In Vitro and In Silico Anthelmintic Activity of Extracts of Lannea kerstingii and Ficus thonningii on Heligmosomoides polygyrus

Conclusion: The use of L. kerstingii and F. thonningii for the treatment of helminthiasis has been proved in vitro and in silico by this research. However, more research is required, especially on the acute toxicity and in vivo anthelmintic efficacy to validate this scientific investigation.

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Main Authors: Ndjinkeu Ntcheuzing Serena, Masoud Besati, Noumedem Anangmo Christelle Nadia, Mahdi Yaghoobi, Yamssi Cédric, Claire Ciancia, Ngouyamsa Nsapkain Aboubakar Sidiki, Vincent Khan Payne, Mpoame Mbida, Haibo Hu
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Journal of Parasitology Research
Online Access:http://dx.doi.org/10.1155/2024/1858154
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author Ndjinkeu Ntcheuzing Serena
Masoud Besati
Noumedem Anangmo Christelle Nadia
Mahdi Yaghoobi
Yamssi Cédric
Claire Ciancia
Ngouyamsa Nsapkain Aboubakar Sidiki
Vincent Khan Payne
Mpoame Mbida
Haibo Hu
author_facet Ndjinkeu Ntcheuzing Serena
Masoud Besati
Noumedem Anangmo Christelle Nadia
Mahdi Yaghoobi
Yamssi Cédric
Claire Ciancia
Ngouyamsa Nsapkain Aboubakar Sidiki
Vincent Khan Payne
Mpoame Mbida
Haibo Hu
author_sort Ndjinkeu Ntcheuzing Serena
collection DOAJ
description Conclusion: The use of L. kerstingii and F. thonningii for the treatment of helminthiasis has been proved in vitro and in silico by this research. However, more research is required, especially on the acute toxicity and in vivo anthelmintic efficacy to validate this scientific investigation.
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institution Kabale University
issn 2090-0031
language English
publishDate 2024-01-01
publisher Wiley
record_format Article
series Journal of Parasitology Research
spelling doaj-art-fea78772f2d049c4a29e1b85b2e5906b2025-02-03T09:39:33ZengWileyJournal of Parasitology Research2090-00312024-01-01202410.1155/2024/1858154In Vitro and In Silico Anthelmintic Activity of Extracts of Lannea kerstingii and Ficus thonningii on Heligmosomoides polygyrusNdjinkeu Ntcheuzing Serena0Masoud Besati1Noumedem Anangmo Christelle Nadia2Mahdi Yaghoobi3Yamssi Cédric4Claire Ciancia5Ngouyamsa Nsapkain Aboubakar Sidiki6Vincent Khan Payne7Mpoame Mbida8Haibo Hu9Department of Animal BiologyInstitute for Integrative Systems Biology (I2SysBio)Laboratory of Tropical and Emerging Infectious DiseasesMolecular Design and SynthesisLaboratory of Tropical and Emerging Infectious DiseasesWellcome Centre for Molecular ParasitologyDepartment of Animal BiologyDepartment of Animal BiologyDepartment of Animal BiologyLaboratory of Tropical and Emerging Infectious DiseasesConclusion: The use of L. kerstingii and F. thonningii for the treatment of helminthiasis has been proved in vitro and in silico by this research. However, more research is required, especially on the acute toxicity and in vivo anthelmintic efficacy to validate this scientific investigation.http://dx.doi.org/10.1155/2024/1858154
spellingShingle Ndjinkeu Ntcheuzing Serena
Masoud Besati
Noumedem Anangmo Christelle Nadia
Mahdi Yaghoobi
Yamssi Cédric
Claire Ciancia
Ngouyamsa Nsapkain Aboubakar Sidiki
Vincent Khan Payne
Mpoame Mbida
Haibo Hu
In Vitro and In Silico Anthelmintic Activity of Extracts of Lannea kerstingii and Ficus thonningii on Heligmosomoides polygyrus
Journal of Parasitology Research
title In Vitro and In Silico Anthelmintic Activity of Extracts of Lannea kerstingii and Ficus thonningii on Heligmosomoides polygyrus
title_full In Vitro and In Silico Anthelmintic Activity of Extracts of Lannea kerstingii and Ficus thonningii on Heligmosomoides polygyrus
title_fullStr In Vitro and In Silico Anthelmintic Activity of Extracts of Lannea kerstingii and Ficus thonningii on Heligmosomoides polygyrus
title_full_unstemmed In Vitro and In Silico Anthelmintic Activity of Extracts of Lannea kerstingii and Ficus thonningii on Heligmosomoides polygyrus
title_short In Vitro and In Silico Anthelmintic Activity of Extracts of Lannea kerstingii and Ficus thonningii on Heligmosomoides polygyrus
title_sort in vitro and in silico anthelmintic activity of extracts of lannea kerstingii and ficus thonningii on heligmosomoides polygyrus
url http://dx.doi.org/10.1155/2024/1858154
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