The RFTS domain of Raf2 is required for Cul4 interaction and heterochromatin integrity in fission yeast.

The RFTS domain of Raf2 is required for Cul4 interaction and heterochromatin integrity in fission yeast.

Centromeric heterochromatin assembly in fission yeast is critical for faithful chromosome segregation at mitosis. Its assembly requires a concerted pathway of events whereby the RNA interference (RNAi) pathway guides H3K9 methylation to target sequences. H3K9 methylation, a hallmark of heterochromat...

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Bibliographic Details
Main Authors: Sharon A White, Alessia Buscaino, Luis Sanchez-Pulido, Chris P Ponting, Matthew W Nowicki, Robin C Allshire
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0104161
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