The zinc receptor, ZnR/GPR39, modulates taste sensitivity by regulating ion secretion in mouse salivary gland

The zinc receptor, ZnR/GPR39, modulates taste sensitivity by regulating ion secretion in mouse salivary gland

Summary: Reduced saliva secretion, dry mouth, and loss of taste are debilitating symptoms associated with zinc deficiency. A mechanism for zinc regulation of these processes is lacking. Here, we identified the Zn2+ sensing receptor ZnR/GPR39 as a mediator of ion transport in salivary gland epitheliu...

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Bibliographic Details
Main Authors: Moran Melamed, Hila Asraf, Noa Livne, Milos Bogdanovic, Anil Shendge, Gilad Shamir, Maayan Mero, Omer Adir, Avi Schroeder, Israel Sekler, Michal Hershfinkel
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:iScience
Subjects:
Natural sciences
Biological sciences
Biochemistry
Physiology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004225001725
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