201210.1155/2012/120496120496Frequency and Clinical Features of Dengue Infection in a Schoolchildren Cohort from Medellin, ColombiaBerta Nelly Restrepo0Leidy Diana Piedrahita1Ivony Yireth Agudelo2Gabriel Parra-Henao3Jorge E. Osorio4Instituto Colombiano de Medicina Tropical, Universidad CES, Carrera 43, No. 52S99, Sabaneta, ColombiaInstituto Colombiano de Medicina Tropical, Universidad CES, Carrera 43, No. 52S99, Sabaneta, ColombiaInstituto Colombiano de Medicina Tropical, Universidad CES, Carrera 43, No. 52S99, Sabaneta, ColombiaInstituto Colombiano de Medicina Tropical, Universidad CES, Carrera 43, No. 52S99, Sabaneta, ColombiaDepartment of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, 1656 Linden Drive, Madison, WI 53706, USATo determine the incidence of dengue infection, we established active surveillance of febrile episodes in a cohort of schoolchildren from three schools in Medellin, Colombia. We followed a cohort of 2,379 schoolchildren in 2010 and followed 1,840 of these children the following year. During the follow-up time, 264 schoolchildren displayed 297 febrile episodes; of these, 23 episodes (7.7%) were caused by acute dengue infection. All four dengue serotypes were found, and all of the cases were mild. The most common symptoms in the dengue cases compared with those in other febrile illness were asthenia (96% versus 87%), anorexia (78% versus 57%), rhinorrhea (65.2% versus 58%), abdominal pain (56.5% versus 47.8%), arthralgia (43% versus 33%), and positive tourniquet test (13% versus 3%). This difference was not statistically significant. Pulse was elevated, and systolic arterial pressure was lower in dengue cases compared with other febrile illness (P<0.05). Mosquito indexes were determined in 8 children’s houses and in the schools. Aedes aegypti adults were found in both households and in schools, whereas Aedes aegypti larvae were found only in schools. These results showed an elevated dengue frequency in children, with symptoms similar to those of other febrile illness and transmission risk in households and schools.http://dx.doi.org/10.1155/2012/120496 |
| spellingShingle | Berta Nelly Restrepo Leidy Diana Piedrahita Ivony Yireth Agudelo Gabriel Parra-Henao Jorge E. Osorio Frequency and Clinical Features of Dengue Infection in a Schoolchildren Cohort from Medellin, Colombia Journal of Tropical Medicine |
| title | Frequency and Clinical Features of Dengue Infection in a Schoolchildren Cohort from Medellin, Colombia |
| title_full | Frequency and Clinical Features of Dengue Infection in a Schoolchildren Cohort from Medellin, Colombia |
| title_fullStr | Frequency and Clinical Features of Dengue Infection in a Schoolchildren Cohort from Medellin, Colombia |
| title_full_unstemmed | Frequency and Clinical Features of Dengue Infection in a Schoolchildren Cohort from Medellin, Colombia |
| title_short | Frequency and Clinical Features of Dengue Infection in a Schoolchildren Cohort from Medellin, Colombia |
| title_sort | frequency and clinical features of dengue infection in a schoolchildren cohort from medellin colombia |
| url | http://dx.doi.org/10.1155/2012/120496 |
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