FEN1 plays a key role in the transition from HSIL to CSCC

FEN1 plays a key role in the transition from HSIL to CSCC

Abstract Cervical high-grade squamous intraepithelial lesion (HSIL) is a well-recognized precursor to cervical squamous cell carcinoma (CSCC). This study aims to explore molecular mechanisms underlying this transition. The datasets of HSIL and CSCC were downloaded from gene expression omnibus databa...

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Bibliographic Details
Main Authors: Fengxian Zhang, Xiaomei Chen, Chenyang Chu, Meilin Chen, Ying Yang, Yanting You, Jie Zhou, Pingping Jiang, Ni Song, Yunhong Yu, Yanyan Liu
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
Subjects:
High-grade squamous intraepithelial lesion
Cervical squamous cell carcinoma
Immune infiltration
Potential biomarker
Flap endonuclease 1
Online Access:https://doi.org/10.1038/s41598-025-15642-0
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