Comprehensive evaluation of clinical phenotypes and pathogenic features in late-onset monogenic inflammatory bowel disease: a comparative study with infantile-onset cases

Comprehensive evaluation of clinical phenotypes and pathogenic features in late-onset monogenic inflammatory bowel disease: a comparative study with infantile-onset cases

Abstract Background Monogenic inflammatory bowel disease (mIBD) in patients with onset after the age of 16 has been increasingly recognized, but these reports are sporadic and lack a systematic overview, leaving the clinical and genetic characteristics poorly understood. This study aimed to characte...

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Bibliographic Details
Main Authors: Haoying Liu, Yinxian Shen, Jiaxin Xu, Shangzhan Huang, TingTing Qin, Qi Zhou, Jiazhi Liao, Fang Xiao
Format: Article
Language:English
Published: BMC 2025-06-01
Series:BMC Gastroenterology
Subjects:
IBD
Monogenic disorders
Late-onset
Phenotypes
Online Access:https://doi.org/10.1186/s12876-025-04041-4
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